A man receiving abiraterone for prostate cancer developed severe hypokalemia, which led to polymorphic ventricular tachycardia and cardiac arrest. It is important to consider iatrogenic causes in cases of arrhythmia.
Delve into the efficacy and safety data for the antibody–drug conjugates currently approved by the US FDA across tumor types such as hematologic, genitourinary, and gynecologic cancers.
Retroperitoneal lymph node dissection is a valuable tool in the management of testicular cancer. Gain an understanding of its key role in diagnosis and staging, and beyond.
Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.
The adoption of multiparametric MRI (mpMRI) and the Prostate Imaging Reporting and Data System has significantly changed prostate cancer diagnosis and management. These advancements, alongside novel biomarkers and updated International Society of …
Active surveillance (AS) is a strategy recommended by the European Association of Urology (EAU) for patients presenting with low or favourable intermediate-risk prostate cancer (PCa) [ 1 ]. AS involves identifying optimal timings for curative …
With the age of monoclonal antibodies (mabs) ushered in by Köhler and Milstein’s 1975 breakthrough in hybridoma technology, there came potential for developing specific, targeted cancer therapeutics. One of the most significant has been …
The global incidence of cancer is on the increase. It is expected that cancer will become the most frequent cause of death in most countries worldwide during the twenty-first century [ 1 , 2 ]. Despite advances in early detection and treatment …
An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.
A man receiving abiraterone for prostate cancer developed severe hypokalemia, which led to polymorphic ventricular tachycardia and cardiac arrest. It is important to consider iatrogenic causes in cases of arrhythmia.
Adjuvant pembrolizumab treatment after resection of lung metastases in a patient with renal cell carcinoma may have led to lung erosion that resulted in a pneumothorax.
The first reported case of PERM associated with anti-glycine receptor antibodies in a patient with bladder cancer. PERM, a stiff-person syndrome, has paraneoplastic etiology in about 20% of cases.
Open AccessRenal CancerKidneys, Ureters, Bladder, Retroperitoneum
Renal cancer is the third leading cause of genitourinary cancer death, and its incidence has been increasing over the past decade [ 1 ]. Renal cell carcinoma (RCC) constitutes approximately 70% of all renal cancers; its most common …
Some patients with metastatic prostate cancer carry a pathogenic germline variant (PV) in a gene, that is mainly associated with an increased risk of breast cancer in women. If they test positive for such a PV, prostate cancer patients are …
Renal cell carcinoma (RCC) represents one of the most prevalent urogenital malignancies with increasing incidence in developed countries [ 1 ]. Clear cell RCC is the predominant histological type, accounting for about 80% of all RCC cases.
The use of multiparametric magnetic resonance imaging (mpMRI) and targeted biopsies in patients with elevated prostate-specific antigen (PSA) lead to a significant improvement in the detection of early prostate cancer (PCa) as has been shown in …
