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Linear IgA Disease 

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  1. Open Access 01-12-2023 | Linear IgA Disease | OriginalPaper

    An unusual case of linear IgA disease affecting only the oral gingiva: a case report

    Desquamative gingivitis (DG) is a descriptive term used to indicate epithelial desquamation, erythema, erosion, and/or vesiculobullous lesions of the attached and marginal gingiva [ 1 ]. DG may be a manifestation of several mucocutaneous diseases …

  2. 01-03-2001 | OriginalPaper

    Mapping of epitopes on the BP180 ectodomain targeted by IgA and IgG autoantibodies in patients with the lamina lucida-type of linear IgA disease

  3. Open Access 01-12-2024 | Pulmonary Hemorrhage | OriginalPaper

    Atypical anti-glomerular basement membrane disease with membranous hyperplasia: diagnostic challenges and treatment variability

    This case report presents a detailed analysis of a 31-year-old male patient who presented with a complex array of clinical symptoms, including proteinuria, hematuria, edema, and kidney insufficiency. Despite undergoing multiple tests, the results …

  4. 22-05-2024 | Online First

    XIV National Congress SISMES

  5. Open Access 01-12-2024 | Biomarkers | OriginalPaper

    Deregulation in adult IgA vasculitis skin as the basis for the discovery of novel serum biomarkers

    Immunoglobulin A vasculitis (IgAV) is an immune complex leukocytoclastic vasculitis characterized by the dominant deposition of immunoglobulin (Ig) A in the affected vascular wall [ 1 ]. Cutaneous vasculitis in a form of palpable purpura represents …

  6. Open Access 07-05-2024 | Bronchial Asthma | Online First

    Airway and Systemic Immunoglobulin Profiling and Immune Response in Adult Asthma

    Asthma prevalence has seen a staggering rise with disease burden reaching epidemic proportions in the western world [ 1 , 2 ]. 3–10% of asthmatics have severe asthma where symptoms remain poorly controlled despite optimal treatment with inhaled …

  7. Open Access 01-12-2024 | Vaccination | OriginalPaper

    Correlates of protection and determinants of SARS-CoV-2 breakthrough infections 1 year after third dose vaccination

    Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has posed significant challenges to global health. Even though the pandemic is deemed to be under control, it continues to present significant challenges to public health, particularly for …

  8. Open Access 11-05-2024 | Acne | OriginalPaper

    Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris

    Acne vulgaris, an inflammatory skin disorder, poses a significant challenge in dermatology, affecting approximately 9% of the global population and up to 85% of adolescents [ 1 ]. Its pathogenesis is complex, involving genetic predisposition …

  9. 25-04-2024 | Diabetic Nephropathy | Online First

    Non-diabetic nephropathy in diabetic patients: incidence, HbA1c variability and other predictive factors, and implications

    Diabetes mellitus (DM) is a significant public health concern in both industrialized and developing nations. Based on data from 2019, it was reported that 9.3 percent of the population, or 463 million individuals, were diagnosed with diabetes [ 1 …

  10. 20-03-2024 | Events

    Abstracts

  11. 24-04-2024 | Abstract

    ECIO 2024 Book of Abstracts

  12. Open Access 26-04-2024 | Alport Syndrome | Online First

    X-linked Alport syndrome presenting in mother and son with the same unique histopathological features

    Alport syndrome has been linked to three different genes, that is, COL4A3, COL4A4 and COL4A5. It is characterized by progressive and non-specific glomerulosclerosis with irregular thickening of the glomerular basement membrane (GBM). At times, the …

  13. Open Access 01-08-2024 | Celiac Disease | OriginalPaper

    Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients

    Common variable immunodeficiency (CVID) is a rare disease, but still the most common symptomatic primary immunodeficiency in adults, with a prevalence of 1:25,000 to 1:50,000 in White people [ 1 ]. The immunodeficiency is characterized by a B-cell …

  14. 01-03-2024 | ReviewPaper

    The Complexity of Being A20: From Biological Functions to Genetic Associations

    A20, encoded by TNFAIP3, is a critical negative regulator of immune activation. A20 is a ubiquitin editing enzyme with multiple domains, each of which mediates or stabilizes a key ubiquitin modification. A20 targets diverse proteins that are …

  15. 09-05-2024 | Myasthenia Gravis | ReviewPaper

    FcRn Inhibitor Therapies in Neurologic Diseases

    In the last decade, the landscape of treating autoimmune diseases has evolved with the emergence and approval of novel targeted therapies. Several new biological agents offer selective and target-specific immunotherapy and therefore fewer side …

  16. Open Access 01-03-2024 | Abstract

    43rd International Symposium on Intensive Care & Emergency Medicine

  17. Open Access 01-12-2024 | Underweight | OriginalPaper

    Effect of preoperative immunonutrition on postoperative short-term clinical outcomes in patients with gastric cancer cachexia: a prospective randomized controlled trial

    Gastric cancer is the fifth most common cancer worldwide and the third leading cause of cancer deaths globally. In 2020, there were an estimated 1.09 million new cases of gastric cancer and 768,000 deaths globally, according to statistics. The …

  18. 25-03-2024 | Glomerulonephritis | Online First

    Lymphatic vessels in patients with crescentic glomerulonephritis: association with renal pathology and prognosis

    Crescentic glomerulonephritis is a severe form of glomerulonephritis, referred to as rapidly progressive glomerulonephritis. It is classified into three types based on the underlying mechanism and immunofluorescence patterns: anti-neutrophil …

  19. 16-01-2024 | Hematuria | OriginalPaper

    Childhood-onset IgA nephropathy: is long-term recovery possible?

    IgA nephropathy (IgAN), one of the leading causes chronic kidney disease stage 5 (CKD 5) in young adults [ 1 – 3 ], usually develops during late childhood–early adulthood [ 4 ]. Current data indicate that 10–30% of patients with IgAN reach CKD 5 …

  20. Open Access 01-12-2024 | Multiple Myeloma | OriginalPaper

    Evaluation of next-generation sequencing versus next-generation flow cytometry for minimal-residual-disease detection in Chinese patients with multiple myeloma

    Multiple myeloma (MM) is a clonal plasma-cell tumor, with high cytogenetic heterogeneity [ 1 ]. It is the second most common hematological malignancy in many countries [ 2 – 4 ] and has a substantial impact on public health. The specific incidence …

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