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Clinical Collections
Women’s Health Knowledge Hub Advances in Alzheimer’s

Navigating neuroimaging in Alzheimer disease care

PET imaging is playing an increasingly critical role in managing AD, but how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

This content is intended for healthcare professionals outside of the UK.
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Diabetes Type 1 Diabetes

Type 1 Diabetes

Long-term benefits for islet transplantation in type 1 diabetes

Islet transplantation alone significantly reduces the long-term risk for death and islet-after-kidney transplantation significantly reduces the long-term risk for dialysis in people with type 1 diabetes.

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Editor's Choice

Focus on insulin icodec

A thorough overview of the safety and efficacy of once-weekly basal insulin icodec in type 1 and 2 diabetes, covering pharmacology, pharmacokinetics, adverse effects, drug interactions, and dose recommendations.

Combining SGLT2is, GLP-1 RAs, and nsMRAs in diabetes

Combination therapy is a cornerstone of type 2 diabetes management, but what’s known about the effects of combining SGLT2 inhibitors, GLP-1 receptor agonists, and nonsteroidal MRAs?

Minimizing glycemic variability in type 1 diabetes

Recommendations proposed to reduce glycemic variability and improve glycemic management in people with type 1 diabetes, focusing on physical activity, dietary habits, insulin therapy, and other causes of increased variability.

Delayed diagnosis of monogenic diabetes

Complete heterozygous deletion of HNF1B was incidentally discovered in a woman who was enrolled in a clinical trial for type 1 diabetes and received immunosuppressive treatment for 4 years when she was a child.

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Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
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Podcast

Latest News

Long-term benefits for islet transplantation in type 1 diabetes

Hybrid closed loop delivery improves postpartum glycemic control in type 1 diabetes

Eating disorder treatment discrepancies between people with and without diabetes

More education needed to avoid ketoacidosis among young diabetes tech users

Significant improvements in pediatric glycemic control

Diabetes subtypes at diagnosis inform on patient-related outcomes

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by:
  • Abbott Diabetes Care
Prof. Samuel Seidu
Developed by: Adis
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Podcast

Case Studies

Delayed diagnosis of monogenic diabetes

Complete heterozygous deletion of HNF1B was incidentally discovered in a woman who was enrolled in a clinical trial for type 1 diabetes and received immunosuppressive treatment for 4 years when she was a child.

LADA and Graves disease preceded by minimal change nephrotic syndrome in childhood

A young woman diagnosed with minimal change nephrotic syndrome in childhood developed latent autoimmune diabetes in adults and Graves disease. HLA testing was performed to investigate her genetic background.

Stevens-Johnson syndrome/toxic epidermal necrolysis complicated with fulminant type 1 diabetes

A rare case of fulminant type 1 diabetes induced by SJS/TEN, which had developed in a patient taking carbamazepine and phenytoin. Glucose monitoring should be considered for patients with SJS/TEN.

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine
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Current Reviews

Advancing toward a curative frontier: an updated narrative review on stem-cell therapy in pediatric type 1 diabetes

Type 1 diabetes (T1D) remains one of the most prevalent chronic illnesses diagnosed in childhood, and is an immune-mediated disease directed against pancreatic β-cells, resulting in severe endogenous insulin deficiency and subsequent hyperglycemia …

The role of fecal microbiota transplantation in diabetes

Fecal microbiota transplantation (FMT) has emerged as a potential therapeutic strategy for modulating gut dysbiosis in diabetes mellitus. This review critically evaluates preclinical and clinical evidence on FMT in type 1 (T1D) and type 2 diabetes …

Cell Therapy for T1D Beyond BLA: Gearing Up Toward Clinical Practice

Type 1 diabetes (T1D) remains a significant global health challenge and patients with T1D need lifelong insulin therapy. Islet transplantation holds transformative potential by replacing autoimmune-mediated destruction of insulin-producing beta …

Urinary L-FABP: A Novel Biomarker for Evaluating Diabetic Nephropathy Onset and Progression. A Narrative Review

Patients with diabetes mellitus (DM) are at risk of developing diabetic nephropathy (DN), a condition whose onset and progression are linked to increased morbidity and mortality. Therefore, early recognition is crucial. Presently, this relies on …

Keynote webinar | Spotlight on diet and diabetes

  • On-demand Webinar

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Prof. Mike Lean
Prof. Falko Sniehotta
Developed by: Springer Medicine
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Video

CME & eLearning

News | Expert Reviews | Cases (Link opens in a new window)

Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany
Developed by: Springer Healthcare IME

Further Reading

Clustering of childhood acute leukemia in Finland: a nationwide register-based study

Acute leukemia is the most common malignancy in children, yet its etiology remains largely unknown. Several somatic changes are required for the development of leukemia, and according to a prevailing hypothesis, the first often occurs during fetal …

Severe hypoglycaemia is associated with increased risk of adverse cardiovascular complications in adults with type 1 diabetes: risk mitigation using intermittently scanned continuous glucose monitoring

Despite advances in glycaemic management, people with type 1 diabetes remain at higher risk of CVD and CVD-related mortality than people without diabetes [ 1 ]. Data from the Swedish National Diabetes Register (NDR) reveal that people with type 1 …

Lights and Shadows of Bariatric Surgery: Insights from a Nationwide Administrative Database of People Living with Type 1 Diabetes and Obesity

Contrary to historical teaching, it is now well established that people living with type 1 diabetes are not spared from suffering from overweight or obesity [ 1 ]. There is a worrying increase in the reported prevalence of overweight and obesity …

Metabolic effects of 3-hydroxybutyrate infusion in individuals with type 1 diabetes compared with healthy control participants: a randomised crossover trial showing intact feedback suppression of lipolysis

Diabetic ketoacidosis (DKA) is a consequence of absolute insulin deficiency and a potentially life-threatening complication in individuals with type 1 diabetes [ 1 ]. The insufficient insulin supply, accompanied by an increased concentration of …

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