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Venous Leg Ulcer 

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  1. Open Access 01-12-2024 | OriginalPaper

    Associations between self-care advice and healing time in patients with venous leg ulcer– a Swedish registry-based study

    Venous leg ulcers (VLUs) affect mainly older adults, incidence and prevalence seem to increase [ 1 ], which can be assumed to be associated with an increased number of older people. A recent study points out that there is inaccuracy in the …

  2. Open Access 01-12-2023 | Venous Leg Ulcer | OriginalPaper

    Compression therapies for the treatment of venous leg ulcers: study protocol for a process evaluation in a randomised controlled trial, VenUS 6

    Venous leg ulcers (VLU) are common, recurring open wounds on the lower leg, caused by impaired blood flow in diseased or damaged leg veins. Sluggish blood flow increases venous pressure, which can severely impair wound healing [ 1 ]. VLUs are a …

  3. Open Access 01-12-2023 | Pentoxifylline | OriginalPaper

    Efficacy and safety of pentoxifylline for chronic venous leg ulcers: study protocol for a multicenter randomized controlled trial in China (ESPECT study)

    Chronic venous disease (CVD) is a common pathology of the circulation system and is characterized by symptoms and signs as a result of structural or functional abnormalities of the veins. The most common symptoms and signs include pain, tightness …

  4. Open Access 01-12-2023 | Leg Ulcer | OriginalPaper

    A randomised controlled trial of compression therapies for the treatment of venous leg ulcers (VenUS 6): study protocol for a pragmatic, multicentre, parallel-group, three-arm randomised controlled trial

    Note: the numbers in curly brackets in this protocol refer to SPIRIT checklist item numbers. The order of the items has been modified to group similar items (see …

  5. 01-12-2022 | Leg Ulcer

    Primary care disease management for venous leg ulceration—study protocol for the Ulcus Cruris Care [UCC] randomized controlled trial (DRKS00026126)

    Venous leg ulcers (VLUs) have a prevalence of 1–2% of the population in developed countries and account for up to 70% of chronic leg ulcerations [ 1 , 2 ]. Even with the best treatment, wound healing may take several months, and affected patients …

  6. Open Access 01-12-2022 | Leg Ulcer | OriginalPaper

    Exploring healthcare provider and patient perspectives on current outpatient care of venous leg ulcers and potential interventions to improve their treatment: a mixed methods study in the ulcus cruris care project

    In developed countries, venous leg ulcers (VLUs) have a prevalence of 1–2% of the population and account for approximately 70% of chronic leg ulcerations [ 1 , 2 ]. Due to rising age and comorbidity a steadily growing prevalence can be expected [ 3 …]. With an estimated mean prevalence of up to 0.64, approximately up to 1.8 million people in Germany are affected [

  7. Open Access 01-12-2021 | Leg Ulcer | OriginalPaper

    Prevalence and incidence of venous leg ulcers—a protocol for a systematic review

    Venous leg ulcers (VLUs) are open lesions of the lower limb and represent between 60 and 80% of all leg ulcerations that occur in the presence of venous disease [ 1 , 2 ]. Healing rates are protracted with only 60% on average healed by 12 weeks …

  8. 01-12-2020 | Leg Ulcer | ReviewPaper

    Venous Procedures to Treat Venous Leg Ulcers

    Venous leg ulcers (VLUs) affect millions of Americans and cost the US healthcare system an estimated 11.6 billion dollars a year [ 1 – 3 ]. Quality of life is also negatively impacted as patients with VLUs often have exudate, odor, and difficulty …

  9. Open Access 01-12-2021 | Leg Ulcer | OriginalPaper

    An observational study protocol to explore loneliness and systemic inflammation in an older adult population with chronic venous leg ulcers

    It is well established that individuals with chronic wounds, particularly those with chronic venous leg ulcers (CVLUs), have substantially reduced quality of life [ 1 – 3 ]. A wound is defined as chronic when it fails to reduce in size by 50% for …

  10. Open Access 01-06-2020 | Leg Ulcer | ReviewPaper

    A Systematic Review of Model-Based Economic Evaluations of Treatments for Venous Leg Ulcers

    Venous leg ulcers (VLU) are long-lasting wounds of the lower leg. They are usually formed after an injury, with slow healing due to increased blood pressure in the leg veins [ 1 ]. Typically, ulcers take 3–4 months to heal with appropriate …

  11. Open Access 01-02-2020 | Leg Ulcer | ReviewPaper

    The Most Severe Stage of Chronic Venous Disease: An Update on the Management of Patients with Venous Leg Ulcers

    Venous leg ulcers (VLUs) are the most severe manifestation of chronic venous disease (CVD). Due to their chronic nature, high recurrence rate and slow healing time, VLUs account for 80% of all leg ulcers seen in patients with CVD. VLUs impose a …

  12. 01-12-2020 | Leg Ulcer

    Impact of omega-3 fatty acid oral therapy on healing of chronic venous leg ulcers in older adults: Study protocol for a randomized controlled single-center trial

    Chronic venous leg ulcers (CVLUs) are open skin lesions of the lower legs arising in areas affected by venous hypertension that have been present for at least 6 weeks [ 1 ]. These common conditions affect 1% of the adult population and 3.6% of …

  13. Open Access 01-12-2019 | Leg Ulcer | OriginalPaper

    Aspirin versus placebo for the treatment of venous leg ulcers—a phase II, pilot, randomised trial (AVURT)

    Chronic venous leg ulcers (VLUs) are open wounds which can be large and frequently become infected and leak exudates, leading to significant pain and reduction in quality of life [ 1 , 2 ]. They are the result of an impaired venous return related …

  14. Open Access 01-12-2019 | Leg Ulcer | OriginalPaper

    A targeted interprofessional educational intervention to address therapeutic adherence of venous leg ulcer persons (TIEIVLU): study protocol for a randomized controlled trial

    Venous leg ulcers (VLU) are poorly healing wounds caused by chronic venous insufficiency (CVI) [ 1 ]. CVI is a form of peripheral vascular disease that originates from an obstruction of the venous system or a defective venous valve, leading to …

  15. 01-07-2019 | Leg Ulcer | OriginalPaper

    Comparison of EQ-5D-5L and SPVU-5D for measuring quality of life in patients with venous leg ulcers in an Australian setting

    Venous leg ulcers (VLUs) are wounds that occur on the legs due to venous diseases [ 1 ]. The estimated prevalence of leg ulcers is between 0.11 and 1.1% of the general population [ 2 – 6 ] and 52–80% of leg ulcers are caused by venous diseases [ 7 …

  16. 01-09-2016 | OriginalPaper

    Treat infected venous leg ulcers with appropriate culture-based antimicrobials and usual wound care

    Venous leg ulcers (VLUs) are the most common cause of chronic leg wounds and a common problem in the elderly population. As chronic open wounds, VLUs are susceptible to microbial invasion. While treatment guidelines agree that cultures and …

  17. Open Access 01-12-2018 | OriginalPaper

    Cost-effectiveness analysis of guideline-based optimal care for venous leg ulcers in Australia

    The prevalence of venous leg ulcers (VLUs) increases with age and although there are no recent or nationwide studies in Australia, prevalence is estimated at 0.33% in people aged over 60 years based on a study in Western Australia from the early …

  18. Open Access 01-12-2016 | OriginalPaper

    Aspirin in venous leg ulcer study (ASPiVLU): study protocol for a randomised controlled trial

    Venous leg ulcers (VLUs) are a common and costly problem, usually managed in general practice and community settings with variability in clinical practice [ 1 ]. Age-related venous leg ulceration is the most common cause of lower limb ulceration in …

  19. 01-10-2016 | OriginalPaper

    Critical Evaluation of Delayed Healing of Venous Leg Ulcers: A Retrospective Analysis in Canadian Patients

    Venous leg ulcers (VLUs) are the most common lower-extremity ulcers and have a challenging and recurrent course, which significantly impacts patient quality of life [ 1 – 4 ]. They are associated with prolonged disability, a negative socioeconomic …

  20. 01-12-2015 | OriginalPaper

    Use of Amnion Transfer in Resistant Nonhealing Venous Leg Ulcers

    In the treatment of venous leg ulcers, after adopting many treatment modalities, at times we are still left with a local indolent problem, “the resistant nonhealing venous ulcer.” With repeated surgical procedures failing to obtain a healed ulcer

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