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Testicular Tumor 

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  1. Open Access 27-01-2024 | Seminoma | OriginalPaper

    Predictive tissue markers in testicular germ cell tumors: Immunohistochemical expression of MLH1 and REV-7 proteins

    Although testicular cancer is rare in the general population, it represents the most frequent solid malignant tumor in young adult men [ 1 ]. Testicular Germ Cell Tumors (TGCTs) account for most cases of testicular cancer diagnoses [ 2 ]. TGCTs can …

  2. 21-02-2024 | Cytostatic Therapy | OriginalPaper

    Intratumoral Heterogeneity, Chemoresistance and Lymph Node Landing Zone Prognosis in Testicular Tumors Based on Histopathological Characteristics

  3. Open Access 01-12-2024 | OriginalPaper

    Myoid gonadal stromal tumor of the testis—the novel subtype of testicular gonadal stromal tumors: a case report and review of the literature

    Testicular tumor is a rare disease with no more than 4100 cases arising annually in Germany [ 1 ]. Histologically, around 90% of testicular neoplasms comprise of germ cell tumors (GCTs), while the remainder is composed of a variety of rare …

  4. Open Access 01-12-2024 | Seminoma | OriginalPaper

    Analysis of clinical characteristics, treatment patterns, and outcome of patients with bilateral testicular germ cell tumors

    Testicular cancer incidence is estimated at 1–1.5% among men in the Western world, and it is the most common malignancy in men aged 15–35 [ 1 ]. The major histological subtype of testicular cancer consists of germ cell tumors (GCT), 60% of which …

  5. 24-11-2023 | Metastasis | OriginalPaper

    Cytodiagnostic Dilemma in a Lung Mass as the First Presentation of Testicular Mixed Germ Cell Tumor Metastasis

    Testicular mixed germ cell tumors (TMGCTs) are rare malignant tumors comprising of two or more types of germ cell tumors. Their onset may be undetectable and the patient may first present with symptoms of metastasis. We hereby report a case of a …

  6. 13-02-2024 | Undescended Testis | Online First

    Risk for testicular germ cell tumors and spermatogenesis failure in post-pubertal undescended testes

    Testicular cancer accounts for approximately 1% of all cancers in males [ 1 ]. However, it is the most common cancer diagnosed in men aged 25–49 in the UK, accounting for around 14% of all cases in 2016–2018 [ 2 ]. Although survival rates are high …

  7. 24-01-2024 | Nonseminoma | OriginalPaper

    The prognostic impact of treatment centralization in patients with testicular germ cell tumors: analysis of hospital-based cancer registry data in Japan

    Testicular tumors are rare, numbering approximately 1% of all malignant tumors in males [ 1 ], and are the most frequent malignancy detected among males aged 15–44 years. Among testicular tumors, the most common histological subtype is the …

  8. 01-12-2023 | Ultrasound | OriginalPaper

    Multicenter retrospective study on benign testicular tumors in children: save as much as you can……please

    Testicular tumors (TT) are infrequent in the pediatric population under 15 years of age, representing 1% of all pediatric solid tumors [ 1 ]. Adults present a far higher incidence; therefore, the management of these tumors in children has been …

  9. 10-05-2023 | Magnetic Resonance Imaging | OriginalPaper

    Leydig cell tumor of the testis with characteristic contrast patterns of tumor and non-tumorous testicular parenchyma on MRI: a case report

    Testicular Leydig cell tumor (LCT) is a rare tumor that occurs in the interstitial tissue of the male testes, accounting for 1–3% of all testicular tumors [ 1 ]. LCTs are most frequently diagnosed in pre-pubertal boys aged 5–10 years and adult men …

  10. 28-08-2023 | Nonseminoma | OriginalPaper

    Differences in future life expectancy of testicular germ-cell tumor patients vs. age-matched male population-based controls

    Testicular germ-cell tumor (TGCT) is the most common solid malignancy among men aged 20–40 years, enclosing in it two distinct main histological entities: non-seminomas (NS-TGCT) and seminomas (S-TGCT) [ 1 , 2 ]. Its incidence has risen over the …

  11. 21-07-2023 | Testicular Tumor | OriginalPaper

    Malignant testicular tumors in children: overview on 10 years of Saudi Cancer Registry

    Neoplasms of the adnexa and testes are a rare type of tumors in the pediatric population, having an incidence of 0.05–2 per 100,000 children. These tumors have been described as quite rare in comparison to other neoplasms in the same age group [ 1 …

  12. Open Access 01-12-2022 | Computed Tomography | OriginalPaper

    Malignant testicular unclassified sex cord stromal tumor: a case report

    The World Health Organization (WHO) classification is widely used for pathological classification of testicular tumors [ 1 ], which are mainly divided into germ cell tumors and SCSTs. Most testicular tumors are germ cell tumors whereas SCSTs are …

  13. Open Access 27-06-2023 | Ultrasound | ReviewPaper

    Imaging Techniques to Differentiate Benign Testicular Masses from Germ Cell Tumors

    Testicular germ cell tumors (GCTs) are a rare malignancy with peak incidence in men aged 20 to 34 years [ 1 ]. Disease staging is critical in deciding treatment choice and sequence of treatments as more than 90% of testicular GCTs are considered …

  14. Open Access 04-03-2023 | Seminoma | OriginalPaper

    Testicular neoplasms: the interrelationships of serum levels of microRNA-371a-3p (M371) and classical tumor markers with histology, clinical staging, and age—a statistical analysis

    The factors histology, clinical stage (CS), serum tumor marker elevation, and patient age represent the traditional mainstay of clinical decision-making in testicular neoplasms according to recent guide-lines (Kliesch et al. 2021 ; Oldenburg et al.2022

  15. 01-04-2022 | Seminoma

    Emerging Role of Biomarkers in Testicular Germ Cell Tumors

    Testicular cancer is the most common solid tumor malignancy amongst young men aged 15–39 years [ 1 ]. In many ways, the modern management of testicular cancer is a true success story of oncology. The addition of cisplatin to chemotherapy regimens …

  16. 01-03-2022 | Cancer Biomarker

    Current Status of Stem Cell Transplant in Treatment of Testicular Germ Cell Tumors

    Testicular cancer is the most common malignancy in patients between the ages of 15 and 35 years old. Remarkable advancements in the treatment of testicular cancer over the past 60 years have led to a 5-year relative survival of 95% for all …

  17. Open Access 01-12-2023 | Ultrasound | OriginalPaper

    Brucella orchitis presenting as a testicular mass mimicking a testicular tumor: a rare case report

    Brucellosis is a zoonotic multiorgan infectious disease caused by Brucella species which are gram-negative coccobacilli [ 1 ]. Dogs, cattle, swine, sheep, goats, reindeer, and camels are the sources of infection. The transmission can occur through …

  18. 01-10-2021 | Seminoma | Letter

    Morphological and molecular heterogeneity in testicular germ cell tumors: implications for dedicated investigations

  19. Open Access 01-12-2021 | Seminoma | OriginalPaper

    Late testicular relapse two decades after primary extragonadal germ cell tumor with uncommon metastases: a case report

    The primary site of male germ cell tumors is most commonly the testicle. Extratesticular (extragonadal) onset of these tumors is reported in 3–7% of cases. It has been reported that metachronous testicular tumors may occur after the treatment of …

  20. 01-02-2022 | Cytostatic Therapy

    Preoperative clinical and radiographic predictors of major vascular surgery in patients with testicular cancer undergoing post-chemotherapy residual tumor resection (PC-RPLND)

    Post-chemotherapy lymph node dissection (PC-RPLND) after cisplatin-based chemotherapy for residual masses represents the therapeutic approach of choice in metastatic testicular cancer patients [ 1 ]. The goal of the surgical procedure is the …

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