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Published in: Hepatology International 4/2023

Open Access 15-05-2023 | Obesity | Editorial

Obesity and non-alcoholic steatohepatitis in immunotherapy for hepatocellular carcinoma

Authors: Shuichiro Shiina, Hitoshi Maruyama, Maki Tobari, Tatsuya Yamashita

Published in: Hepatology International | Issue 4/2023

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Excerpt

The atezolizumab plus bevacizumab combination therapy (Atezo/Beva) opened the door to immunotherapy for unresectable hepatocellular carcinoma (HCC) [1]. Following Atezo/Beva, three other combination immunotherapies, sintilimab plus a bevacizumab biosimilar (ORIENT-32) [2], tremelimumab plus durvalumab (HIMALAYA) [3], atezolizumab plus cabozantinib (COSMIC-312) [4], have shown survival benefits as first line systemic therapy for unresectable HCC. Systemic therapy for HCC is shifting toward immunotherapy. …
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Metadata
Title
Obesity and non-alcoholic steatohepatitis in immunotherapy for hepatocellular carcinoma
Authors
Shuichiro Shiina
Hitoshi Maruyama
Maki Tobari
Tatsuya Yamashita
Publication date
15-05-2023
Publisher
Springer India
Published in
Hepatology International / Issue 4/2023
Print ISSN: 1936-0533
Electronic ISSN: 1936-0541
DOI
https://doi.org/10.1007/s12072-023-10533-w

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