Open Access
12-03-2024 | Autoimmune Encephalitis | Letter to the Editors
[18F]DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis
Authors:
Wolfgang Roll, Jan Bauer, Andre Dik, Christoph Mueller, Philipp Backhaus, Saskia Räuber, Bastian Zinnhardt, Marco Gallus, Catriona Wimberley, Peter Körtvelyessy, Philipp Schindler, Werner Stenzel, Christian E. Elger, Albert Becker, Jan Lewerenz, Heinz Wiendl, Sven G. Meuth, Michael Schäfers, Nico Melzer
Published in:
Journal of Neurology
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Excerpt
A major cause of mesial temporal lobe seizures and epilepsy, memory disturbance and psychiatric symptoms is autoimmune limbic encephalitis (ALE), mediated by adaptive and concomitant innate autoimmune inflammatory processes. Standard clinical workup comprises magnetic resonance imaging (MRI), electroencephalography (EEG), CSF analysis, and neuropsychological assessment [
1]. …