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Advances in Therapy

Issue 5/2023

Content (41 Articles)

Open Access Fecal Incontinence Review

A Systematic Review of Epidemiology and Outcomes Associated with Local Surgical and Intersphincteric Ligation Procedures for Complex Cryptoglandular Fistulas

Kristy Iglay, Dimitri Bennett, Michael D. Kappelman, Xinruo Zhang, Molly Aldridge, Chitra Karki, Suzanne F. Cook

Review

Management of Older Patients with Head and Neck Cancer: A Comprehensive Review

Leandro L. Matos, Alvaro Sanabria, K. Thomas Robbins, Gyorgy B. Halmos, Primož Strojan, Wai Tong Ng, Robert P. Takes, Peter Angelos, Cesare Piazza, Remco de Bree, Ohad Ronen, Orlando Guntinas-Lichius, Avraham Eisbruch, Mark Zafereo, Antti A. Mäkitie, Ashok R. Shaha, Andres Coca-Pelaz, Alessandra Rinaldo, Nabil F. Saba, Oded Cohen, Fernando Lopez, Juan P. Rodrigo, Carl E. Silver, Timo E. Strandberg, Luiz Paulo Kowalski, Alfio Ferlito

Open Access Ulcerative Colitis Review

Epidemiological, Clinical, Patient-Reported and Economic Burden of Inflammatory Bowel Disease (Ulcerative colitis and Crohn’s disease) in Spain: A Systematic Review

Manuel Barreiro-de Acosta, Alberto Molero, Esther Artime, Silvia Díaz-Cerezo, Luis Lizán, Héctor David de Paz, María Dolores Martín-Arranz

Open Access Infliximab Review

Dose Escalation Patterns of Advanced Therapies in Crohn’s Disease and Ulcerative Colitis: A Systematic Literature Review

Remo Panaccione, Wan-Ju Lee, Ryan Clark, Kristina Kligys, Rhiannon I. Campden, Stacy Grieve, Tim Raine

Non-steroidal Anti-inflammatory Drugs: Clinical Implications, Renal Impairment Risks, and AKI

John M. LaForge, Kelsey Urso, Juan Martin Day, Cade W. Bourgeois, Maggie M. Ross, Shahab Ahmadzadeh, Sahar Shekoohi, Elyse M. Cornett, Adam M. Kaye, Alan David Kaye

Open Access Temperature Management Review

Temperature Control After Cardiac Arrest: A Narrative Review

Samantha Fernandez Hernandez, Brooke Barlow, Vera Pertsovskaya, Carolina B. Maciel

Open Access Infliximab Review

A Systematic Review of the Economic and Health-Related Quality of Life Impact of Advanced Therapies Used to Treat Moderate-to-Severe Ulcerative Colitis

Allie Cichewicz, Tom Tencer, Komal Gupte-Singh, Sonya Egodage, Heather Burnett, Jinender Kumar

Open Access Review

Safety Surveillance During Drug Development: Comparative Evaluation of Existing Regulations

Chrysanthi Samara, Alix Garcia, Christopher Henry, Laure Vallotton, Luca Cariolato, Jules Desmeules, Alexis Pinçon

NSCLC Original Research

Systematic Analysis of the Prognostic Significance and Roles of the Integrin Alpha Family in Non-Small Cell Lung Cancers

Yu Huang, Dong-Ming Guo, Shi Bu, Wei Xu, Qing-Chun Cai, Jian Xu, Yue-Quan Jiang, Fei Teng

Open Access Ezetimibe Original Research

A Bioequivalence Study of Ezetimibe/Rosuvastatin Fixed Dose Combination (10 mg/10 mg) Versus the Individual Formulations Taken Concomitantly

Yujing Di, Zhaojun Wang, Chuandong Jia, Xin Xie, Shanshan Yang, Wenhua Wang, Xiaochuan Xie, Qian Wang, Chanyan Hu, Fang Xie, Mohamed Abdel-Moneim, Lionel Hovsepian, Yanzhen Wu, Na Yang, Jie Hou

Multiple Sclerosis Original Research

A Prospective, Observational Study Assessing Effectiveness, Safety, and QoL of Greek Patients with Multiple Sclerosis Under Treatment with Fingolimod

Dimos D. Mitsikostas, Anastasios Orologas, Efthimios Dardiotis, Nikolaos Fakas, Triantafyllos Doskas, Klimentini Karageorgiou, Maria Maltezou, Ioannis Iliopoulos, Michail Vikelis, Nikolaos Grigoriadis

Open Access Original Research

Healthcare Service Use Patterns Among Patients with Acid Sphingomyelinase Deficiency Type B: A Retrospective US Claims Analysis

Ruth Pulikottil-Jacob, Michael L. Ganz, Marie Fournier, Natalia Petruski-Ivleva

Open Access Schizophrenia Original Research

Patient and Healthcare Professional Preferences for Characteristics of Long-Acting Injectable Antipsychotic Agents for the Treatment of Schizophrenia

Delbert G. Robinson, Mark Suett, Amanda Wilhelm, Nayla Chaijale, Kelli R. Franzenburg, Sanjay Gandhi, Blaine Cloud, Marko Mychaskiw

Open Access Mood Disorders Original Research

Treatment Patterns Among Patients with Attention-Deficit/Hyperactivity Disorder and Comorbid Anxiety and/or Depression in the United States: A Retrospective Claims Analysis

Jeff Schein, Ann Childress, Patrick Gagnon-Sanschagrin, Jessica Maitland, Jerome Bedard, Martin Cloutier, Annie Guérin

Open Access Diuretics Original Research

Real-World Effectiveness and Safety of Two-Drug Single Pill Combinations of Antihypertensive Medications for Blood Pressure Management: A Follow-Up on Daily Cardiology Practice in Douala, Cameroon

Anastase Dzudie, Blaise Barche, Franck Zomene, Peter Vanes Ebasone, Clovis Nkoke, Sidick Mouliom, Djibrilla Sidikatou, Viche Lade, Henri Ngote, Yacouba Mapoure Njankouo, Bertrand Hugo Mbatchou, Felicite Kamdem, Jules Njebet, Andre Pascal Kengne, Simeon Pierre Choukem

Open Access Muscular Dystrophy Original Research

Concept Elicitation Interviews and Conceptual Model to Understand the Patient Experience of Limb Girdle Muscular Dystrophy

Kelly Johnston, Cristina Casstevens, Vanessa Perez Patel, Elizabeth Merikle, Carrie Presnall, Ivana Audhya

Open Access Crohn's Disease Original Research

Efficacy, Safety, Patient Experience, and Tolerability of Risankizumab Administered by On-Body Injector for Moderate to Severe Crohn’s Disease

Edward V. Loftus Jr., Jenny Griffith, Ezequiel Neimark, Alexandra Song, Kori Wallace, Sujani Nannapaneni, Ji Zhou, Rachel Byrne, Kristina Kligys, Yinuo Pang, Xiaomei Liao, Jasmina Kalabic, Marla Dubinsky

Open Access Lymphoma Original Research

Cost-Effectiveness of Brentuximab Vedotin Versus Physician’s Choice of Methotrexate or Bexarotene for the Treatment of Cutaneous T-cell Lymphoma in Canada

David Elsea, Kerry J. Savage, Cameron Lilley, Julie Lisano, Jingmin Liu, Kristina S. Yu

Open Access Stroke Original Research

Ischemic Stroke and Systemic Embolism Among One-and-Done Direct Oral Anticoagulant Users with Non-valvular Atrial Fibrillation

Mark Alberts, Maryia Zhdanava, Dominic Pilon, Gabrielle Caron-Lapointe, Patrick Lefebvre, Brahim Bookhart, Akshay Kharat

Open Access Lymphoma Original Research

Cost-Effectiveness of Lisocabtagene Maraleucel Versus Axicabtagene Ciloleucel and Tisagenlecleucel in the Third-Line or Later Treatment Setting for Relapsed or Refractory Large B-cell Lymphoma in the United States

Christopher Parker, Fei Fei Liu, Kristen A. Deger, Conrado Franco-Villalobos, Irina Proskorovsky, Scott J. Keating, Sonja Sorensen

Open Access Pigmentary Retinopathy Original Research

Quality of Life and Economic Impacts of Retinitis Pigmentosa on Japanese Patients: A Non-interventional Cross-sectional Study

Katsuhiko Watanabe, Celia Aouadj, Yoshimune Hiratsuka, Shuichi Yamamoto, Akira Murakami

Open Access Original Research

Interview-Based Patient- and Caregiver-Reported Experiences of Hunger and Improved Quality of Life with Setmelanotide Treatment in Bardet-Biedl Syndrome

Claire Ervin, Lindsey Norcross, Usha G. Mallya, Sheri Fehnel, Robert S. Mittleman, Matthew Webster, Andrea M. Haqq, Robert M. Haws

Open Access Multiple Myeloma Original Research

Comparative Efficacy of Teclistamab Versus Current Treatments in Real-World Clinical Practice in the Prospective LocoMMotion Study in Patients with Triple-Class-Exposed Relapsed and/or Refractory Multiple Myeloma

Philippe Moreau, Niels W. C. J. van de Donk, Michel Delforge, Hermann Einsele, Valerio De Stefano, Aurore Perrot, Britta Besemer, Charlotte Pawlyn, Lionel Karlin, Salomon Manier, Xavier Leleu, Katja Weisel, Francesca Ghilotti, Joris Diels, Ahmed Elsada, Raul Morano, Vadim Strulev, Lixia Pei, Rachel Kobos, Jennifer Smit, Mary Slavcev, Maria-Victoria Mateos

Open Access Ustekinumab Original Research

Genetic and Molecular Distinctions Between Axial Psoriatic Arthritis and Radiographic Axial Spondyloarthritis: Post Hoc Analyses from Four Phase 3 Clinical Trials

Arthur Kavanaugh, Xenofon Baraliakos, Sheng Gao, Warner Chen, Kristen Sweet, Soumya D. Chakravarty, Qingxuan Song, May Shawi, Proton Rahman

Open Access Achondroplasia Original Research

Parents’ Experience of Administering Vosoritide: A Daily Injectable for Children with Achondroplasia

Sinead NiMhurchadha, Karen Butler, Rob Argent, Katja Palm, Genevieve Baujat, Valerie Cormier-Daire, Klaus Mohnike

ß-Blockers Original Research

Type 2 Myocardial Infarction and Long-Term Mortality Risk Factors: A Retrospective Cohort Study

Rokas Šerpytis, Mindaugas Lizaitis, Egle Majauskienė, Petras Navickas, Sigita Glaveckaitė, Žaneta Petrulionienė, Nomeda Valevičienė, Aleksandras Laucevičius, Qin M. Chen, Joseph S. Alpert, Pranas Šerpytis

Plaque Psoriasis Brief Report

The Effectiveness of Guselkumab by BMI Category Among Patients with Moderate-to-Severe Plaque Psoriasis in the CorEvitas Psoriasis Registry

April W. Armstrong, Timothy Fitzgerald, Robert R. McLean, Amanda Teeple, Jonathan P. Uy, Mobolaji Olurinde, Katelyn Rowland, Lin Guo, Ying Shan, Kristina Callis Duffin

Open Access Atopic Dermatitis Brief Report

Real-Life Effectiveness and Tolerance of Upadacitinib for Severe Atopic Dermatitis in Adolescents and Adults

Axel De Greef, Pierre-Dominique Ghislain, Laurence de Montjoye, Marie Baeck

Open Access Breast Cancer Brief Report

Characteristics and Outcomes in Cases of US Male Patients with Metastatic Breast Cancer Receiving Abemaciclib in Routine Clinical Practice

Alistair Ring, Meghan Karuturi, Emily Nash Smyth, Tasneem Lokhandwala, Kristin M. Sheffield, Joanne Willey, Orsolya Lunacsek, Francisco Sapunar, Zhanglin Lin Cui, Anna Coutinho, Sarah Rybowski

Propofol Study Protocol

Study Protocol of a Multicenter, Randomized, Single-Blind Trial: Efficacy and Safety of Remimazolam Tosylate for Sedation in ICU Patients

Ning Liu, Zhiyi Jiang, Yao Nie, Lingyun Zuo, Chuanxi Chen, Xiang Si, Qin Liu, Minying Chen, Xiangdong Guan

Human Uterine Lavage: First Live Births from In Vivo Conceived Genetically Screened Blastocysts

Sam Najmabadi, José L. Rivas, Marlane J. Angle, Alexander Nadal, Ercan Bastu, Santiago Munné, Sandra A. Carson, John E. Buster, Steven T. Nakajima

Open Access Umeclidinium Letter

A Response to: Letter to the Editor Regarding “Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Triple Therapy Compared with Other Therapies for the Treatment of COPD: A Network Meta-analysis”

Afisi S. Ismaila, Katrin Haeussler, Mia Malmenäs, Raj Sharma, Chris Compton, Claus F. Vogelmeier, MeiLan K. Han, David M. G. Halpin

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.