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Neurology Inflammatory Brain Disease

Inflammatory Brain Disease

Infective endocarditis with septic embolization in the brain

This patient presented with right thigh swelling, fever, new-onset left hemiplegia, and seizures 18 months after kidney transplant. Enterococcus faecalis infective endocarditis with metastatic brain abscesses was diagnosed.

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Editor's Choice

How do autoimmune neurological diseases affect sleep?

Discover how to assess patients’ sleep, characteristic sleep disturbances, and options for treatment in autoimmune neurological diseases involving antibodies against NMDAR, LGI1, CASPR2, DPPX, AMPAR, Ma2, Hu, IgLON5, and AQP4.

Thunderclap headache due to ADEM

Thunderclap headache as a first clinical manifestation of acute disseminated encephalomyelitis has not been described before, and significant intracranial hypertension in ADEM is rarely reported. This unusual case combines both.

Evolving disease: viral to autoimmune encephalitis to MS

This unique case tracks the evolution from infectious to autoimmune encephalitis to multiple sclerosis in one patient, providing novel insights into the pathophysiology of neuroimmunological disorders.

ICI-induced encephalitis in a patient with HCC

Only the third reported case of encephalitis in a patient receiving atezolizumab plus bevacizumab for advanced hepatocellular carcinoma. The neurological symptoms quickly improved once steroid pulse therapy was started.

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Keynote webinar | Spotlight on sleep in brain health

  • Webinar | 02-05-2024 | 17:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Renata Riha
Dr. Sven Rupprecht
Developed by: Springer Medicine
Watch now

Case Studies

Infective endocarditis with septic embolization in the brain

This patient presented with right thigh swelling, fever, new-onset left hemiplegia, and seizures 18 months after kidney transplant. Enterococcus faecalis infective endocarditis with metastatic brain abscesses was diagnosed.

Thunderclap headache due to ADEM

Thunderclap headache as a first clinical manifestation of acute disseminated encephalomyelitis has not been described before, and significant intracranial hypertension in ADEM is rarely reported. This unusual case combines both.

Evolving disease: viral to autoimmune encephalitis to MS

This unique case tracks the evolution from infectious to autoimmune encephalitis to multiple sclerosis in one patient, providing novel insights into the pathophysiology of neuroimmunological disorders.

Episode 4: Stem cell therapy for PD

A new era for managing Parkinson’s disease?

STEM-PD, the first in-human safety trial of stem cell therapy for Parkinson’s disease, began this year and marks a huge step forward for this type of treatment.

We talk to Prof. Malin Parmar about why stem cell therapy is such a good option for patients with Parkinson’s disease and get an update on the current status of the trial.

Dr. Malin Parmar
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Current Reviews

Central nervous system manifestations in rheumatic diseases

As the role of neurologists in managing patients with rheumatic diseases expands, collaboration between rheumatologists and neurologists becomes increasingly vital. This literature review provides an overview of the central nervous system (CNS) …

A child with recurrent headache, fever and diffuse meningeal enhancement on MRI

Juvenile neurolupus presents primarily with neuropsychiatric manifestations which may also be the initial presentation. Such primary neuropsychiatric SLE (NPSLE) events are a consequence either of microvasculopathy and thrombosis, or of …

Differentiating rhythmic high-amplitude delta with superimposed (poly) spikes from extreme delta brushes: limitations of standardized nomenclature and implications for patient management

Electroencephalogram (EEG) is a powerful tool that helps clinicians with the diagnosis of epilepsy and other neurological diseases [ 1 ]. The combination of distribution, reactivity, morphology, and amplitude of different brain waves in relation to …

Further Reading

Daily functioning and (health-related) quality of life of young adult survivors of childhood bacterial meningitis

To investigate daily functioning, health-related quality of life (HRQoL), and overall quality of life (QoL) in young adult survivors of childhood bacterial meningitis (BM) thereby shedding light on very long-term outcomes and contributing to …

Are white matter hyperintensities associated with neuroborreliosis? The answer is twofold

Lyme neuroborreliosis is a spirochetal tick-borne infection, which typically presents with painful radiculitis, meningitis and/or cranial neuropathy. However, the presentation can vary with a wide range of possible manifestations, such as …

Evaluation of different standard and modified two-tier testing strategies for the laboratory diagnosis of lyme borreliosis in a European setting

Lyme borreliosis (LB) is caused by infection with Ixodes -transmitted spirochetes of the Borrelia burgdorferi sensu lato (s.l.) complex, and is the most prevalent tick-borne disease in the Northern Hemisphere. In North America, B. burgdorferi sensu …

Autoimmune and infectious encephalitis: development of a discriminative tool for early diagnosis and initiation of therapy

Encephalitis refers to inflammation of the brain with typically autoimmunological or infectious—often viral—etiology. Both are highly dynamic entities due to the rapid discovery of novel autoantibodies over the past 2 decades and because of …

Related topics

How do autoimmune neurological diseases affect sleep?

Discover how to assess patients’ sleep, characteristic sleep disturbances, and options for treatment in autoimmune neurological diseases involving antibodies against NMDAR, LGI1, CASPR2, DPPX, AMPAR, Ma2, Hu, IgLON5, and AQP4.

Read more