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25-04-2024 | Type 1 Diabetes | Invited Review

Vitamin D efficacy in type 1 and type 2 diabetes

Authors: Tetsuya Kawahara, Yosuke Okada, Yoshiya Tanaka

Published in: Journal of Bone and Mineral Metabolism

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Abstract

It is well known that vitamin D has a profound effect on calcium and bone metabolism, but its influence on other organs (extraskeletal effect) has been proposed. Consistently, vitamin D deficiency is associated with an increased incidence of various diseases, including type 1 and type 2 diabetes, as reported by many observational studies. However, there has been no consensus on whether vitamin D deficiency is a causative factor in the incidence of diabetes mellitus. There have been no randomized controlled trials (RCTs) aimed at preventing the onset of type 1 diabetes with vitamin D intake. In addition, the results of RCTs evaluating the preventive effect of vitamin D supplementation on type 2 diabetes development have been inconsistent. The recent observational studies, randomized controlled trials, and meta-analyses are confirming that vitamin D or active vitamin D administration is effective in preventing the incident of type 1 and type 2 diabetes.
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Metadata
Title
Vitamin D efficacy in type 1 and type 2 diabetes
Authors
Tetsuya Kawahara
Yosuke Okada
Yoshiya Tanaka
Publication date
25-04-2024
Publisher
Springer Nature Singapore
Published in
Journal of Bone and Mineral Metabolism
Print ISSN: 0914-8779
Electronic ISSN: 1435-5604
DOI
https://doi.org/10.1007/s00774-024-01509-3
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