Over the two last decades, bacterial multidrug resistance (MDR) has emerged and spread widely all around the world. The burden of this issue was estimated to be around five million deaths associated with bacterial resistance in 2019 [ 1 ]. The …

Over the past decades, the spread of carbapenemase-producing Enterobacterales (CPE) has become a worldwide public health threat [ 1 ]. The spread of carbapenemase-encoding genes is associated both to horizontal transmission of mobile genetic …

Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections are a common cause of hospital-acquired infections in endemic regions. Traditionally, polymyxins with or without other antibiotics are used for the treatment of CRKP infections, but their …

Antibiotic-resistant Acinetobacter baumannii (A. baumannii) is a common cause of hospital-acquired infections. This study aimed to identify independent factors associated with progression from nosocomial pneumonia to bacteremia in patients …

We tend to investigate the connection between time to appropriate therapy (TTAT) and prognosis in pediatric patients with nosocomial Klebsiella pneumoniae (K. pneumoniae) bloodstream infection, and find the optimal cutoff point for the empirical …

Over the last decade, nosocomial pneumonia caused by carbapenem-resistant organism (CRO) infection has become a significant important cause of mortality and morbidity worldwide, especially in critically ill patients [ 1 , 2 ]. Due to the broad …

Nosocomial pneumonia is one of the most common nosocomial infections, with an incidence of 6 to 38% in patients admitted to a level-1 trauma center [ 2 , 5 ]. In hospitalized trauma patients, nosocomial pneumonia is associated with poor prognoses …

Nosocomial pneumonia (NP) is the most commonly acquired infection in hospitals. In 2008, research on the incidence of NP in ten Asian countries, including China, Hong Kong, Malaysia, Pakistan, Philippines, Singapore, Korea, Taiwan, India, and …

Nosocomial pneumonia, including hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), are the leading causes of morbidity and mortality in the intensive care unit (ICU) [ 1 , 2 ]. Nosocomial pneumonia caused by …

Nosocomial pneumonia, comprising non-ventilated hospital-acquired, ventilated hospital-acquired, and ventilator-associated bacterial pneumonia (nvHABP/vHABP/VABP), is a relatively frequent infection in hospitalized patients, particularly those …

In accordance with the recommendations of, amongst others, the Surviving Sepsis Campaign and the recently published European treatment guidelines for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), in the event of a …

Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are the principal causes of infection among critically ill patients in intensive care units (ICU) [ 1 ]. Among all such cases of nosocomial pneumonia, Staphylococcus aureus … is the second most prevalent pathogen (17.8%), with 29.9% of the isolates in Europe being oxacillin-resistant [

This is the first article assessing the lung penetration of different doses of meropenem administered by continuous infusion in critically ill patients with nosocomial pneumonia. A dose increase leads to higher plasma and epithelial lining fluid …

This article is published with digital features to facilitate understanding of the article. To view the digital features for this article go to https://doi.org/10.6084/m9.figshare.12938396 .

Hospitalized patients with odontogenic infections (OIs) are at risk for life-threatening conditions and infection complications. These severe infections can lead to death despite accurate and multidisciplinary care [ 1 – 3 ]. Elderly patients [ 3 …4

Klebsiella pneumoniae is a threatening human pathogen that causes various diseases, including respiratory tract and urinary tract infections, blood infections, and liver abscesses [ 1 ]. Traditionally, bacterial infections have been classified into …

Critically ill patients often present with low serum iron levels or anemia. We evaluated the impact of iron levels and iron homeostasis on the efficacy and safety of cefiderocol, an iron-chelator siderophore cephalosporin, in patients with …