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Osteoporosis International
Published in: Osteoporosis International 12/2006

01-12-2006 | Original Article

An estimate of the worldwide prevalence and disability associated with osteoporotic fractures

Authors: O. Johnell, J. A. Kanis

Published in: Osteoporosis International | Issue 12/2006

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Abstract

Objective

The aim of this study was to quantify the global burden of osteoporotic fracture worldwide.

Methods

The incidence of hip fractures was identified by systematic review and the incidence of osteoporotic fractures was imputed from the incidence of hip fractures in different regions of the world. Excess mortality and disability weights used age- and sex-specific data from Sweden to calculate the Disability Adjusted Life Years (DALYs) lost due to osteoporotic fracture.

Results

In the year 2000 there were an estimated 9.0 million osteoporotic fractures of which 1.6 million were at the hip, 1.7 million at the forearm and 1.4 million were clinical vertebral fractures. The greatest number of osteoporotic fractures occurred in Europe (34.8%). The total DALYs lost was 5.8 million of which 51% were accounted for by fractures that occurred in Europe and the Americas. World-wide, osteoporotic fractures accounted for 0.83% of the global burden of non-communicable disease and was 1.75% of the global burden in Europe. In Europe, osteoporotic fractures accounted for more DALYs lost than common cancers with the exception of lung cancer. For chronic musculo-skeletal disorders the DALYs lost in Europe due to osteoporosis (2.0 million) were less than for osteoarthrosis (3.1 million) but greater than for rheumatoid arthritis (1.0 million).

Conclusion

We conclude that osteoporotic fractures are a significant cause of morbidity and mortality, particularly in the developed countries.
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Metadata
Title
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
Authors
O. Johnell
J. A. Kanis
Publication date
01-12-2006
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 12/2006
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-006-0172-4

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