Issue 1/2017
Content (32 Articles)
Dabrafenib and trametinib activity in a patient with BRAF V600E mutated and microsatellite instability high (MSI-H) metastatic endometrial cancer
- Open Access
- Case report
Michele Moschetta, Gabriel Mak, Joana Hauser, Catriona Davies, Mario Uccello, Hendrik-Tobias Arkenau
Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche
- Open Access
- Research
Natalia-Del Pilar Vanegas, Jean-Paul Vernot
Molecular classification of tissue from a transformed non-Hogkin’s lymphoma case with unexpected long-time remission
- Open Access
- Case report
Julie Støve Bødker, Marianne Tang Severinsen, Tarec Christoffer El-Galaly, Rasmus Froberg Brøndum, Maria Bach Laursen, Steffen Falgreen, Mette Nyegaard, Alexander Schmitz, Lasse Hjort Jakobsen, Anna Amanda Schönherz, Hanne Due, Linn Reinholdt, Martin Bøgsted, Karen Dybkær, Hans Erik Johnsen
Atypical hemolytic uremic syndrome in first trimester pregnancy successfully treated with eculizumab
- Open Access
- Case report
Gabriela Andries, Michael Karass, Srikanth Yandrapalli, Katherine Linder, Delong Liu, John Nelson, Rahul Pawar, Savneek Chugh
A randomized exploratory phase 2 study in patients with chemotherapy-related peripheral neuropathy evaluating whole-body vibration training as adjunct to an integrated program including massage, passive mobilization and physical exercises
- Open Access
- Research
Stefan S. Schönsteiner, Heidi Bauder Mißbach, Axel Benner, Silja Mack, Thomas Hamel, Michael Orth, Bernhard Landwehrmeyer, Sigurd D. Süßmuth, Carolin Geitner, Regine Mayer-Steinacker, Anneliese Riester, Andrea Prokein, Elfriede Erhardt, Jelena Kunecki, Anna M. Eisenschink, Rainer Rawer, Hartmut Döhner, Elisabeth Kirchner, Richard F. Schlenk
Metastatic BRAF K601E-mutated melanoma reaches complete response to MEK inhibitor trametinib administered for over 36 months
- Open Access
- Case report
Riccardo Marconcini, Luca Galli, Andrea Antonuzzo, Simona Bursi, Claudia Roncella, Gabriella Fontanini, Elisa Sensi, Alfredo Falcone
nab-Paclitaxel for the treatment of breast cancer: an update across treatment settings
- Open Access
- Review
Adam Brufsky
Acquired factor VIII deficiency: two case reports and a review of literature
- Open Access
- Case report
Lan Mo, George C. Bao
Adult acute precursor B-cell lymphoblastic leukemia presenting as hypercalcemia and osteolytic bone lesions
- Open Access
- Case report
Nikki Charlotta Paul Granacher, Zwi N. Berneman, Wilfried Schroyens, Ann L. R. Van de Velde, Anke Verlinden, Alain P. A. Gadisseur
Advances of CD19-directed chimeric antigen receptor-modified T cells in refractory/relapsed acute lymphoblastic leukemia
- Open Access
- Review
Guoqing Wei, Lijuan Ding, Jiasheng Wang, Yongxian Hu, He Huang
Metastatic squamous cell carcinoma of colon from esophageal cancer
- Open Access
- Case report
Natasha Garg, Constance Stoehr, Yan Shi Zhao, Heather Rojas, Chung-Tsen Hsueh
The development of bispecific antibodies and their applications in tumor immune escape
- Open Access
- Review
Xiaolong Zhang, Yuanyuan Yang, Dongmei Fan, Dongsheng Xiong
Cyclosporine is a potential curative treatment option for advanced thymoma
- Open Access
- Case report
Yusuke Isshiki, Hiroaki Tanaka, Yoshio Suzuki, Yukihiro Yoshida
Changes in clinical laboratory parameters and pharmacodynamic markers in response to blinatumomab treatment of patients with relapsed/refractory ALL
- Open Access
- Research
Virginie Nägele, Andrea Kratzer, Gerhard Zugmaier, Chris Holland, Youssef Hijazi, Max S. Topp, Nicola Gökbuget, Patrick A. Baeuerle, Peter Kufer, Andreas Wolf, Matthias Klinger
In vivo and in situ programming of tumor immunity by combining oncolytics and PD-1 immune checkpoint blockade
- Open Access
- Letter to the Editor
Eric Bartee, Zihai Li
Clinical implications of c-maf expression in plasma cells from patients with multiple myeloma
- Open Access
- Research
GuoQing Wei, LiJun Wang, HanJin Yang, XiaoYan Han, GaoFeng Zheng, WeiYan Zheng, Jie Sun, JiMin Shi, WenJun Wu, Yi Zhao, DongHua He, Bo Wang, Zhen Cai, JingSong He
Low-dose methotrexate in sickle-cell disease: a pilot study with rationale borrowed from rheumatoid arthritis
- Open Access
- Research
Silvia R. Brandalise, Rosemary Assis, Angelo B. A. Laranjeira, José Andrés Yunes, Pedro O. de Campos-Lima
PTEN is a negative regulator of mitotic checkpoint complex during the cell cycle
- Open Access
- Research
Byeong H. Choi, Steve Xie, Wei Dai
Interferon-alpha-based immunotherapies in the treatment of B cell-derived hematologic neoplasms in today’s treat-to-target era
- Open Access
- Review
Li Zhang, Yu-Tzu Tai, Matthew Zhi Guang Ho, Lugui Qiu, Kenneth C. Anderson
Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature
- Open Access
- Case report
Daniel E. Ezekwudo, Rebecca Chacko, Bolanle Gbadamosi, Syeda Batool, Sussana Gaikazian, Theodore E. Warkentin, Jo-Ann I. Sheppard, Ishmael Jaiyesimi
Microfluidic device for primary tumor spheroid isolation
- Open Access
- Short report
Jiaojiao Zhou, Jimmy Su, Xiaotong Fu, Lei Zheng, Zhizhong Yin
Pivotal regulators of tissue homeostasis and cancer: macrophages
- Open Access
- Review
Yulei Chen, Xiaobo Zhang
Optimizing peripheral blood stem cells transplantation outcome through amend relapse and graft failure: a review of current literature
- Open Access
- Review
Saeed Mohammadi, Amir Hossein Norooznezhad, Ashraf Malek Mohammadi, Hajar Nasiri, Mohsen Nikbakht, Najmaldin Saki, Mohammad Vaezi, Kamran Alimoghaddam, Ardeshir Ghavamzadeh
Complete biochemical response after pulmonary metastasectomy in prostate adenocarcinoma
- Open Access
- Case report
Jonathan Rush, Reet Pai, Rahul A. Parikh
Post-transplant lymphoproliferative disorder (PTLD): single institutional experience of 141 patients
- Open Access
- Research
Rohit Bishnoi, Ravneet Bajwa, Aaron J. Franke, William Paul Skelton IV, Yu Wang, Niraj M. Patel, William Birdsall Slayton, Fei Zou, Nam H. Dang
Pharmacokinetics of carfilzomib in patients with advanced malignancies and varying degrees of hepatic impairment: an open-label, single-arm, phase 1 study
- Open Access
- Research
Jennifer Brown, Ruth Plummer, Todd M. Bauer, Stephen Anthony, John Sarantopoulos, Filip De Vos, Mike White, Marco Schupp, Ying Ou, Ulka Vaishampayan
Incorporation of functional elements enhances the antitumor capacity of CAR T cells
- Open Access
- Review
Le Qin, Ruocong Zhao, Peng Li
Extraordinary clinical benefit to sequential treatment with targeted therapy and immunotherapy of a BRAF V600E and PD-L1 positive metastatic lung adenocarcinoma
- Open Access
- Case report
Shuyu D. Li, Annia Martial, Alexa B. Schrock, Jane J. Liu
Histomorphological responses after therapy with pegylated interferon α-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV)
- Open Access
- Research
Lucia Masarova, C. Cameron Yin, Jorge E. Cortes, Marina Konopleva, Gautam Borthakur, Kate J. Newberry, Hagop M. Kantarjian, Carlos E. Bueso-Ramos, Srdan Verstovsek
Development and clinical application of anti-HER2 monoclonal and bispecific antibodies for cancer treatment
- Open Access
- Review
Shengnan Yu, Qian Liu, Xinwei Han, Shuang Qin, Weiheng Zhao, Anping Li, Kongming Wu
Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis
- Open Access
- Case report
Mauricio Sarmiento Maldonado, Pablo Ramírez Villanueva, Pablo Bertín Cortes-Monroy, Veronica Jara Arias, Katherine Soto Donoso, Pablo Uribe Gonzalez, Mauricio Ocqueteau Tachini, Jose Antonio Perez-Simón