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Osteoporosis International
Published in: Osteoporosis International 3/2003

01-03-2003 | Original Article

Risk factors for Colles' fracture in men and women: results from the European Prospective Osteoporosis Study

Author: A. J. Silman

Published in: Osteoporosis International | Issue 3/2003

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Abstract

The aim of this study was to determine the contribution of constitutional and lifestyle variables on the subsequent risk of distal forearm (Colles') fracture in a multinational, multicenter, population-prospective study. A total of 15,745 subjects from the European Vertebral Osteoporosis Study, who had completed a baseline questionnaire on lifestyle and constitutional factors, were followed up annually using a validated questionnaire to ascertain the occurrence of new fractures. Risks are expressed as hazard ratios (with 95% confidence intervals) derived from a Cox proportional hazards regression model. The incidence of Colles' fracture was 1.7 and 7.3 per 1000 person years in men and women, respectively. In women delayed menarche, over the age of 15 years, was associated with a modest increased risk [HR 1.5 (range 1.1–2.0)]. Regular walking in that group also increased the risk [HR 1.6 (1.2–2.2)] perhaps reflecting the increased exposure to risk of falling. None of the other factors examined revealed any important influences. The results are broadly in line with the few other published prospective studies suggesting only a modest role for these factors in influencing susceptibility to fracture.
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Metadata
Title
Risk factors for Colles' fracture in men and women: results from the European Prospective Osteoporosis Study
Author
A. J. Silman
Publication date
01-03-2003
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 3/2003
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-002-1364-1

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