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Comparative Hepatology

Issue Special Issue 1/2004

11th International Symposium on the Cells of the Hepatic Sinusoid and their Relation to Other Cells

Content (58 Articles)

Open Access Preface

Preface

Robert S McCuskey

Open Access Proceedings

3-D structure of extracellular matrix regulates gene expression in cultured hepatic stellate cells to induce process elongation

Mitsuru Sato, Takeya Sato, Naosuke Kojima, Katsuyuki Imai, Nobuyo Higashi, Da-Ren Wang, Haruki Senoo

Open Access Proceedings

Signals for Hepatic Figrogenesis in Pediatric Cholestatic Liver Disease: Review and Hypothesis

Grant A Ramm, Anita C Hoskins, Sonia A Greco, Tamara N Pereira, Peter J Lewindon

Open Access Proceedings

Thioredoxin prevents thioacetamide-induced acute hepatitis

Hiroaki Okuyama, Yasuyuki Shimahara, Hajime Nakamura, Shinichi Araya, Norifumi Kawada, Yoshio Yamaoka, Junji Yodoi

Open Access Proceedings

PPAR Gamma and Hepatic Stellate Cells

Saswati Hazra, Takeo Miyahara, Richard A Rippe, Hidekazu Tsukamoto

Open Access Proceedings

N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1

Frank Murphy, Julian Waung, Jane Collins, Michael JP Arthur, Hideaki Nagase, Derek Mann, R Christopher Benyon, John P Iredale

Open Access Proceedings

Amino acids, L-Cysteine and L-Methionine, Attenuate Activation of Rat Stellate Cells in Primary Culture

Hiroko Matsui, Tokuko Takashima, Naoto Maeda, Yukihiro Imanishi, Naoki Uyama, Hiroaki Okuyama, Norifumi Kawada

Open Access Proceedings

Involvement of Galectin-1 and Galectin-3 in Proliferation and Migration of Rat Hepatic Stellate Cells in Culture

Naoto Maeda, Norifumi Kawada, Shuichi Seki, Kazuo Ikeda, Hiroaki Okuyama, Jun Hirabayashi, Ken-ichi Kasai, Katsutoshi Yoshizato

Open Access Proceedings

Suppression of Rat Stellate Cell Activation and Liver Fibrosis by a Japanese Herbal Medicine, Inchinko-to (TJ135)

Yukihiro Imanishi, Naoto Maeda, Hiroko Matsui, Tokuko Takashima, Shuichi Seki, Tetsuo Arakawa, Norifumi Kawada

Open Access Proceedings

Expression of leptin receptors in hepatic sinusoidal cells

Kenichi Ikejima, Tie Lang, Yan-Jun Zhang, Shunhei Yamashina, Hajime Honda, Mutsuko Yoshikawa, Miyoko Hirose, Nobuyuki Enomoto, Tsuneo Kitamura, Yoshiyuki Takei, Nobuhiro Sato

Open Access Proceedings

Intercellular Adhesive Structures Between Stellate Cells – An Analysis in Cultured Human Hepatic Stellate Cells

Katsuyuki Imai, Mitsuru Sato, Takeya Sato, Naosuke Kojima, Mitsutaka Miura, Nobuyo Higashi, Da-Ren Wang, Shinsuke Suzuki, Haruki Senoo

Open Access Proceedings

Activation of Stellate Cells Before Induction of Hepatic Fibrosis – Precise Timing in Choline-deficient Diet-fed Rat Model

Kazuhiko Besshi, Mutsunori Fujiwara, Haruki Senoo, Yasufumi Kondou, Yoshitaka Ohsugi, Taiji Hayashi, Kozo Ishidate

Open Access Proceedings

Periportal Stellate Cells in Subjects with Chronic Hepatitis C with a Varied Serum Alanine Aminotransferase Level

Mutsunori Fujiwara, Kazuhiko Besshi, Tamiko Takemura, Yukiko Ito, Takeshi Tsujino, Michiko Yamagata, Nobuyuki Minagawa, Ryo Nakata, Michiyasu Yoshitsugu, Yoshihisa Kato, Masashi Ihori, Isao Okayasu, Haruki Senoo, Kenjiro Wake

Open Access Proceedings

Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox

Nobuyo Higashi, Katsuyuki Imai, Mitsuru Sato, Takeya Sato, Naosuke Kojima, Mitsutaka Miura, Heidi L Wold, Jan Øivind Moskaug, Trond Berg, Kaare R Norum, Norbert Roos, Kenjiro Wake, Rune Blomhoff, Haruki Senoo

Open Access Proceedings

Expression of the Peroxisome Proliferator-Activated Receptors (PPARs) in the Hepatic Stellate Cells

Takeya Sato, Mitsuru Sato, Mitsutaka Miura, Nobuyo Higashi, Da-Ren Wang, Shinsuke Suzuki, Katsuyuki Imai, Naosuke Kojima, Haruki Senoo

Open Access Proceedings

Decreased Capacity for Vitamin A Storage in Hepatic Stellate Cells for Arctic Animals

Haruki Senoo, Kenjiro Wake, Heidi L Wold, Nobuyo Higashi, Katsuyuki Imai, Jan Øivind Moskaug, Naosuke Kojima, Mitsutaka Miura, Takeya Sato, Mitsuru Sato, Norbert Roos, Trond Berg, Kaare R Norum, Rune Blomhoff

Open Access Proceedings

5-Lipoxygenase (5-LO) is Involved in Kupffer Cell Survival. Possible Role of 5-LO Products in the Pathogenesis of Liver Fibrosis

Esther Titos, Anna Planagumà, Marta Làpez-Parra, Neus Villamor, Rosa Miquel, Wladimiro Jimànez, Vicente Arroyo, Francisca Rivera, Joan Rodàs, Joan Clària

Open Access Proceedings

Regulation of matrix metallo-proteinase expression by extracellular matrix components in cultured hepatic stellate cells

Da-Ren Wang, Mitsuru Sato, Takeya Sato, Naosuke Kojima, Nobuyo Higashi, Haruki Senoo

Open Access Proceedings

HMG-COA reductase inhibitor modulates collagen GEL-contraction by hepatic myofibroblast-like stellate cell line: involvement of geranylgeranylated proteins

Mikio Yanase, Hitoshi Ikeda, Atsushi Matsui, Eisei Noiri, Tomoaki Tomiya, Masahiro Arai, Yukiko Inoue, Kazuaki Tejima, Kayo Nagashima, Takako Nishikawa, Satoshi Kimura, Kenji Fujiwara, Marcos Rojkind, Itsuro Ogata

Open Access Proceedings

Clearance function of scavenger endothelial cells

Børd Smedsrød

Open Access Proceedings

Fc Gamma Receptors in the Hepatic Sinusoid

Henrik Braathen, Seyed A Mousavi, Trond Berg, Rune Kjeken

Open Access Proceedings

The liver sinusoidal endothelial cell hyaluronan receptor and its homolog, stabilin-1 – Their roles (known and unknown) in endocytosis

Peter AG McCourt, Berit Hansen, Dmitri Svistuonov, Sophie Johansson, Paola Longati, Kai Schledzewski, Julia Kzhyshkowska, Sergij Goerdt, Staffan Johansson, B–rd Smedsr–d

Open Access Proceedings

Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells

Geoffrey M Thiele, Michael J Duryee, Monte S Willis, Michael F Sorrell, Thomas L Freeman, Dean J Tuma, Lynell W Klassen

Open Access Proceedings

Preliminary analysis of the sinusoidal endothelium and space of Disse in ageing Papio hamadrayas

Victoria C Cogger, Alessandra Warren, Robin Fraser, Meng Ngu, Allan J McLean, David G Le Couteur

Open Access Proceedings

The effect of cytochalasin B – Loaded liposomes on the ultrastructure of the liver sieve

Filip Braet, Katrien Vekemans, Henriette Morselt, Ronald De Zanger, Eddie Wisse, Gerrit Scherphof, Jan Kamps

Open Access Proceedings

Study of the reappearance of sieve plate-like pores in immortalized sinusoidal endothelial cells – Effect of actin inhibitor in mixed perfusion cultures

Masaya Saito, Tomokazu Matsuura, Takahiro Masaki, Haruka Maehashi, Filip Braet

Open Access Proceedings

Role of Hepatic Stellate Cells in the Early Phase of Liver Regeneration in Rat: Formation of Tight Adhesion to Parenchymal Cells

Ayako Mabuchi, Ian Mullaney, Philip Sheard, Paul Hessian, Arthur Zimmermann, Haruki Senoo, Antony M Wheatley

Open Access Proceedings

Imaging Liver Development/Remodeling in the See-Through Medaka Fish

David E Hinton, Yuko Wakamatsu, Kenjiro Ozato, Shosaku Kashiwada

Open Access Proceedings

Immunomodulatory Role of Kupffer Cell in Liver Allografts

Zhaoli Sun, Tatehiko Wada, Sumito Hoshino, Keiichiro Uchikura, Andrew S Klein

Open Access Proceedings

Effects of acetaminophen on hepatic microcirculation in mice

Yoshiya Ito, Nancy W Machen, Edward R Abril, Robert S McCuskey

Open Access Proceedings

Functional Differences between Periportal and Perivenous Kupffer Cells Isolated by Digitonin-Collagenase Perfusion

Igor Bykov, Petri Ylipaasto, Leena Eerola, Kai O Lindros

Open Access Proceedings

The regulatory role of prostaglandin E2in liver (patho) physiology is controlled at its site of synthesis and its action on the receptors

Peter Dieter, Roland Scheibe, Yefgeniya Bezugla, Egbert Matthé, Sandra Schuch, Lars Treffkorn, Brigitte Bernard, Sabine Kamionka, Angelika Kolada

Open Access Proceedings

Signaling role of iron in NF-kappa B activation in hepatic macrophages

Shigang Xiong, Hongyun She, Hidekazu Tsukamoto

Open Access Proceedings

Thalidomide Prevents Alcoholic Liver Injury in Rats Through Inhibition of Kupffer Cell Sensitization

Nobuyuki Enomoto, Yoshiyuki Takei, Miyoko Hirose, Kenichi Ikejima, Tsuneo Kitamura, Nobuhiro Sato

Open Access Proceedings

Ultrastructural characterization of the death process of hepatocytes in neonatal mouse liver

Kazunobu Sasaki, Yuji Sonoda, Ichiro Kumano, Masumi Suda

Open Access Proceedings

Use of Flow Cytometric Analysis to Examine the Uptake of Apoptotic Bodies by Healthy Hepatocytes

Carol A Casey, Cheryl R Baldwin, Jacy L Kubik, Agnes M Hindemith, Benita L McVicker

Open Access Proceedings

Chemiluminescence detection of reactive oxygen species in isolated Kupffer cells during phagocytosis of Treponema pallidum

Rita Aldini, Antonella Marangoni, Massimo Guardigli, Vittorio Sambri, Lorenzo Giacani, Marco Montagnani, Aldo Roda, Roberto Cevenini

Open Access Proceedings

Heme oxygenase-1 induction in hepatocytes and non-parenchymal cells protects against liver injury during endotoxemia

Robert B Dorman, Mary Lynn Bajt, Anwar Farhood, January Mayes, Hartmut Jaeschke

Open Access Proceedings

Beta2-glycoprotein I inhibition of mouse Kupffer cells respiratory burst depends on liver architecture

Ligia F Gomes, Paula R Knox, Karin A Simon-Giavarotti, Virginia BC Junqueira, Jorge Sans, Luis A Videla

Open Access Proceedings

Role of AIM in Corynebacterium-induced granuloma formation in mice

Kazuhisa Kuwata, Hisami Watanabe, Takashi Yamamoto, Toru Miyazaki, Makoto Naito

Open Access Proceedings

Kupffer and stellate cell proteoglycans mediate malaria sporozoite targeting to the liver

Gabriele Pradel, Shivani Garapaty, Ute Frevert

Open Access Proceedings

Chlorotyrosine protein adducts are reliable biomarkers of neutrophil-induced cytotoxicity in vivo

Jaspreet S Gujral, Jack A Hinson, Hartmut Jaeschke

Open Access Proceedings

Cytotoxic reactions of CC531s towards liver sinusoidal endothelial cells: a microscopical study

Katrien Vekemans, Maarten Timmers, David Vermijlen, Ronald De Zanger, Eddie Wisse, Filip Braet

Open Access Proceedings

Confocal laser scanning microscopic study of the killing of metastatic colon carcinoma cells by Kupffer cells in the early onset of hepatic metastasis

Maarten Timmers, Katrien Vekemans, David Vermijlen, Ronald De Zanger, Eddie Wisse, Filip Braet

Open Access Proceedings

Elevated levels of tissue inhibitor of metalloproteinases (TIMPS) in human hepatocellular carcinomas

Eiji Matsumoto, Harushige Nakatsukasa, Kazuhiro Nouso, Shin-ichiro Nakamura, Mayumi Suzuki, Yoshiyuki Kobayashi, Masayuki Uemura, Syuichiro Sato, Ei-ichiro Yumoto, Junko Yokoyama, Sou Tsuboi, Hironori Tanaka, Yoshiataka Takuma, Tatsuya Fujikawa, Yasushi Shiratori

Open Access Proceedings

Migration of liver sinusoidal leukocytes to the liver colon adenocarcinoma metastases

Sergiusz Durowicz, Barbara Lukomska, Joanna Dłułniewska, Dorota Laszuk, Waldemar L Olszewski

Open Access Proceedings

Reduction of liver metastases outgrowth by tumour antigen-pulsed dendritic cell vaccination

Anna K Mels, Ilvy Mayen, Marjolein van Egmond, Robert HJ Beelen, Sybren Meijer, Cornelia D Richters

Open Access Proceedings

Correlation Between in Vivo Accumulation and in VitroAdhesion of Liver associated Lymphocytes in and Around Liver Adenocarcinoma Metastases

Marek Stanczyk, Waldemar Olszewski, Sergiusz Durowicz, Marek Maruszyński

Open Access Proceedings

Histopathological characterization of hepatocellular carcinomas which are undetected by dynamic computed tomography

Takatsugu Yamamoto, Kazuhiro Hirohashi, Katsu Sakabe, Taichi Shuto, Takahiro Uenishi, Masao Ogawa, Shogo Tanaka, Hiromu Tanaka, Shoji Kubo, Kenji Kaneda, Masami Sakurai

Open Access Proceedings

Expression of fibrillin-1 in focal nodular hyperplasia of the liver: a role in microcirculation adaptability

Sébastien Lepreux, Alexis Desmouliere, Jean Rosenbaum, Charles Balabaud, Paulette Bioulac-Sage

Open Access Proceedings

Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway

David Vermijlen, Dianzhong Luo, Christopher J Froelich, Jan P Medema, Jean A Kummer, Erik Willems, Filip Braet, Eddie Wisse

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.