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11375 search results for:

Anti-CD25 Antibody 

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  1. Open Access 01-12-2024 | Arthritis | OriginalPaper

    Clinical and prognostic associations of anti-Jo-1 antibody levels in patients with antisynthetase syndrome

    Antisynthetase syndrome (ASS), a subtype of idiopathic inflammatory myopathies (IIM), manifests as one or more clinical symptoms such as interstitial lung disease (ILD), arthritis, mechanic’s hand, myositis, fever, Raynaud’s phenomenon, and the …

  2. Open Access 24-05-2024 | Positron Emission Tomography | Online First

    PET imaging of Aspergillus infection using Zirconium-89 labeled anti-β-glucan antibody fragments

    Invasive fungal infections (IFIs) are life-threatening diseases mainly seen in immunocompromised and immunodeficient patients [ 1 , 2 ]. Aspergillus fumigatus ( A. fumigatus ) is the most common IFI pathogen, affecting over 250,000 patients …

  3. 28-05-2024 | Diabetic Nephropathy | Online First

    Anti-GBM antibody in a patient with diabetic nephropathy; all that glitters is not gold

    We present the case of a 58-year-old male diabetic patient admitted to our department for a slight decrease in kidney function, with nephrotic range proteinuria, hematuria (16,000/ml) and positive anti-glomerular basement membrane antibodies.

  4. Open Access 01-12-2024 | OriginalPaper

    Single-domain antibody-based protein degrader for synucleinopathies

    Synucleinopathies are a group of neurodegenerative diseases characterized by the accumulation of α-synuclein (α-syn) in the brain, leading to motor and neuropsychiatric symptoms. Currently, there are no known cures for synucleinopathies, and …

  5. 21-05-2024 | Guillain-Barré Syndrome | Online First

    Anti-neurofascin-155 antibody mediated a distinct phenotype of chronic inflammatory demyelinating polyradiculoneuropathy

    Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) represents a clinically heterogeneous group of disabling disorders [ 1 ]. Autoantibodies targeting membrane proteins located at or near the node of Ranvier have been identified in …

  6. Open Access 29-05-2024 | Osteonecrosis | Online First

    Preventive Effects of Dental Pulp Stem Cell-conditioned Media on Anti-RANKL Antibody-Related Osteonecrosis of the Jaw

    Medication-related osteonecrosis of the jaw is a serious disease occurring in patients with cancer and osteoporosis, who are undergoing treatment with antiresorptive agents (ARAs) such as bisphosphonate (BP) or denosumab, an antibody targeting …

  7. 30-04-2024 | Pathology | ReviewPaper

    Antibody-Mediated Rejection: Mechanisms, Pathology, and Therapeutics

    Lung transplantation is the definitive treatment for patients with end-stage lung disease. With advances in surgical techniques, early survival after lung transplantation has improved in recent years. Unfortunately, long-term outcomes continue to …

  8. 28-05-2024 | Optic Neuritis | Online First

    MOG Antibody Disease: Nuances in Presentation, Diagnosis, and Management

    Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is an antibody-mediated inflammatory condition of the central nervous system (CNS) with overlapping clinical features which can mimic other neuroinflammatory conditions such as multiple …

  9. 01-05-2024 | Anti-CD3 Antibody | News

    Anti-CD3 monoclonal antibody/mipetresgene autoleucel/nivolumab

    Lack of efficacy
  10. Open Access 25-05-2024 | Fremanezumab | Online First

    Blood pressure monitoring in elderly migraineurs starting an anti-CGRP monoclonal antibody: a real-world prospective study

    Migraine is considered the second-highest cause of years lived with disability in the young-adult population [ 1 ]. While it is less prevalent among older individuals, the presence of comorbidities and the use of multiple medications can contribute …

  11. 01-05-2024 | Ovarian Cancer | EditorialNotes

    Antibody–drug conjugates (ADC special)—part 1

    Approximation to the magic bullet
  12. Open Access 25-04-2024 | Hemophagocytic Lymphohistiocytosis | Report

    Population Pharmacokinetics of the Anti-Interferon-Gamma Monoclonal Antibody Emapalumab: An Updated Analysis

    Hemophagocytic lymphohistiocytosis (HLH) is a rare, aggressive, and potentially fatal syndrome characterized by excessive, uncontrolled immune activation and systemic hyperinflammation [ 1 – 3 ]. Primary HLH is associated with genetic defects and …

  13. 20-05-2024 | Guillain-Barré Syndrome | Online First

    Clinical, paraclinical and outcome features of 166 patients with acute anti-GQ1b antibody syndrome

    Gangliosides, including GQ1b, are glycosphingolipids with a structure in which a hydrophobic ceramide and a hydrophilic sugar chain portion are bound, and sialic acid is bound to the sugar chain portion [ 1 , 2 ]. Gangliosides are abundant in the …

  14. Open Access 08-05-2024 | Brentuximab vedotin | ReviewPaper

    Antibody–drug conjugates in the treatment of lymphoid neoplasms

    Antibody-drug conjugates (ADCs) are a new class of monoclonal antibodies with the characteritic to specifically target tumor cells and to deliver a cytotoxic drug directly to the target cell thereby minimising side effects and improving the …

  15. Open Access 24-04-2024 | Type 1 Diabetes | Case Study

    Exogenous Insulin Antibody Syndrome (EIAS) Presenting in an Elderly, Long-Term Patient with Type 1 Diabetes Mellitus that Resolved with Low-Cost Outpatient Therapy with Mycophenolate Mofetil and Regular Insulin by Pump

    EIAS can cause hyperglycemia, hypoglycemia, and ketoacidosis in people with diabetes. This case in an older adult with type 1 diabetes shows how EIAS can be managed in an outpatient setting.

  16. 23-05-2024 | Myasthenia Gravis | Online First

    Diagnostic value of antibody concentration ratio for treatment-refractory myasthenia gravis

    Myasthenia gravis (MG) is an uncommon autoimmune disorder affecting the neuromuscular junction, manifested as fluctuating muscle weakness that can involve ocular, skeletal, or bulbar muscles. Its prevalence is estimated to be between 100–200 per …

  17. Open Access 01-12-2024 | Antiphospholipid Syndrome | OriginalPaper

    The clinical relevance of different antiphospholipid antibody profiles in pediatric rheumatology patients

    Antiphospholipid syndrome (APS) is a systemic autoimmune disorder occurring due to antibodies against phospholipid-binding plasma proteins (antiphospholipid antibodies [aPL]), mainly lupus anticoagulant test (LA), anticardiolipin antibodies (aCL) …

  18. 26-05-2024 | Hantavirus | Online First

    Single-Domain Antibody-Gold Nanoparticle Bioconjugates as Immunosensors for the Detection of Hantaviruses

    Heavy-chain antibodies are naturally produced by camelids and sharks [ 1 , 2 ]. Antigen binding occurs in the N-terminal domain of the antibody known as VHH (single variable domain on a heavy-chain antibody) or nanobody ® , registered trademark of …

  19. Open Access 01-12-2024 | Myopathy | OriginalPaper

    Atypical skin conditions of the neck and back as a dermal manifestation of anti-HMGCR antibody-positive myopathy

    Idiopathic inflammatory myopathies (IIMs) are a rare group of autoimmune diseases that can cause chronic inflammation of skeletal muscle and/or organs, including the skin, joints, lungs, gastrointestinal tract, and heart. Muscle involvement may …

  20. Open Access 01-12-2024 | Rabies | OriginalPaper

    One-dose intradermal rabies booster enhances rabies antibody production and avidity maturation

    The incidence of rabies in Thailand reached its peak in 2018 with 18 human deaths. Preexposure prophylaxis (PrEP) vaccination is thus recommended for high-risk populations. WHO has recently recommended that patients who are exposed to a suspected …

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