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Open Access 12-03-2024 | Autoimmune Encephalitis | Letter to the Editors

[18F]DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis

Authors: Wolfgang Roll, Jan Bauer, Andre Dik, Christoph Mueller, Philipp Backhaus, Saskia Räuber, Bastian Zinnhardt, Marco Gallus, Catriona Wimberley, Peter Körtvelyessy, Philipp Schindler, Werner Stenzel, Christian E. Elger, Albert Becker, Jan Lewerenz, Heinz Wiendl, Sven G. Meuth, Michael Schäfers, Nico Melzer

Published in: Journal of Neurology

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Excerpt

A major cause of mesial temporal lobe seizures and epilepsy, memory disturbance and psychiatric symptoms is autoimmune limbic encephalitis (ALE), mediated by adaptive and concomitant innate autoimmune inflammatory processes. Standard clinical workup comprises magnetic resonance imaging (MRI), electroencephalography (EEG), CSF analysis, and neuropsychological assessment [1]. …
Literature
Metadata
Title
[18F]DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis
Authors
Wolfgang Roll
Jan Bauer
Andre Dik
Christoph Mueller
Philipp Backhaus
Saskia Räuber
Bastian Zinnhardt
Marco Gallus
Catriona Wimberley
Peter Körtvelyessy
Philipp Schindler
Werner Stenzel
Christian E. Elger
Albert Becker
Jan Lewerenz
Heinz Wiendl
Sven G. Meuth
Michael Schäfers
Nico Melzer
Publication date
12-03-2024
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-024-12302-7