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Intensive Care Medicine
Published in: Intensive Care Medicine 4/2013

Open Access 01-04-2013 | Year in Review 2012

Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient–ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea

Authors: Massimo Antonelli, Marc Bonten, Maurizio Cecconi, Jean Chastre, Giuseppe Citerio, Giorgio Conti, J. R. Curtis, Goran Hedenstierna, Michael Joannidis, Duncan Macrae, Salvatore M. Maggiore, Jordi Mancebo, Alexandre Mebazaa, Jean-Charles Preiser, Patricia Rocco, Jean-François Timsit, Jan Wernerman, Haibo Zhang

Published in: Intensive Care Medicine | Issue 4/2013

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Excerpt

In 2012, the journal published several articles dealing with the use of noninvasive ventilation (NIV) in patients with acute respiratory failure (ARF). Carrillo et al. [1] prospectively evaluated the characteristics and outcomes of 184 patients with severe ARF due to community-acquired pneumonia treated with NIV, and determined the factors predicting NIV failure and mortality. NIV was successful in 63 % of patients. Confirming previous findings, the authors found that patients with “de novo” ARF failed NIV more frequently than those with previous cardiac or other respiratory disease (46 vs. 26 %). Worsening radiologic infiltrate 24 h after admission, maximum Sepsis-Related Organ Failure Assessment (SOFA) score, and higher heart rate and lower PaO2/FiO2 after 1 h of NIV were among the factors predicting NIV failure. NIV failure, maximum SOFA, and older age independently predicted hospital mortality. In patients with de novo ARF only, delayed intubation was consistently associated with a decreased survival. In 13 patients (six with chronic obstructive pulmonary disease), Piquilloud et al. [2] compared short-term patient–ventilator interaction during NIV with pressure support (PS) and neurally adjusted ventilatory assist (NAVA). As compared with PS, NAVA improved patient–ventilator synchrony during NIV by reducing trigger delay and severe asynchrony and by abolishing ineffective efforts and both delayed and premature cycling. Vaschetto et al. [3] performed a pilot study to assess the feasibility of using NIV to facilitate discontinuation of invasive mechanical ventilation in patients with resolving hypoxaemic ARF. Twenty patients randomly received immediate NIV after early extubation or conventional weaning. At the end of the study, arterial blood gas, success of extubation, septic complications, ICU length of stay, and mortality were similar, but the number of days without invasive ventilation at day 28 was higher in the NIV group than in the control group. The authors concluded that, in a highly experienced centre, early extubation followed by NIV is feasible and might facilitate liberation from mechanical ventilation in selected patients with hypoxaemic ARF. These findings were discussed in the editorial by Laghi and Fernandez [4]. …
Literature
1.
Carrillo A, Gonzalez-Diaz G, Ferrer M, Martinez-Quintana ME, Lopez-Martinez A, Llamas N, Alcazar M, Torres A (2012) Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure. Intensive Care Med 38:458–466PubMedCrossRef
2.
Piquilloud L, Tassaux D, Bialais E, Lambermont B, Sottiaux T, Roeseler J, Laterre PF, Jolliet P, Revelly JP (2012) Neurally adjusted ventilatory assist (NAVA) improves patient-ventilator interaction during non-invasive ventilation delivered by face mask. Intensive Care Med 38:1624–1631PubMedCrossRef
3.
Vaschetto R, Turucz E, Dellapiazza F, Guido S, Colombo D, Cammarota G, Della Corte F, Antonelli M, Navalesi P (2012) Noninvasive ventilation after early extubation in patients recovering from hypoxemic acute respiratory failure: a single-centre feasibility study. Intensive Care Med 38:1599–1606PubMedCrossRef
4.
Laghi F, Fernandez R (2012) Noninvasive ventilation for weaning in hypoxemic respiratory failure: not ready for prime time. Intensive Care Med 38:1583–1585PubMedCrossRef
5.
Ramirez A, Delord V, Khirani S, Leroux K, Cassier S, Kadlub N, Aubertin G, Picard A, Fauroux B (2012) Interfaces for long-term noninvasive positive pressure ventilation in children. Intensive Care Med 38:655–662PubMedCrossRef
6.
Olivieri C, Costa R, Conti G, Navalesi P (2012) Bench studies evaluating devices for non-invasive ventilation: critical analysis and future perspectives. Intensive Care Med 38:160–167PubMedCrossRef
7.
Ouanes-Besbes L, Dachraoui F, Ouanes I, Bouneb R, Jalloul F, Dlala M, Najjar MF, Abroug F (2012) NT-proBNP levels at spontaneous breathing trial help in the prediction of post-extubation respiratory distress. Intensive Care Med 38:788–795PubMedCrossRef
8.
Vivier E, Mekontso Dessap A, Dimassi S, Vargas F, Lyazidi A, Thille AW, Brochard L (2012) Diaphragm ultrasonography to estimate the work of breathing during non-invasive ventilation. Intensive Care Med 38:796–803PubMedCrossRef
9.
Banner MJ, Euliano NR, Martin AD, Al-Rawas N, Layon AJ, Gabrielli A (2012) Noninvasive work of breathing improves prediction of post-extubation outcome. Intensive Care Med 38:248–255PubMedCrossRef
10.
Blanch L, Sales B, Montanya J, Lucangelo U, Garcia-Esquirol O, Villagra A, Chacon E, Estruga A, Borelli M, Burgueno MJ, Oliva JC, Fernandez R, Villar J, Kacmarek R, Murias G (2012) Validation of the Better Care® system to detect ineffective efforts during expiration in mechanically ventilated patients: a pilot study. Intensive Care Med 38:772–780PubMedCrossRef
11.
Georgopoulos D (2012) Ineffective efforts during mechanical ventilation: the brain wants, the machine declines. Intensive Care Med 38:738–740PubMedCrossRef
12.
Arnal JM, Wysocki M, Novotni D, Demory D, Lopez R, Donati S, Granier I, Corno G, Durand-Gasselin J (2012) Safety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV®) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study. Intensive Care Med 38:781–787PubMedCrossRef
13.
14.
Leonhardt S, Lachmann B (2012) Electrical impedance tomography: the holy grail of ventilation and perfusion monitoring? Intensive Care Med 38:1917–1929PubMedCrossRef
15.
Patroniti N, Bellani G, Saccavino E, Zanella A, Grasselli G, Isgro S, Milan M, Foti G, Pesenti A (2012) Respiratory pattern during neurally adjusted ventilatory assist in acute respiratory failure patients. Intensive Care Med 38:230–239PubMedCrossRef
16.
de la Oliva P, Schuffelmann C, Gomez-Zamora A, Villar J, Kacmarek RM (2012) Asynchrony, neural drive, ventilatory variability and COMFORT: NAVA versus pressure support in pediatric patients. A non-randomized cross-over trial. Intensive Care Med 38:838–846PubMedCrossRef
17.
Fine-Goulden MR, Puppala NK, Durward A (2012) Mechanisms of ventilator dependence in children with neuromuscular and respiratory control disorders identified by monitoring diaphragm electrical activity. Intensive Care Med 38:2072–2079PubMedCrossRef
18.
Sinha P, Soni N (2012) Comparison of volumetric capnography and mixed expired gas methods to calculate physiological dead space in mechanically ventilated ICU patients. Intensive Care Med 38:1712–1717PubMedCrossRef
19.
Eastwood G, Bellomo R, Bailey M, Taori G, Pilcher D, Young P, Beasley R (2012) Arterial oxygen tension and mortality in mechanically ventilated patients. Intensive Care Med 38:91–98PubMedCrossRef
20.
Nesseler N, Frenel JV, Launey Y, Morcet J, Malledant Y, Seguin P (2012) Pulse oximetry and high-dose vasopressors: a comparison between forehead reflectance and finger transmission sensors. Intensive Care Med 38:1718–1722PubMedCrossRef
21.
Kondili E, Alexopoulou C, Xirouchaki N, Georgopoulos D (2012) Effects of propofol on sleep quality in mechanically ventilated critically ill patients: a physiological study. Intensive Care Med 38:1640–1646PubMedCrossRef
22.
Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A, Beale R, Brochard L, Brower R, Esteban A, Gattinoni L, Rhodes A, Slutsky AS, Vincent JL, Rubenfeld GD, Thompson BT, Ranieri VM (2012) The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med 38:1573–1582PubMedCrossRef
23.
Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS (2012) Acute respiratory distress syndrome: the Berlin definition. JAMA 307:2526–2533PubMed
24.
Gonzalez-Lopez A, Garcia-Prieto E, Batalla-Solis E, Amado-Rodriguez L, Avello N, Blanch L, Albaiceta GM (2012) Lung strain and biological response in mechanically ventilated patients. Intensive Care Med 38:240–247PubMedCrossRef
25.
Guo WA, Knight PR, Raghavendran K (2012) The receptor for advanced glycation end products and acute lung injury/acute respiratory distress syndrome. Intensive Care Med 38:1588–1598PubMedCrossRef
26.
Chiumello D, Taccone P, Berto V, Marino A, Migliara G, Lazzerini M, Gattinoni L (2012) Long-term outcomes in survivors of acute respiratory distress syndrome ventilated in supine or prone position. Intensive Care Med 38:221–229PubMedCrossRef
27.
Cox CE, Porter LS, Hough CL, White DB, Kahn JM, Carson SS, Tulsky JA, Keefe FJ (2012) Development and preliminary evaluation of a telephone-based coping skills training intervention for survivors of acute lung injury and their informal caregivers. Intensive Care Med 38:1289–1297PubMedCrossRef
28.
Grasso S, Terragni P, Birocco A, Urbino R, Del Sorbo L, Filippini C, Mascia L, Pesenti A, Zangrillo A, Gattinoni L, Ranieri VM (2012) ECMO criteria for influenza A (H1N1)-associated ARDS: role of transpulmonary pressure. Intensive Care Med 38:395–403PubMedCrossRef
29.
Richard JC, Marini JJ (2012) Transpulmonary pressure as a surrogate of plateau pressure for lung protective strategy: not perfect but more physiologic. Intensive Care Med 38:339–341PubMedCrossRef
30.
Korver EP, Ganushchak YM, Simons AP, Donker DW, Maessen JG, Weerwind PW (2012) Quantification of recirculation as an adjuvant to transthoracic echocardiography for optimization of dual-lumen extracorporeal life support. Intensive Care Med 38:906–909PubMedCrossRef
31.
MacLaren G, Combes A, Bartlett RH (2012) Contemporary extracorporeal membrane oxygenation for adult respiratory failure: life support in the new era. Intensive Care Med 38:210–220PubMedCrossRef
32.
Morris AH (2012) Exciting new ECMO technology awaits compelling scientific evidence for widespread use in adults with respiratory failure. Intensive Care Med 38:186–188PubMedCrossRef
33.
Kluge S, Braune SA, Engel M, Nierhaus A, Frings D, Ebelt H, Uhrig A, Metschke M, Wegscheider K, Suttorp N, Rousseau S (2012) Avoiding invasive mechanical ventilation by extracorporeal carbon dioxide removal in patients failing noninvasive ventilation. Intensive Care Med 38:1632–1639PubMedCrossRef
34.
Gottlieb J, Warnecke G, Hadem J, Dierich M, Wiesner O, Fuhner T, Strueber M, Haverich A, Welte T (2012) Outcome of critically ill lung transplant candidates on invasive respiratory support. Intensive Care Med 38:968–975PubMedCrossRef
35.
Oto J, Yamamoto K, Koike S, Onodera M, Imanaka H, Nishimura M (2012) Sleep quality of mechanically ventilated patients sedated with dexmedetomidine. Intensive Care Med 38:1982–1989PubMedCrossRef
36.
Burbano NH, Otero AV, Berry DE, Orr RA, Munoz RA (2012) Discontinuation of prolonged infusions of dexmedetomidine in critically ill children with heart disease. Intensive Care Med 38:300–307PubMedCrossRef
37.
Duman N, Tuzun F, Sutcuoglu S, Yesilirmak CD, Kumral A, Ozkan H (2012) Impact of volume guarantee on synchronized ventilation in preterm infants: a randomized controlled trial. Intensive Care Med 38:1358–1364PubMedCrossRef
38.
Bhatia R, Schmolzer GM, Davis PG, Tingay DG (2012) Electrical impedance tomography can rapidly detect small pneumothoraces in surfactant-depleted piglets. Intensive Care Med 38:308–315PubMedCrossRef
39.
Miedema M, de Jongh FH, Frerichs I, van Veenendaal MB, van Kaam AH (2012) Regional respiratory time constants during lung recruitment in high-frequency oscillatory ventilated preterm infants. Intensive Care Med 38:294–299PubMedCrossRef
40.
Marshall RP, Webb S, Bellingan GJ, Montgomery HE, Chaudhari B, McAnulty RJ, Humphries SE, Hill MR, Laurent GJ (2002) Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. Am J Respir Crit Care Med 166:646–650PubMedCrossRef
41.
Villar J, Flores C, Perez-Mendez L, Maca-Meyer N, Espinosa E, Blanco J, Sanguesa R, Muriel A, Tejera P, Muros M, Slutsky AS (2008) Angiotensin-converting enzyme insertion/deletion polymorphism is not associated with susceptibility and outcome in sepsis and acute respiratory distress syndrome. Intensive Care Med 34:488–495PubMedCrossRef
42.
Cruces P, Diaz F, Puga A, Erranz B, Donoso A, Carvajal C, Wilhelm J, Repetto GM (2012) Angiotensin-converting enzyme insertion/deletion polymorphism is associated with severe hypoxemia in pediatric ARDS. Intensive Care Med 38:113–119PubMedCrossRef
43.
da Silva PS, Fonseca MC, Iglesias SB, Junior EL, de Aguiar VE, de Carvalho WB (2012) Nebulized 0.5, 2.5 and 5 ml l-epinephrine for post-extubation stridor in children: a prospective, randomized, double-blind clinical trial. Intensive Care Med 38:286–293PubMedCrossRef
44.
Ganu SS, Gautam A, Wilkins B, Egan J (2012) Increase in use of non-invasive ventilation for infants with severe bronchiolitis is associated with decline in intubation rates over a decade. Intensive Care Med 38:1177–1183PubMedCrossRef
45.
Beasley JM, Jones SE (1981) Continuous positive airway pressure in bronchiolitis. Br Med J (Clin Res Ed) 283:1506–1508CrossRef
46.
Smalley N, MacLaren G, Best D, Paul E, Butt W (2012) Outcomes in children with refractory pneumonia supported with extracorporeal membrane oxygenation. Intensive Care Med 38:1001–1007PubMedCrossRef
47.
Paulides FM, Plotz FB, Verweij-van den Oudenrijn LP, van Gestel JP, Kampelmacher MJ (2012) Thirty years of home mechanical ventilation in children: escalating need for pediatric intensive care beds. Intensive Care Med 38:847–852PubMedCrossRef
48.
Todd Tzanetos DR, Yu C, Hernanz-Schulman M, Barr FE, Brown NJ (2012) Prospective study of the incidence and predictors of thrombus in children undergoing palliative surgery for single ventricle physiology. Intensive Care Med 38:105–112PubMedCrossRef
49.
Algra SO, Driessen MM, Schadenberg AW, Schouten AN, Haas F, Bollen CW, Houben ML, Jansen NJ (2012) Bedside prediction rule for infections after pediatric cardiac surgery. Intensive Care Med 38:474–481PubMedCrossRef
50.
Barker GM, O’Brien SM, Welke KF, Jacobs ML, Jacobs JP, Benjamin DK Jr, Peterson ED, Jaggers J, Li JS (2010) Major infection after pediatric cardiac surgery: a risk estimation model. Ann Thorac Surg 89:843–850PubMedCrossRef
51.
Wernovsky G, Wypij D, Jonas RA, Mayer JE Jr, Hanley FL, Hickey PR, Walsh AZ, Chang AC, Castaneda AR, Newburger JW et al (1995) Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants. A comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation 92:2226–2235PubMedCrossRef
52.
Gaies MG, Gurney JG, Yen AH, Napoli ML, Gajarski RJ, Ohye RG, Charpie JR, Hirsch JC (2010) Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass. Pediatr Crit Care Med 11:234–238PubMedCrossRef
53.
Davidson J, Tong S, Hancock H, Hauck A, da Cruz E, Kaufman J (2012) Prospective validation of the vasoactive-inotropic score and correlation to short-term outcomes in neonates and infants after cardiothoracic surgery. Intensive Care Med 38:1184–1190PubMedCrossRef
54.
Ricci Z, Garisto C, Favia I, Vitale V, Di Chiara L, Cogo PE (2012) Levosimendan infusion in newborns after corrective surgery for congenital heart disease: randomized controlled trial. Intensive Care Med 38:1198–1204PubMedCrossRef
55.
Hassinger AB, Wainwright MS, Lane JC, Haymond S, Backer CL, Wald E (2012) Elevated preoperative serum asymmetrical dimethylarginine (ADMA) is associated with poor outcomes after pediatric cardiac surgery. Intensive Care Med 38:1697–1704PubMedCrossRef
56.
Mastropietro CW, Mahan M, Valentine KM, Clark JA, Hines PC, Walters HL 3rd, Delius RE, Sarnaik AP, Rossi NF (2012) Copeptin as a marker of relative arginine vasopressin deficiency after pediatric cardiac surgery. Intensive Care Med 38:2047–2054PubMedCrossRef
57.
Chakkarapani E, Thoresen M, Liu X, Walloe L, Dingley J (2012) Xenon offers stable haemodynamics independent of induced hypothermia after hypoxia-ischaemia in newborn pigs. Intensive Care Med 38:316–323PubMedCrossRef
58.
Grollmuss O, Demontoux S, Capderou A, Serraf A, Belli E (2012) Electrical velocimetry as a tool for measuring cardiac output in small infants after heart surgery. Intensive Care Med 38:1032–1039PubMedCrossRef
59.
Konig K, Casalaz DM, Burke EJ, Watkins A (2012) Accuracy of non-invasive blood pressure monitoring in very preterm infants. Intensive Care Med 38:670–676PubMedCrossRef
60.
Nguah SB, Feldt T, Hoffmann S, Pelletier D, Ansong D, Sylverken J, Mehrfar P, Herr J, Thiel C, Ehrhardt S, Burchard GD, Cramer JP (2012) Cardiac function in Ghanaian children with severe malaria. Intensive Care Med 38:2032–2041PubMedCrossRef
61.
Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot–Olupot P, Akech SO, Nyeko R, Mtove G, Reyburn H, Lang T, Brent B, Evans JA, Tibenderana JK, Crawley J, Russell EC, Levin M, Babiker AG, Gibb DM (2011) Mortality after fluid bolus in African children with severe infection. N Engl J Med 364:2483–2495PubMedCrossRef
62.
Gill RS, Manouchehri N, Lee TF, Cho WJ, Thiesen A, Churchill T, Bigam DL, Cheung PY (2012) Cyclosporine treatment improves mesenteric perfusion and attenuates necrotizing enterocolitis (NEC)-like intestinal injury in asphyxiated newborn piglets during reoxygenation. Intensive Care Med 38:482–490PubMedCrossRef
63.
Stocker M, Allen M, Pool N, De Costa K, Combes J, West N, Burmester M (2012) Impact of an embedded simulation team training programme in a paediatric intensive care unit: a prospective, single-centre, longitudinal study. Intensive Care Med 38:99–104PubMedCrossRef
64.
Booth R, Sturgess E, Taberner-Stokes A, Peters M (2012) Zero tolerance prescribing: a strategy to reduce prescribing errors on the paediatric intensive care unit. Intensive Care Med 38:1858–1867PubMedCrossRef
65.
Martinez-Anton A, Sanchez JI, Casanueva L (2012) Impact of an intervention to reduce prescribing errors in a pediatric intensive care unit. Intensive Care Med 38:1532–1538PubMedCrossRef
66.
Imamura T, Nakagawa S, Goldman RD, Fujiwara T (2012) Validation of pediatric index of mortality 2 (PIM2) in a single pediatric intensive care unit in Japan. Intensive Care Med 38:649–654PubMedCrossRef
67.
Leteurtre S, Grandbastien B, Leclerc F, Parslow R (2012) International comparison of the performance of the paediatric index of mortality (PIM) 2 score in two national data sets. Intensive Care Med 38:1372–1380PubMedCrossRef
68.
Morris KP, McShane P, Stickley J, Parslow RC (2012) The relationship between blood lactate concentration, the Paediatric Index of Mortality 2 (PIM2) and mortality in paediatric intensive care. Intensive Care Med 38:2042–2046PubMedCrossRef
69.
Bastero-Minon P, Russell JL, Humpl T (2012) Frequency, characteristics, and outcomes of pediatric patients readmitted to the cardiac critical care unit. Intensive Care Med 38:1352–1357PubMedCrossRef
70.
Tibby SM, Durward A, Goh CT, Thorburn K, Morris K, Broadhead M, Peters MJ (2012) Clinical course and outcome for critically ill children with Down syndrome: a retrospective cohort study. Intensive Care Med 38:1365–1371PubMedCrossRef
71.
Colville G, Pierce C (2012) Patterns of post-traumatic stress symptoms in families after paediatric intensive care. Intensive Care Med 38:1523–1531PubMedCrossRef
72.
Shime N, Kawasaki T, Saito O, Akamine Y, Toda Y, Takeuchi M, Sugimura H, Sakurai Y, Iijima M, Ueta I, Shimizu N, Nakagawa S (2012) Incidence and risk factors for mortality in paediatric severe sepsis: results from the national paediatric intensive care registry in Japan. Intensive Care Med 38:1191–1197PubMedCrossRef
73.
Goldstein B, Giroir B, Randolph A (2005) International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 6:2–8PubMedCrossRef
74.
Gatterre P, Oualha M, Dupic L, Iserin F, Bodemer C, Lesage F, Hubert P (2012) Kawasaki disease: an unexpected etiology of shock and multiple organ dysfunction syndrome. Intensive Care Med 38:872–878PubMedCrossRef
75.
Paize F, Sarginson R, Makwana N, Baines PB, Thomson AP, Sinha I, Hart CA, Riordan A, Hawkins KC, Carrol ED, Parry CM (2012) Changes in the sublingual microcirculation and endothelial adhesion molecules during the course of severe meningococcal disease treated in the paediatric intensive care unit. Intensive Care Med 38:863–871PubMedCrossRef
76.
Jack T, Boehne M, Brent BE, Hoy L, Koditz H, Wessel A, Sasse M (2012) In-line filtration reduces severe complications and length of stay on pediatric intensive care unit: a prospective, randomized, controlled trial. Intensive Care Med 38:1008–1016PubMedCrossRef
77.
Lombel RM, Kommareddi M, Mottes T, Selewski DT, Han YY, Gipson DS, Collins KL, Heung M (2012) Implications of different fluid overload definitions in pediatric stem cell transplant patients requiring continuous renal replacement therapy. Intensive Care Med 38:663–669PubMedCrossRef
78.
Kirkham FJ, Wade AM, McElduff F, Boyd SG, Tasker RC, Edwards M, Neville BG, Peshu N, Newton CR (2012) Seizures in 204 comatose children: incidence and outcome. Intensive Care Med 38:853–862PubMedCrossRef
79.
Gunn JK, Beca J, Hunt RW, Olischar M, Shekerdemian LS (2012) Perioperative amplitude-integrated EEG and neurodevelopment in infants with congenital heart disease. Intensive Care Med 38:1539–1547PubMedCrossRef
80.
Welzing L, Oberthuer A, Junghaenel S, Harnischmacher U, Stutzer H, Roth B (2012) Remifentanil/midazolam versus fentanyl/midazolam for analgesia and sedation of mechanically ventilated neonates and young infants: a randomized controlled trial. Intensive Care Med 38:1017–1024PubMedCrossRef
81.
Silver G, Traube C, Kearney J, Kelly D, Yoon MJ, Nash Moyal W, Gangopadhyay M, Shao H, Ward MJ (2012) Detecting pediatric delirium: development of a rapid observational assessment tool. Intensive Care Med 38:1025–1031PubMedCrossRef
82.
Karaguzel G, Atay S, Deger O, Imamoglu M, Okten A (2012) The effects of three specific conditions related to critical care on adrenal function in children. Intensive Care Med 38:1689–1696PubMedCrossRef
83.
Menon K, Ward RE, Lawson ML, Gaboury I, Hutchison JS, Hebert PC (2010) A prospective multicenter study of adrenal function in critically ill children. Am J Respir Crit Care Med 182:246–251PubMedCrossRef
84.
Rippel C, South M, Butt WW, Shekerdemian LS (2012) Vitamin D status in critically ill children. Intensive Care Med 38:2055–2062PubMedCrossRef
85.
Plumb JO, Morris CG (2012) Clinical review: spinal imaging for the adult obtunded blunt trauma patient: update from 2004. Intensive Care Med 38:752–771PubMedCrossRef
86.
Zhang Z, Hongying N (2012) Efficacy and safety of regional citrate anticoagulation in critically ill patients undergoing continuous renal replacement therapy. Intensive Care Med 38:20–28PubMedCrossRef
87.
Brotschi B, Grass B, Weiss M, Doell C, Bernet V (2012) In-line filter included into the syringe infusion pump assembly reduces flow irregularities. Intensive Care Med 38:518–522PubMedCrossRef
88.
Mallat J, Barrailler S, Lemyze M, Benzidi Y, Pepy F, Gasan G, Tronchon L, Thevenin D (2012) The repeatability of Stewart’s parameters and anion gap in a cohort of critically ill adult patients. Intensive Care Med 38:2026–2031PubMedCrossRef
89.
Soh CR, Pietrobon R, Freiberger JJ, Chew ST, Rajgor D, Gandhi M, Shah J, Moon RE (2012) Hyperbaric oxygen therapy in necrotising soft tissue infections: a study of patients in the United States Nationwide Inpatient Sample. Intensive Care Med 38:1143–1151PubMedCrossRef
90.
Lefebvre JC, Lyazidi A, Parceiro M, Sferrazza Papa GF, Akoumianaki E, Pugin D, Tassaux D, Brochard L, Richard JC (2012) Bench testing of a new hyperbaric chamber ventilator at different atmospheric pressures. Intensive Care Med 38:1400–1404PubMedCrossRef
Metadata
Title
Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient–ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea
Authors
Massimo Antonelli
Marc Bonten
Maurizio Cecconi
Jean Chastre
Giuseppe Citerio
Giorgio Conti
J. R. Curtis
Goran Hedenstierna
Michael Joannidis
Duncan Macrae
Salvatore M. Maggiore
Jordi Mancebo
Alexandre Mebazaa
Jean-Charles Preiser
Patricia Rocco
Jean-François Timsit
Jan Wernerman
Haibo Zhang
Publication date
01-04-2013
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 4/2013
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-012-2807-6

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