Kidney injury is a known side-effect of using adalimumab to treat inflammatory bowel diseases, but has rarely been seen in children. Timely withdrawal can significantly reduce kidney damage but it is irreversible in some cases.
Changing to a ciclosporin-based regimen resolved the signs and symptoms of hepatitis in a patient who presented with icterus, weakness, and lethargy two weeks after kidney transplantation and initiation of tacrolimus.
A case of treatment-resistant hyperparathyroidism with severe complications in a long-term kidney dialysis patient, who presented with an atypically located adenoma that required comprehensive surgical intervention.
A panel of experts examine the differential diagnosis for secondary hypertension in a young child, and the eventual diagnosis and management of generalized arterial calcification in infants.
This case indicates that capillary blood glucose monitoring should be used alongside intermittently scanned CGM when pregnancy is complicated by type 1 diabetes and CKD.
Metformin-associated lactic acidosis can cause acute blindness, but vision may be recovered by timely treatment of acidosis. Physicians should be aware that even if patients have severe metabolic acidosis they can still have stable vital signs.
Multiple masses in a transplanted kidney raise suspicion for malignancy, but this case demonstrates the importance of a broad differential diagnosis and biopsy, which instead detected a serious infection.
A patient with urinary bladder myeloid sarcoma as the presenting feature of secondary acute myeloid leukemia responded well to treatment with azacitidine and venetoclax.
A patient with left-dominant heart failure was diagnosed with bilateral primary aldosteronism. Hypertension persisted despite treatment with antihypertensive drugs, but heart failure improved after unilateral adrenalectomy.
Diabetic ketoacidosis and a hyperglycemic hyperosmolar state were induced by severe diarrhea in a kidney transplant recipient due to a Paxlovid–tacrolimus drug–drug interaction.
CPM is a rare but potentially fatal neurological condition. This case highlights the development of CPM in a patient with uncontrolled diabetes as a consequence of hyperosmolar hyperglycemia.
