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giant cell tumor 

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  1. Open Access 01-12-2024 | giant cell tumor | OriginalPaper

    Giant cell tumor of soft tissue involving thyroid gland: a case report and review of the literature

    Giant cell tumor of soft tissue (GCT-ST) is a relatively rare hyperplastic neoplasm, with morphological characteristics similar to those arising from the bone [ 1 , 2 ]. Salm et al . first described the presence of GCT-ST in 1972, characterized by …

  2. 19-12-2023 | giant cell tumor | OriginalPaper

    Giant Cell Tumor of Mandible : A Case Report

    Giant cell tumor is locally aggressive primary benign neoplasm of bone with tendency of frequent recurrence, metastasis and malignant transformation. Because of the rarity of the disease involving mandible, no definite treatment guideline is …

  3. 28-12-2023 | giant cell tumor | OriginalPaper

    Recurrent Giant Cell Tumor of Sphenoid Bone: A Rare Finding

    Giant Cell Tumors of the skull are rare and mostly occur in the middle cranial fossa. Radiological investigations serve as adjunct modalities; however, histopathological confirmation is mandatory. Ten to forty% of GCTs may be recurrent. Complete …

  4. Open Access 01-12-2024 | giant cell tumor | OriginalPaper

    Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence

    Giant cell tumor of bone (GCTB) is a benign lesion which generally affects meta-epiphyseal region of long bones in adults aged from 20 to 40 years. Since it accounts for approximately 5% of all tumors primarily occurred in bone, [ 1 ] GCTB is not a …

  5. 14-03-2024 | giant cell tumor | Online First

    Giant Cell Tumor of the Mandible: A Case Report with an Argument on a Possible Diagnostic Tool

    Giant cell tumor (GCT) is a benign, locally aggressive neoplasm with a high recurrence rate with common occurrence in the long bone and the cases in the maxillofacial region bone are very rare. Due to the paucity of the cases, there is not enough …

  6. 29-02-2024 | giant cell tumor | Online First

    Giant Cell Tumor of the Temporal Bone with Direct Invasion into the Middle Ear and Skull Base: A Case Report

    Giant cell tumor (GCT) of bone is a rare, benign, osteolytic neoplasm that most commonly occurs in early adulthood and often involves the long bones of the body. Although GCT largely affects the epiphyses of long bones, several reports of GCT …

  7. Open Access 01-12-2024 | giant cell tumor | OriginalPaper

    Deep learning for differentiation of osteolytic osteosarcoma and giant cell tumor around the knee joint on radiographs: a multicenter study

    Bone tumors are a group of primary or secondary neoplastic lesions of bone with various pathological types and biological behaviors [ 1 ]. According to the 5th edition of the World Health Organization (WHO) classification of bone tumors published …

  8. 23-08-2023 | giant cell tumor | Report

    A Case of Fibrosarcoma Arising in Giant Cell Tumor of Bone: a Rare Entity

    Giant cell tumor of bone is a rare primary skeletal lesion accounting for approximately 5% of all primary bone tumors. Although classified as a primary benign bone tumor, a giant cell tumor of bone has a high recurrence rate reaching 65%, along …

  9. 08-11-2023 | Denosumab | OriginalPaper

    Effect of denosumab in treatment of unresectable spine and sacrum giant cell tumor of bone

    Giant cell tumor of bone (GCTB) is a rare tumor of the bone that is locally invasive. Surgery is the primary treatment that is usually done by intralesional curettage. In pelvis and spine surgery may be associated with high rate of complications …

  10. Open Access 01-12-2023 | giant cell tumor | OriginalPaper

    Complications and prognosis of primary thoracic and lumbar giant cell tumors treated by total tumor resection

    Giant cell tumor (GCT) is a primary bone tumor. This locally aggressive tumor is more commonly seen in the epiphysis of the long diaphysis and in the spine, accounting for approximately 5% of all primary bone tumors [ 1 ]. Spinal giant cell tumor

  11. Open Access 01-12-2023 | giant cell tumor | OriginalPaper

    Clinical retrospective analysis with a predictive model for diffused-tenosynovial giant cell tumors of the temporomandibular joint

    Tendon Sheath of Giant Cell Tumor (TSGCT), also known as Pigmented Villonodular Synovitis (PVNS), is an uncommon benign soft tissue tumor that can cause joint or limb swelling, discomfort, stiffness, and restricted mobility [ 1 ]. TSGCT is thought …

  12. 29-07-2023 | Denosumab | OriginalPaper

    Diagnosis and monitoring denosumab therapy of giant cell tumors of bone: radiologic-pathologic correlation

    Giant cell tumor of bone (GCTB) is characterized by neoplastic proliferating mononuclear stromal cells (NC) and osteoclast-like giant cells (GC). The NCs express receptor activator of nuclear factor kappa-B-ligand (RANKL), which binds to RANK on …

  13. Open Access 01-12-2023 | giant cell tumor | OriginalPaper

    Tenosynovial giant cell tumor: a case report

    As per the 2020 World Health Organization (WHO) classification, tenosynovial giant cell tumor (TGCT) encompasses a group of lesions most often arising from the synovium of joints, bursae, and tendon sheaths and showing synovial differentiation [ 1 …

  14. Open Access 01-12-2023 | giant cell tumor | OriginalPaper

    Partial sternectomy with reconstruction of a giant cell tumor of the sternum, a case report, Saudi, Arabia

    Giant cell tumor (GCT) is a relatively common benign bone tumor that can be locally aggressive, although it rarely affects the sternum. Primary sternal tumors are very rare, with secondary sternal tumors being more common [ 1 , 2 ]. GCT is a …

  15. 22-07-2023 | giant cell tumor | OriginalPaper

    Management of Giant Cell Tumor of the Hyoid bone- A rare Clinical Entity with Review of Literature

    Background: Giant cell tumors (GCTs) are typically found in the long bones but can also occur in the head and neck region. GCT of the larynx is a rare entity with only 42 reported cases in the international literature. Furthermore, to the best of …

  16. 27-04-2023 | giant cell tumor | ReviewPaper

    Denosumab for giant cell tumors of bone from 2010 to 2022: a bibliometric analysis

    Giant cell tumors of the bone (GCTB) are considered moderately malignant bone tumors. Denosumab, as a neoadjuvant therapy, provides new possibilities for treating GCTB. However, even after multiple studies and long-term clinical trials, there are …

  17. 16-05-2023 | Bisphosphonate | OriginalPaper

    An improved total en bloc spondylectomy for L5 vertebral giant cell tumor through a single-stage posterior approach

    Giant cell tumor (GCT) of the bone is a locally aggressive and rarely metastasizing tumor, accounting for about 22% of all benign bone tumors [ 1 , 2 ]. The incidence of GCT in spinal motion segments ranges from 1.4 to 9.4% [ 3 ], with a relatively …

  18. Open Access 01-12-2023 | giant cell tumor | OriginalPaper

    Giant cell tumors of the distal ulna: long-term recurrence rate and functional outcomes of en bloc resection versus curettage in a multicenter study

    Giant cell tumor of bone (GCTB) is an aggressive neoplasm typically occurring near joints in young individuals [ 1 ]. As an intermediate tumor rarely associated with pulmonary metastasis, it accounts for approximately 5% of all primary bone tumors …

  19. Open Access 15-06-2023 | Denosumab | OriginalPaper

    The efficacy and safety of short-course neoadjuvant denosumab for en bloc spondylectomy in spinal giant cell tumor of bone: a preliminary report

    Giant cell tumor of bone (GCTB) is a primary intermediate neoplasm with local aggressiveness [ 1 , 2 ]. Most tumor commonly occurs at extremity, where only 1.4–9.4% of the cases occur in the spine [ 3 , 4 ]. Spinal GCTB represents a special entity …

  20. Open Access 01-12-2022 | giant cell tumor | OriginalPaper

    Risk factors of fracture following curettage for bone giant cell tumors of the extremities

    Giant bone tumors of the bone (GCTB) are intermediate-grade primary bone tumors [ 1 ]. The standard treatment is usually intralesional curettage, because it can preserve the joint and improve postoperative function. Following curettage of GCTB, it …

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