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Toxic Hepatitis 

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  1. 01-12-2021 | OriginalPaper

    Monooxygenase System and NO Metabolism in Liver Microsomes of Rats with Toxic Hepatitis and the Effect of Sesquiterpene Lactones

    We analyzed changes in activities of enzymes of phases I and II of xenobiotic biotransformation and parameters of NO metabolism in liver microsomes of rats with toxic CCl4-induced hepatitis after a 14-day course of sesquiterpene lactones from …

  2. 01-03-2019 | OriginalPaper

    Treat autoimmune hepatitis in the elderly with corticosteroids + azathioprine to reduce the risk of corticosteroid-related toxicity

    Autoimmune hepatitis (AIH) is an autoreactive chronic inflammatory liver disease that can affect individuals of any age. In the elderly, AIH may present as acute or chronic hepatitis with elevated liver enzyme levels. As elderly patients have …

  3. 01-07-2016 | OriginalPaper

    Acute interstitial nephritis, toxic hepatitis and toxic myocarditis following multiple Asian giant hornet stings in Shaanxi Province, China

    Wasps are found almost in all parts of the world. They play an important role in the balance of natural ecosystems through pollination, natural pest control and biodiversity [ 1 , 2 ]. So far, over 30,000 species have been identified [ 3 ]. The …

  4. 01-12-2003 | OriginalPaper

    Toxic hepatitis secondary to oral administration of exemestane

    Los inhibidores de aromatasa se prescriben a pacientes con cáncer de mama que han progresado tras la administración de tamoxifeno. Los efectos adversos son mínimos o moderados y de fácil manejo.De acuerdo con lo publicado hasta la fecha, ésta es …

  5. 01-05-2009 | Report

    Conjugated Linoleic Acid-Induced Toxic Hepatitis: First Case Report

    A 46-year-old female patient was referred to our department with presenting symptoms of asthenia, jaundice, and pruritus. There was no medical history or clinical evidence of viral hepatitis, autoimmune hepatitis, hemochromatosis, or Wilson’s …

  6. 01-07-2008 | OriginalPaper

    Hepatoprotective properties of fractions from meadowsweet extract during experimental toxic hepatitis

    Fractions of the extract from meadowsweet aerial parts in 70% ethanol exhibited hepatoprotective properties during CCl4-induced toxic hepatitis. This extract produced a normalizing effect on activity of enzymes, markers of cytolysis, lipid …

  7. 01-08-2006 | OriginalPaper

    Hepatoprotective and antioxidant activity of meadowsweet extract during experimental toxic hepatitis

    The extract of meadowsweet aerial parts exhibits hepatoprotective and antioxidant activity during experimental toxic CCl4 hepatitis. This extract improved liver function. Meadowsweet extract in 70% ethanol (100 mg/kg) was most potent and exhibited …

  8. 01-01-2011 | OriginalPaper

    Liver enzyme abnormalities in systemic lupus erythematosus: a focus on toxic hepatitis

    Although subclinical liver disease is common in systemic lupus erythematosus (SLE), strikingly high levels of liver enzymes are rare. Our aim was to determine the cause of high levels of liver enzymes in lupus patients, particularly in patients …

  9. 01-11-2008 | OriginalPaper

    Pro- and Antioxidants in the Central Lymph in Experimental Chronic Toxic Hepatitis

    Using rat model of chronic toxic hepatitis we showed the involvement of the lymph system in the formation of the response to toxic liver damage consisting in deposition of LPO products in the central lymph and active involvement of antioxidants in …

  10. 01-05-2001 | OriginalPaper

    Hepatoprotective Properties of Aqueous Extract from Pentaphylloides fruticosa during Chronic Toxic Hepatitis

    Hepatoprotective properties of Pentaphylloides fruticosa L. aqueous extract were studied using rat model of chronic toxic hepatitis. The preparation normalized alanine aminotransferase activity and bilirubin concentration in the plasma. Aqueous …

  11. 01-12-2008 | OriginalPaper

    Functional Activity of Sphingomyelin Cycle in Rat Liver in Chronic Toxic Hepatitis

    Activities of sphingomyelinase and ceramidase decreased in the liver in chronic toxic hepatitis and the balance between the levels of proapoptotic ceramide and antiapoptotic sphyngosine-1-phosphate shifts towards the latter substance. Pronounced …

  12. 01-03-2004 | BriefCommunication

    CASE REPORT: Toxic Hepatitis After Sequential Administration of Flutamide and Cyproterone Acetate

  13. 01-10-2015 | OriginalPaper

    Prospective analysis of tiopronin in prevention of sorafenib and antiviral therapy inducing liver toxicity in advanced hepatitis B virus-related hepatocellular carcinoma

    Hepatotoxicity induced by sorafenib and antiviral therapy is a limitation for its continuation treatment for patients with advanced hepatitis B virus-related hepatocellular carcinoma (HCC). This prospective study determined the efficacy of …

  14. 01-03-2000 | OriginalPaper

    Hepatoprotective properties of soybean proteins and their use for dietary therapy of chronic toxic hepatitis

    Hepatoprotective effect of a diet containing soybean proteins most pronounced in soybean milk was demonstrated on the model of chronic toxic hepatitis. Results of biochemical studies correlate with morphological data indicating that soybean …

  15. 01-10-2009 | OriginalPaper

    Effect of N-[Imino(4-morpholyl)methyl]guanidine on the Oxidative Status in Rats with Toxic Hepatitis

    The hepatoprotective and antioxidant properties of a synthetic biguanide N-[imino(4-morpholyl) methyl]guanidine (IMMG) were prognosticated by the method of computer prediction. Administration of IMMG was accompanied by a decrease in serum …

  16. 01-01-2003 | OriginalPaper

    Effects of Homeopathic Preparations on the Liver in Rats with Acute and Chronic Toxic Hepatitis

    Ultralow doses of antibodies to phenobarbital and their mixture (1:1) with ultralow doses of antibodies to cholecystokinin reduced the severity of structural and metabolic disturbances in the liver of rats with acute CCl4-induced hepatitis. The …

  17. 01-07-2010 | OriginalPaper

    Reduction in Neutrophil Count During Hepatitis C Treatment: Drug Toxicity or Predictor of Good Response?

    Chronic hepatitis C virus (HCV) infection is a common disease worldwide and is associated with liver cirrhosis and hepatocellular carcinoma [ 1 ]. Treatment with peginterferon and ribavirin achieves sustained virological response (SVR) in 40–80% of …

  18. 01-08-2012 | OriginalPaper

    Protective Effect of Transplantation of Neonatal Liver Cell Nuclei on the Model of Acute Toxic Hepatitis

    We present the results of comparative analysis of functional and morphological changes in the liver of animals with experimental CCl4-induced hepatitis under conditions of transplantation of neonatal liver cells and nuclei. It was found that …

  19. 01-09-1998 | Letter

    Acute hepatitis in a patient treated with saquinavir and ritonavir: Absence of cross-toxicity with indinavir

  20. 01-10-2012 | OriginalPaper

    Effect of Triterpene Derivatives on the Total Hepatocyte Count in the Liver of Rats with Toxic Hepatitis

    We studied hepatoprotective activity of betulonic acid and its alaninamide on the model of combined CCl4- and ethanol-induced toxic liver damage in rats. The test substances, especially betulonic acid alaninamide, considerably reduced the elevated …

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