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01-12-2021 | Osteoporosis | Original Article

Menarche age exceed 17 years and menopausal age smaller than 48 years may affect prevalence of osteoporosis for Chinese women

Authors: Yong He, Jin Huang, Guopeng Jiang, Huaming Wang, Jun Zhao, Zhilong Chen, Chen Zhang, Shihai Chen, Weiping Li, Dingpeng Li, Xingwen Xie

Published in: Archives of Osteoporosis | Issue 1/2021

Abstract

Summary

In this work, we used a cross-sectional study to evaluate influence of menarche age, menstrual cycle, menstrual period, menopausal age, and menopause years for osteoporosis in women from China. We found that different menarche age, menstrual cycle, menopausal years, and menopausal age are related with the prevalence of osteoporosis. However, menarche age exceeds 17 years and menopausal age smaller than 48 years are risk factors for osteoporosis in women.

Study design

A cross-sectional, population-based study.

Purpose

The purpose of this study was to explore relationship between prevalence of osteoporosis and menarche age, menstrual cycle, menstrual period, menopausal age, and menopause years for women.

Methods

From March to October 2016, the cluster sampling method was used to conduct an osteoporosis-related questionnaire survey on women aged 40–80 in two communities in Lanzhou City, Gansu, China, and bone mineral density(BMD)was carried out using the DTX-200 dual-energy X-ray absorptiometer produced by the US OSTEOMETER company. The relationship between prevalence of osteoporosis and menarche age, menstrual cycle, menstrual period, menopausal age, and menopause years were analyzed using logistic regression analysis.

Results

There were 2224 female participates enrolled in this study and average age was 61.60 ± 8.05 years and total rate of prevalence was 32.73%; among them, different menarche age, menstrual cycle, menopausal years, and menopausal age have statistical differences with the prevalence of osteoporosis, but there is no statistical difference between different menstruation and the prevalence of osteoporosis. Single logistic regression analysis found that older menarche age, earlier menopausal age, and longer menopausal years were related factors for the prevalence of osteoporosis, while menarche age exceed 17 years and menopausal age smaller than 48 years are risk factors for osteoporosis for women in multivariate regression analysis.

Conclusions

In China, ages at menarche and menopause are associated with prevalence of osteoporosis. Later, menarche and earlier menopause are associated with higher osteoporosis risk. Menarche and menopause history may help identify women with increased risk of developing osteoporosis.

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Title: Menarche age exceed 17 years and menopausal age smaller than 48 years may affect prevalence of osteoporosis for Chinese women
Authors: Yong He
Jin Huang
Guopeng Jiang
Huaming Wang
Jun Zhao
Zhilong Chen
Chen Zhang
Shihai Chen
Weiping Li
Dingpeng Li
Xingwen Xie
Publication date: 01-12-2021
Publisher: Springer London
Keywords: Osteoporosis
Osteoporosis
Estrogens
Published in: Archives of Osteoporosis / Issue 1/2021
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-021-00959-w

ACC 2024 Congress

Springer Medicine

Menarche age exceed 17 years and menopausal age smaller than 48 years may affect prevalence of osteoporosis for Chinese women

Abstract

Summary

Study design

Purpose

Methods

Results

Conclusions

ACC 2024 Congress

Springer Medicine

Abstract

Summary

Study design

Purpose

Methods

Results

Conclusions

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