The delayed titration of guideline-directed medical therapy is complex and often results in poor prognosis for heart failure patients. Are you using GDMT in the most effective way?
Learn about Fabry disease, a rare disease that can have renal, cardiovascular, neurological, cutaneous, and ophthalmic manifestations. Discover the ways in which it may be possible to personalize treatment.
The risks of ischemic and hemorrhagicstroke and poor neurological outcomes after stroke are increased in people with type 2 diabetes. Explore how to manage the hyperacute stroke stage and prevent CV disease.
Guidelines from the Pediatric Renal Nutrition Taskforce advise on assessing and managing vitamin deficiency or excess in children with chronic kidney disease stages 2–5, on dialysis and post-transplantation.
New computerized clinical decision support system could help primary care physicians improve hypertension control in people with chronic kidney disease.
Major adverse kidney events occur within 90 days in nearly two thirds of children, adolescents, and young adults after initiation of continuous kidney replacement therapy.
Kidney injury is a known side-effect of using adalimumab to treat inflammatory bowel diseases, but has rarely been seen in children. Timely withdrawal can significantly reduce kidney damage but it is irreversible in some cases.
Cefepime–taniborbactam combination treatment might be a better option than meropenem for complicated urinary tract infections and acute pyelonephritis.
Cardiovascular outcome trials indicate that incretin-based therapies have renal benefits beyond their glucose-lowering efficacy. But what is the evidence regarding the nephroprotective effects of these anti-diabetes compounds?
Better biomarkers are needed to diagnose UTI, which is one of the most prevalent childhood bacterial infections. Blood procalcitonin and urinary neutrophil gelatinase-associated lipocalin look promising.
UTIs are common in people with diabetes, but how do they compare with UTIs in people without diabetes? And what role might SGLT2 inhibitors have in the increased risk of genitourinary infections?
Changing to a ciclosporin-based regimen resolved the signs and symptoms of hepatitis in a patient who presented with icterus, weakness, and lethargy two weeks after kidney transplantation and initiation of tacrolimus.
Using cystatin C as well as creatinine measurements improves estimated glomerular filtration rate calculations when staging chronic kidney disease in older adults.
Several retrospective and prospective studies have evaluated the outcomes of planned discontinuation of tyrosine kinase inhibitors in patients with renal cell carcinoma, and the strategy appears to be viable.
Aggressive lifestyle modifications alongside antihypertensive therapy is an effective treatment strategy for controlling hypertension. But what effect does a low-sodium, high-potassium diet have on broader CV events?
Older women who require dialysis have an increased risk for severe hypocalcemia if they initiate treatment for osteoporosis with denosumab rather than oral bisphosphonates.
Explore the proposed connection between hyperuricemia and metabolic syndrome, diabetes mellitus, chronic kidney disease, including end-stage renal disease, the post-transplant population, and hypertension.
Growing evidence shows that lack of readiness for the transition from pediatric to adult healthcare increases morbidity and mortality in patients with chronic kidney disease and reduces allograft survival in transplanted patients.
Low blood sodium levels associated with new thiazide diuretic use for uncomplicated hypertension may occur more frequently than is indicated by drug prescribing information.
Screening rates for primary aldosteronism among at-risk patients with hypertension can be improved by implementing a best-practice advisory in electronic health records that prompts physicians to order the relevant tests.
