Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.
Autoimmune encephalitis is increasingly recognized as a treatable type of encephalitis in children. Early immunotherapy improves motor outcomes, but less is known about long-term management and treatment for relapsing disease.
In the most common subtypes of autoimmune limbic encephalitis, existing biomarkers often display unspecific and subtle changes. But [18F]DPA-714-PET-MRI shows potential as a direct imaging marker of neuroinflammation.
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Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.
In the most common subtypes of autoimmune limbic encephalitis, existing biomarkers often display unspecific and subtle changes. But [18F]DPA-714-PET-MRI shows potential as a direct imaging marker of neuroinflammation.
Mpox infection can have a range of symptoms, including CNS complications such as seizures, confusion, and encephalitis. In this case, PCR of the CSF was negative for the virus, but intrathecal antibody production confirmed the diagnosis.
Anti-N-methyl-D-aspartate receptor (NMDAr) autoimmune encephalitis (AE) is one of the most common causes of noninfectious encephalitis during pregnancy [ 1 – 3 ]. It is characterized by an autoimmune response against the NR1 subunit of NMDAr, which …
Neurotropic viruses may cause meningitis, myelitis, encephalitis, or meningoencephalitis. These inflammatory conditions of the central nervous system (CNS) may have serious and devastating consequences if not treated adequately. In this review, we …
Metagenomic next-generation sequencing (mNGS) offers advantages over conventional methods, mainly when rare pathogens are involved or when patients are on antibiotics. This umbrella analysis indicates that mNGS is a promising technique for …
With the increase in the number of cases of autoimmune encephalitis (AE), the cerebrospinal fluid (CSF) of people living with HIV (PLWH) showing abnormal behavior, cognitive impairment or abnormal movements should be actively screened for the …
Neuroimaging plays an increasingly critical role in clinical practice. PET Pearls is an interactive activity designed to improve your confidence and accuracy when interpreting imaging for early signs of cognitive impairment.
STEM-PD, the first in-human safety trial of stem cell therapy for Parkinson’s disease, began this year and marks a huge step forward for this type of treatment.
We talk to Prof. Malin Parmar about why stem cell therapy is such a good option for patients with Parkinson’s disease and get an update on the current status of the trial.
Anti-N-methyl-D-aspartate receptor (NMDAr) autoimmune encephalitis (AE) is one of the most common causes of noninfectious encephalitis during pregnancy [ 1 – 3 ]. It is characterized by an autoimmune response against the NR1 subunit of NMDAr, which …
Cryptococcal meningitis (CM) is an infectious disease of the central nervous system (CNS) caused by the fungal pathogen Cryptococcus neoformans . The disease has a very high mortality rate of 83.30–90.00% [ 1 – 3 ]. C. neoformans first invades the …
Since the zoonotic potential of Borna disease virus 1 (BoDV-1) was proven in 2018 [ 1 , 2 ], approximately 50 human cases within endemic regions in southern and eastern Germany have been reported to German health authorities [ 3 ]. Infections lead …
The Jarisch-Herxheimer reaction (JHR) is a febrile transient inflammatory syndrome triggered hours after antibiotic treatment of spirochete infections, including syphilis [ 1 , 2 ]. Clinically, JHR is typically manifested as an abrupt onset of …
Autoimmune encephalitis is increasingly recognized as a treatable type of encephalitis in children. Early immunotherapy improves motor outcomes, but less is known about long-term management and treatment for relapsing disease.
