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Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Venous Disease
Open Access Interstitial Lung Disease and Pulmonary Fibrosis Review

Managing the VTE risk in patients with CTD-ILD

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People with connective tissue disease-related interstitial lung disease have an increased risk for developing venous thromboembolisms. What risk factors do clinicians need to be aware of?

Editor's Choice

Delivering ECMO despite jugular vein thrombosis

Open Access Venous Thrombosis Case Study

A patient with aspiration pneumonia-induced ARDS required  venovenous ECMO cannulation, but presented with multiple thrombi in the internal jugular veins which limited access. VV-ECMO was alternatively established using the right axillary vein as the access site.

Acute vena cava thrombosis leading to obstructive shock

Open Access Venous Thrombosis Case Study

Following an orthopedic trauma and DVT, a patient received an inferior vena cava filter intended to prevent pulmonary embolism. However obstructive shock developed secondary to extensive inferior vena cava thrombosis caused by inadequate anticoagulant therapy. 

Osteomyelitis as an underlying cause of deep vein thrombophlebitis

Open Access Osteomyelitis Case Study

Septic pulmonary embolism, deep vein thrombophlebitis, and acute osteomyelitis form a triad that is usually associated with trauma on long bones, but diagnosis is frequently delayed, risking life-threatening complications.

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Latest News

No reduction in VTE risk with apixaban in pediatric patients with ALL, LBL

01-12-2023 Acute Lymphoblastic Leukemia News

Extended anticoagulation for cancer patients with isolated distal DVTs

31-08-2023 Venous Thrombosis News

Cancer treatment linked to increased risk for COVID-19-related VTE

30-08-2023 Cancer Therapy News

ART does not increase maternal CV risk

29-08-2023 Circulatory Disease News

ESMO guideline on VTE prevention, treatment now available

13-01-2023 Venous Thrombosis News
Hypertension Podcast

Episode 3: Unravelling resistant hypertension

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Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Delivering ECMO despite jugular vein thrombosis

Open Access Venous Thrombosis Case Study

A patient with aspiration pneumonia-induced ARDS required  venovenous ECMO cannulation, but presented with multiple thrombi in the internal jugular veins which limited access. VV-ECMO was alternatively established using the right axillary vein as the access site.

DVT: an unusual sign of pediatric scurvy

Open Access Metabolic Disease in Childhood Case Study

Signs of scurvy are non-specific and wide ranging, so vitamin C deficiency is often misdiagnosed. This is the first case of DVT caused by large pelvic subperiosteal hematomas in an autistic boy with severe dietary restriction.

Acute vena cava thrombosis leading to obstructive shock

Open Access Venous Thrombosis Case Study

Following an orthopedic trauma and DVT, a patient received an inferior vena cava filter intended to prevent pulmonary embolism. However obstructive shock developed secondary to extensive inferior vena cava thrombosis caused by inadequate anticoagulant therapy. 

Current Reviews

Venous Thrombosis in Acute Pancreatitis: What to and Not to Do?

Acute Pancreatitis Invited Reviews

Acute pancreatitis is an acute inflammatory condition of the pancreas that has not only local but systemic effects as well. Venous thrombosis is one such complication which can give rise to thrombosis of the peripheral vasculature in the form of …

Skin Grafting for Dermatologists: Past, Present, and Future

Open Access Skin Graft REVIEW

Skin grafting is a surgical technique used to replace damaged or missing skin with healthy skin. This procedure is commonly used in various medical fields, including dermatology, plastic surgery, and burn care. The primary objective of skin …

Systemic Disease and Portal Hypertension

Portal Hypertension Review

Most cases of portal hypertension are related to sinusoidal portal hypertension caused by cirrhosis from primary liver diseases or systemic diseases [ 1 , 2 ]. Complications from portal hypertension include bleeding from gastroesophageal and …

Platelet-rich plasma therapy for chronic cutaneous wounds stratified by etiology: a systematic review of randomized clinical trials

Open Access Venous Leg Ulcer Systematic Review

Chronic wounds are cutaneous wounds that do not heal or require a long time to heal and often recur. These wounds are becoming more frequent due to population aging and increasing comorbidities [ 1 , 2 ]. The management of chronic wounds poses an …
Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

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An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

Clinical value of neuroimaging indicators of intracranial hypertension in patients with cerebral venous thrombosis

Open Access Intracranial Hypertension Diagnostic Neuroradiology

Intracranial hypertension (IH) frequently complicates cerebral venous thrombosis (CVT). It occurrs early in around 40% [ 1 – 3 ] and as a long-term complication in about 10% of patients [ 4 ]. IH is associated with visual loss [ 5 ], long-term …

Skin Grafting for Dermatologists: Past, Present, and Future

Open Access Skin Graft REVIEW

Skin grafting is a surgical technique used to replace damaged or missing skin with healthy skin. This procedure is commonly used in various medical fields, including dermatology, plastic surgery, and burn care. The primary objective of skin …

A Rare Case of Lemierre’s Syndrome due to Veillonella Parvula: A Dangerous and Forgotten Complication of a Septic Condition

Open Access Thrombophlebitis Clinical Report

This clinical case presents an unusual case of Lemierre’s syndrome (LS) in a young woman of 38-year-old. She arrived in the Emergency Department with a high fever and pharyngology resistant to antibiotic therapy with clarithromycin, ceftriaxone …

Platelet-rich plasma therapy for chronic cutaneous wounds stratified by etiology: a systematic review of randomized clinical trials

Open Access Venous Leg Ulcer Systematic Review

Chronic wounds are cutaneous wounds that do not heal or require a long time to heal and often recur. These wounds are becoming more frequent due to population aging and increasing comorbidities [ 1 , 2 ]. The management of chronic wounds poses an …

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