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Archives of Osteoporosis

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01-12-2021 | Osteoporosis | Original Article

New technology REMS for bone evaluation compared to DXA in adult women for the osteoporosis diagnosis: a real-life experience

Authors: Débora Meira Ramos Amorim, Eliane Naomi Sakane, Sergio Setsuo Maeda, Marise Lazaretti Castro

Published in: Archives of Osteoporosis | Issue 1/2021

Abstract

Summary

Osteoporosis is a prevalent skeletal disorder in postmenopausal women. REMS represents a potential technology for osteoporosis diagnosis in clinical practice.

Objective

To assess the accuracy of Radiofrequency Echographic Multi Spectrometry (REMS) technology in diagnosing osteoporosis in comparison with dual X-ray absorptiometry (DXA) on a population of Brazilian women.

Methods

A population of women age ranged between 30 and 80 was recruited at DXA Service of São Paulo School-Hospital, Brazil. They underwent REMS and DXA scans at the axial sites. The REMS accuracy for the osteoporosis diagnosis was evaluated in comparison with DXA on both sites. The intra-operator and inter-operator coefficient of variation (CV) was also calculated.

Results

A total of 343 patients were enrolled in the study. Erroneous scans due to poor quality acquisitions with both methods or to other technical reasons were excluded; 227 lumbar spine exams and 238 hip exams were acceptable for comparison analysis. The comparison between REMS and DXA outcomes showed that the average difference in BMD (expressed as bias±1.96 SD) was −0.026±0.179g/cm² for the spine and −0.027±0.156g/cm² for the femoral neck. When accepted 0.3 tolerance on T-score, there were no cases diagnosed as osteoporosis by DXA that were defined as normal by REMS. The REMS intra-operator CV was 0.51% for the lumbar spine and 1.08% for the femoral neck. The REMS inter-operator CV was 1.43% for the lumbar spine and 1.93% for the femoral neck.

Conclusion

The REMS approach had high accuracy for the diagnosis of osteoporosis in comparison with DXA in adult women. According to our results, this new technology has shown to be a promising alternative for populations without access to DXA densitometry.

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Title: New technology REMS for bone evaluation compared to DXA in adult women for the osteoporosis diagnosis: a real-life experience
Authors: Débora Meira Ramos Amorim
Eliane Naomi Sakane
Sergio Setsuo Maeda
Marise Lazaretti Castro
Publication date: 01-12-2021
Publisher: Springer London
Keywords: Osteoporosis
Osteoporosis
Published in: Archives of Osteoporosis / Issue 1/2021
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-021-00990-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

New technology REMS for bone evaluation compared to DXA in adult women for the osteoporosis diagnosis: a real-life experience

Abstract

Summary

Objective

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Summary

Objective

Methods

Results

Conclusion

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