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16167 search results for:

Estrogens 

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  1. Open Access 23-04-2024 | Exemestane | Online First

    Superior suppression of serum estrogens during neoadjuvant breast cancer treatment with letrozole compared to exemestane

    Antihormonal therapy is one of the mainstays in the treatment of estrogen receptor (ER) positive breast cancer, comprising 70–80% of all cases. During the last two decades, aromatase inhibitors (AIs) of the “third generation” pushed aside earlier …

  2. 01-07-2023 | Gynecomastia | News

    Conjugated-estrogens

    Hypercortisolaemia: case report
  3. 01-03-2023 | Estrogens | News

    Conjugated-estrogens

    Spontaneous coronary artery dissection: case report
  4. Open Access 12-07-2023 | Endometriosis | OriginalPaper

    Dienogest alone or dienogest combined with estrogens in the treatment of ovarian endometriomas, that is the question. A retrospective cohort study

    Endometriosis is a benign, chronic and inflammatory disease characterized by the presence of endometrium-like tissue outside the uterine cavity and is associated with pain and infertility [ 1 ]. The prevalence of the disease is estimated to be …

  5. Open Access 01-12-2023 | Breast Cancer | ReviewPaper

    Increasing incidence rate of breast cancer in cystic fibrosis - relationship between pathogenesis, oncogenesis and prediction of the treatment effect in the context of worse clinical outcome and prognosis of cystic fibrosis due to estrogens

    Cystic fibrosis (CF) is the most common genetic disease in the Caucasion population. Thanks to the CFTR modulators therapy, life expectancy will significantly improve. New therapeutic challenges can be expected, including diseases associated with …

  6. 29-09-2022 | Estrogens | OriginalPaper

    Pharmacokinetic Study of Conjugated Equine Estrogens in Healthy Chinese Postmenopausal Women Using a Parallel Two-Column LC–MS/MS Method

    When entering the fifth decade of life, most women begin to experience a series of menopausal-related symptoms that can last up to 10 years. Some of these can be fairly mild such as hot flashes, sweating, and irritability but some such as …

  7. 01-08-2021 | Meningioma | News

    Conjugated estrogens/cyproterone

    Multiple meningiomas: case report
  8. 01-02-2022 | Breast Cancer | OriginalPaper

    Associations of established breast cancer risk factors with urinary estrogens in postmenopausal women

    Epidemiologic studies have shown that elevated circulating endogenous estrogen levels, specifically the parent estrogens, estradiol and estrone, are associated with increased postmenopausal breast cancer (BCa) risk [ 1 – 4 ]. However, overall …

  9. 01-04-2021 | Nephroblastoma | News

    Conjugated estrogens/estradiol

    Pelvic seromucinous borderline tumour secondary to endometriotic cyst: case report
  10. 01-01-2021 | Systemic Lupus Erythematosus | News

    Estrogen/spironolactone

    Systemic lupus erythematosus and lupus nephritis: case report
  11. 01-11-2021 | Breast Cancer

    Investigating the role of endogenous estrogens, hormone replacement therapy, and blockade of estrogen receptor-α activity on breast metabolic signaling

    Breast cancer is the most common form of cancer in the USA. Among women, breast cancer accounts for 30% of all cancer diagnoses, with 281,550 new cases estimated in 2021 [ 1 ]. Factors related to estrogen production are linked to an increased …

  12. 01-06-2020 | Breast Cyst | News

    Conjugated estrogens

    Polypoid endometriosis: case report
  13. 01-03-2020 | Prolactinoma | News

    Conjugated-estrogens/estrogen/hormones

    Prolactinoma: case report
  14. 01-03-2020 | Sleep Apnea | ReviewPaper

    Beneficial effects of estrogens in obstructive sleep apnea hypopnea syndrome

    Epidemiological studies showing the higher frequency of obstructive sleep apnea hypopnea syndrome in men, polycystic ovary syndrome (PCOS), and in post-menopausal women suggest the beneficial role of estrogen. These findings are well supported by …

  15. Open Access 01-12-2020 | Dyspareunia | OriginalPaper

    Effects of vaginal administration of conjugated estrogens tablet on sexual function in postmenopausal women with sexual dysfunction: a double-blind, randomized, placebo-controlled trial

    Female sexual dysfunction (FSD) is an important condition which prevalence is difficult to estimate [ 1 ] and thought to be underreported. A 2005-report showed that 38 to 63% of women all over the world suffered from FSD [ 2 ]. The prevalence of …

  16. 01-11-2019 | Anthracycline | ReviewPaper

    Sex differences in anthracycline-induced cardiotoxicity: the benefits of estrogens

    Anthracyclines are the cornerstone for many oncologic treatments, but their cardiotoxicity has been recognized for several decades. Female subjects, especially before puberty and adolescence, or after menopause, seem to be more at increased risk …

  17. Open Access 01-12-2019 | Estrogens | ReviewPaper

    Structural plasticity of the hippocampus in response to estrogens in female rodents

    It is well established that estrogens affect neuroplasticity in a number of brain regions. In particular, estrogens modulate and mediate spine and synapse formation as well as neurogenesis in the hippocampal formation. In this review, we discuss …

  18. 01-04-2020 | Breast Cancer | OriginalPaper

    A cumulative index of exposure to endogenous estrogens and breast cancer by molecular subtypes in northern Mexican women

    According to a molecular classification of breast cancer (BC), at least three subtypes have been described: tumors that express estrogen and/or progesterone hormone receptors (HR+) and/or the human epidermal growth factor receptor 2 (HER2+), or …

  19. Open Access 01-12-2019 | Breast Cancer | OriginalPaper

    Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells

    Significant progresses have been reached in the diagnosis and therapy of breast cancer, nevertheless this malignancy still represents the most common leading cause of cancer-related deaths among women worldwide [ 1 ]. One of the major challenges …

  20. 01-11-2019 | Ovarian Cancer | OriginalPaper

    Circulating estrogens and postmenopausal ovarian and endometrial cancer risk among current hormone users in the Women’s Health Initiative Observational Study

    It is well established that unopposed estrogen therapy (ET) increases endometrial cancer risk, leading to contraindication among women with an intact uterus. ET is also associated with increased risk of ovarian cancer among women with a …

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