Langerhans cell histiocytosis rarely presents with gastrointestinal involvement, leading to potential misdiagnosis. These two cases outline the clinical presentations as well as the pathway for a definitive diagnosis.
Optimal early nutrition has a lifelong positive impact on child development. But specific intrauterine and perinatal factors, pathological conditions, and dietary restrictions can contribute to micronutrient deficiencies. Which children are at risk and need supplementation?
A closer look at the interplay between alcohol consumption patterns and cardiovascular events, as associated with body fat mass and distribution, and metabolic dysfunction-associated steatotic liver disease.
IBD rarely begins in infancy and is extremely rare under 1 year. These three cases illustrate the importance of considering IBD in infants presenting with diarrhea, hematochezia, failure to thrive, or poor feeding.
A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.
ABI triggers inflammatory mediators, and the systemic inflammatory environment makes extracranial organs vulnerable to enhanced inflammation from medical procedures and infection. ALI is then exacerbated by an altered gut–lung axis.
Pooled analysis suggests bariatric surgery improves glycemic control, reduces the need for medication, and increases rate of diabetes remission compared with medical or lifestyle management.
Kidney injury is a known side-effect of using adalimumab to treat inflammatory bowel diseases, but has rarely been seen in children. Timely withdrawal can significantly reduce kidney damage but it is irreversible in some cases.
CENTERS study shows that magnetically guided capsule endoscopy with a detachable string is accurate and safe for detecting and grading esophagogastric varices in patients with cirrhosis.
Sciatica due to Streptococcus gallolyticus infection of the spinal epidural space led to a diagnosis of colorectal cancer in a person with none of the usual signs and symptoms.
Detecting sarcopenia in patients undergoing bariatric surgery can help maximize its effectiveness. But how is sarcopenia defined in this setting, and how should muscle mass, quality, and strength be measured?
Helicobacter pylori infection is associated with an increased risk for colorectal cancer incidence and mortality, but treatment for the infection can mitigate the risk.
Familiarize yourself with the epidemiology of MASLD, its association with cardiovascular disease, and how a holistic approach could tackle the rising incidences of both diseases.
Changing to a ciclosporin-based regimen resolved the signs and symptoms of hepatitis in a patient who presented with icterus, weakness, and lethargy two weeks after kidney transplantation and initiation of tacrolimus.
Systemic neoadjuvant therapy can improve disease-free survival and delay the development of metastases. What are the currently available options for locally advanced colon cancer?
All stages of metabolic dysfunction-associated steatotic liver disease (MASLD) are more common in people with type 2 diabetes than those without, but how feasible is universal screening of people with type 2 diabetes for liver fibrosis?
A comprehensive overview of mast cell activation syndrome, with a focus on the prominent gastrointestinal manifestations, some of which can mimic irritable bowel syndrome.
Pulmonary complications are common in patients with portal hypertension. Learn how to diagnose and treat the most common complications - hepatic hydrothorax, hepatopulmonary syndrome, and portopulmonary hypertension.
Daily resmetirom achieved significantly greater histologic improvement of both nonalcoholic steatohepatitis and liver fibrosis than placebo in the MAESTRO-NASH phase 3 trial.
