Dapagliflozin significantly reduces the urine albumin-to-creatinine ratio versus placebo in people with type 2 diabetes and chronic kidney disease, but the magnitude of the effect varies per person.
Combination therapy is a cornerstone of type 2 diabetes management, but what’s known about the effects of combining SGLT2 inhibitors, GLP-1 receptor agonists, and nonsteroidal MRAs?
Clinical signs of cardiac congestion can be subtle. This review walks you through essential imaging techniques to identify congestion, clarify its origin, and guide the management of cardiorenal syndrome.
Three years is the minimum duration of sustained clinical remission needed to protect patients with lupus nephritis against impaired kidney function and damage accrual.
Dual SGLT1/2 inhibitor sotagliflozin significantly reduces major adverse cardiac events, including myocardial infarction and stroke, in people with type 2 diabetes, CKD, and high CV risk.
AIP can easily be overlooked in its early stages. When a patient presents with central, peripheral, or autonomic nervous system symptoms and common causes are ruled out, AIP should be considered.
An in-depth analysis of the epidemiology, diagnosis, treatment options, outcomes, and survival of pediatric renal tumors, such as Wilms tumor, renal clear cell sarcoma, and malignant rhabdoid tumor.
A neoantigen-targeting personalized cancer vaccine has shown promising antitumor activity in people with high-risk, fully resected renal cell carcinoma.
Myocardial amyloidosis is often missed in the early stages. Understand the importance of multimodal imaging in diagnosing systemic AL amyloidosis, particularly when patients present with extra-cardiac symptoms.
Post-surgical acute kidney injury is common after cardiac procedures. Despite some understanding of the mechanisms, there remains no effective treatment for prevention or management. Might new therapies in early clinical trials be the solution?
Evidence is mounting for the significant association between metabolic dysfunction associated-steatotic liver disease and cardiovascular disease. Understand the specific relationships between MASLD and heart failure, atrial fibrillation, stroke, and peripheral artery disease.
A young woman diagnosed with minimal change nephrotic syndrome in childhood developed latent autoimmune diabetes in adults and Graves disease. HLA testing was performed to investigate her genetic background.
Biliary and peribiliary cystic lesions are often discovered incidentally during imaging for unrelated conditions. Although typically asymptomatic, precise imaging is needed to characterize their nature and determine next steps.
Reninoma should be considered in young people with hypokalemic hypertension when common causes have been excluded. Excision can cure hypertension and prevent morbidity and mortality.
CPS are genetic disorders that significantly increase the risk of developing malignancies. The malignant features of CPS are well-studied, but recognizing their non-malignant features is crucial for early diagnosis in children and adolescents.
Urate-lowering therapy to below 6 mg/dL in people with gout and chronic kidney disease does not increase the risks for kidney disease progressing to severe or end-stage.
A patient with pancreatogenic diabetes developed life-threatening euglycemic ketoacidosis following re-exposure to an SGLT2 inhibitor and alcohol excess. Early renal replacement therapy was successful.
Hemodiafiltration is associated with significantly better survival rates than hemodialysis among people with kidney failure, with significant reductions in both all-cause and cardiovascular mortality.
