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115157 search results for:

Bone Tumor 

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  1. Open Access 12-04-2024 | Sarcoma | Letter

    Life Time Saga with Custom Mega Prosthesis in Bone Tumors (The Chennai Experience)

  2. Open Access 01-12-2024 | Osteosarcoma | OriginalPaper

    Patterns and treatment outcomes of primary bone tumors in children treated at tertiary referral hospital, Ethiopia

    Bone tumors arise from bone and closely related structures in the skeletal system [ 1 , 2 ]. Primary malignant bone tumors are more common in children and young adolescents than in the adult population, constitute approximately 6% of all cancers in …

  3. Open Access 01-12-2024 | Penile Cancer | OriginalPaper

    Bone in the penis” or fasciitis ossificans of the penis – a first time description of a pseudo-tumor at an extraordinary site

    Fasciitis ossificans is a pseudotumor of soft tissue, classified as a rare subtype of nodular fasciitis—a common reactive neoplasm of fibroblastic or myofibroblastic origin with an unknown etiology [ 1 ]. The presence of ossification in nodular …

  4. 12-01-2024 | Artificial Intelligence | ReviewPaper

    Diagnostic Performance of Artificial Intelligence in Detection of Primary Malignant Bone Tumors: a Meta-Analysis

    We aim to conduct a meta-analysis on studies that evaluated the diagnostic performance of artificial intelligence (AI) algorithms in the detection of primary bone tumors, distinguishing them from other bone lesions, and comparing them with …

  5. Open Access 01-12-2024 | giant cell tumor | OriginalPaper

    Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence

    Giant cell tumor of bone (GCTB) is a benign lesion which generally affects meta-epiphyseal region of long bones in adults aged from 20 to 40 years. Since it accounts for approximately 5% of all tumors primarily occurred in bone, [ 1 ] GCTB is not a …

  6. 28-12-2023 | giant cell tumor | OriginalPaper

    Recurrent Giant Cell Tumor of Sphenoid Bone: A Rare Finding

    Giant Cell Tumors of the skull are rare and mostly occur in the middle cranial fossa. Radiological investigations serve as adjunct modalities; however, histopathological confirmation is mandatory. Ten to forty% of GCTs may be recurrent. Complete …

  7. 10-03-2024 | Molecular Imaging | Online First

    Revolutionizing bone tumor management: cutting-edge breakthroughs in limb-saving treatments

    Limb salvage surgery has revolutionized the approach to bone tumors in orthopedic oncology, steering away from historical amputations toward preserving limb function and enhancing patient quality of life. This transformative shift underscores the …

  8. 27-02-2024 | Magnetic Resonance Imaging | Online First

    Bone tumors: state-of-the-art imaging

    Imaging plays a central role in the management of patients with bone tumors. A number of imaging modalities are available, with different techniques having unique applications that render their use advantageous for various clinical purposes.

  9. Open Access 08-04-2024 | Online First

    En-bloc spondylectomy in the lumbar spine: indications, results and complications in a series of 47 patients affected by primary malignant bone tumors

    Although the spine is the most frequent site for bone metastases, primary benign aggressive and malignant bone tumors are uncommon. Therapy is usually based on the combination of chemotherapy, radiotherapy and surgery, with different schedules …

  10. 21-03-2024 | Multiple Myeloma | Online First

    Desmoplastic small round cell tumor of bone revealed by 18F-FDG PET/CT: a case report with literature review

    A 50-year-old male presented with neck and shoulder pain. Chest CT and 18F-FDG PET/CT revealed osteolytic bone destruction in the left first rib and thoracic vertebrae with increased FDG uptake. Rib biopsy pathology indicated desmoplastic small …

  11. Open Access 01-03-2024 | Denosumab | OriginalPaper

    Treatment of bone metastases from solid tumors with bone-modifying agents: a web survey of Italian oncologists investigating patterns of practice drug prescription and prevention of side effects

    Bone is a frequent site of metastases in patients with solid tumors (breast, prostate, lung, renal, and other cancers) [ 1 ]. Bone-modifying agents (BMAs), also known as bone-targeted agents or antiresorptive drugs, include bisphosphonates and …

  12. Open Access 16-01-2024 | Sarcoma | ReviewPaper

    Current challenges and practical aspects of molecular pathology for bone and soft tissue tumors

    This review shows the extraordinary change molecular pathology has induced in the classification, diagnosis, and clinical practice of molecular pathologists dealing with sarcomas. We have primarily focused on the practical aspects of molecular …

  13. Open Access 01-12-2024 | Bone Metastasis | OriginalPaper

    IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis

    Nasopharyngeal carcinoma is a common malignancy originating from epithelial tissue with a distinct regional distribution, commonly found in certain regions of East and Southeast Asia, such as southern China [ 1 ]. Although early-stage …

  14. Open Access 01-03-2024 | Metastasis | OriginalPaper

    Development of a nomogram to predict the prognosis of patients with secondary bone tumors in the intensive care unit: a retrospective analysis based on the MIMIC IV database

    Bone is one of the most common sites of metastasis for malignant tumors, affecting many patients with advanced cancer (Coleman et al. 2020a ). Bone metastases often lead to skeletal morbidity called skeletal-related events (SREs) (Moos et al. 2019 …

  15. 29-02-2024 | giant cell tumor | Online First

    Giant Cell Tumor of the Temporal Bone with Direct Invasion into the Middle Ear and Skull Base: A Case Report

    Giant cell tumor (GCT) of bone is a rare, benign, osteolytic neoplasm that most commonly occurs in early adulthood and often involves the long bones of the body. Although GCT largely affects the epiphyses of long bones, several reports of GCT …

  16. 16-02-2024 | OriginalPaper

    Similar complications, implant survival, and function following modular prosthesis and allograft-prosthesis composite reconstructions of the proximal femur for primary bone tumors: a systematic review and meta-analysis

    The proximal femur is one of the most common locations for bone tumors [ 1 , 2 ]. The two main types of reconstruction of the proximal femur are modular prosthesis (MP) and allograft-prosthesis composite (APC) [ 3 – 6 ]. Both types of …

  17. 23-08-2023 | giant cell tumor | Report

    A Case of Fibrosarcoma Arising in Giant Cell Tumor of Bone: a Rare Entity

    Giant cell tumor of bone is a rare primary skeletal lesion accounting for approximately 5% of all primary bone tumors. Although classified as a primary benign bone tumor, a giant cell tumor of bone has a high recurrence rate reaching 65%, along …

  18. 08-11-2023 | Denosumab | OriginalPaper

    Effect of denosumab in treatment of unresectable spine and sacrum giant cell tumor of bone

    Giant cell tumor of bone (GCTB) is a rare tumor of the bone that is locally invasive. Surgery is the primary treatment that is usually done by intralesional curettage. In pelvis and spine surgery may be associated with high rate of complications …

  19. Open Access 17-01-2024 | Soft Tissue Tumor | Online First

    Recent advances in molecular profiling of bone and soft tissue tumors

    The molecular characterization of soft tissue and bone tumors is a rapidly evolving field that has changed the perspective of how these tumors are diagnosed today. Morphology and clinico-radiological context still represent the cornerstone of …

  20. 07-09-2023 | Parathyroidectomy | OriginalPaper

    Gene Polymorphism Influencing Persistent Bone Resorption in Brown Tumor: A Case Series with Possible Pathogenesis and Potential Therapeutic Approach

    Brown tumor represents a terminal stage of bone remodeling process due to an imbalance between osteoclastic and osteoblastic activity. It represents a reparative cellular process, rather than a neoplastic process mostly associated with primary or …

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