A plasma phosphorylated-tau 217 immunoassay offers comparative diagnostic accuracy for Alzheimer’s disease pathologies to that of cerebrospinal fluid biomarkers, with a reduced need for advanced confirmatory testing.
Individuals with hearing loss may be at an increased risk for developing incident dementia, with additional risk in those people who do not use hearing aids.
Individuals diagnosed with coronary heart disease have an increased risk for developing all-cause dementia, Alzheimer’s disease, and vascular dementia in later life, particularly if diagnosed before the age of 45 years.
Our tailored content service will keep you up to date…
Receive newsletters curated for the busy specialist by our expert editorial team
Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
Huntington’s disease has no effective treatment to prevent progression and its involuntary motor symptoms but, in this 75-year-old patient, daily memantine has prevented chorea and disease progression for 5 years.
Clinical course and autopsy findings from two patients treated with aducanumab for Alzheimer's disease, shedding light on the time course of amyloid lowering and the potential impact of co-pathology on clinical response.
Alzheimer's disease (AD) is the most common form of dementia and also the predominant type of neurodegenerative disease [ 1 , 2 ]. The characteristics of AD include progressive cognitive impairment and behavioral disturbances, significantly …
Neurodegenerative diseases cause progressive deterioration in cognitive function by the loss of the activity of neurons in the brain. Worldwide, 10.2 million people suffer from neurodegenerative disorders, and the incidence is steadily increasing.
Evidence This study investigated the relationship between periodontal disease (PD) and Alzheimer’s Disease (AD) through a Systematic Literature Network Analysis (SLNA), combining bibliometric analysis with a Systematic Literature Review (SLR).
Neurodegenerative diseases refer to a group of diseases caused by chronic progressive degeneration of the central nervous system (CNS), mainly including Alzheimer’s disease(AD), Parkinson’s disease(PD), amyotrophic lateral sclerosis(ALS) …
Alzheimer's research and care is changing rapidly. Keep up with the latest developments from key international conferences, together with expert insights on how to integrate these advances into practice.
This content is intended for healthcare professionals outside of the UK.
PET biomarkers are fast becoming critical in the new era of disease modification for Alzheimer’s disease. Techniques around amyloid and tau require the expertise of nuclear medicine and radiology physicians to investigate and interpret PET scans in clinical settings. This program examines current and emerging biomarkers and assists in identifying patterns from different PET tracers in an interactive perceptual learning environment.
Neuroimaging plays an increasingly critical role in clinical practice. PET Pearls is an interactive activity designed to improve your confidence and accuracy when interpreting imaging for early signs of cognitive impairment.
Neurodegenerative diseases cause progressive deterioration in cognitive function by the loss of the activity of neurons in the brain. Worldwide, 10.2 million people suffer from neurodegenerative disorders, and the incidence is steadily increasing.
The prevalence of all-cause dementia increases exponentially from ages 65 to 85, doubling every 5 years [ 1 , 2 ], and continues to increase even after the age of 90 [ 3 ]. In a recent epidemiological study conducted in the province of Modena …
Evidence This study investigated the relationship between periodontal disease (PD) and Alzheimer’s Disease (AD) through a Systematic Literature Network Analysis (SLNA), combining bibliometric analysis with a Systematic Literature Review (SLR).
The noradrenergic nucleus Locus Coeruleus (LC) is precociously involved in Alzheimer’s Disease (AD) pathology, and its degeneration progresses during the course of the disease. Using Magnetic Resonance Imaging (MRI), researchers showed also in …