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Medical Oncology

Issue 6/2024

Content (37 Articles)

A new vision of the efficacy of both CAR-NK and CAR-T cells in treating cancers and autoimmune diseases

Salim Hussein Hassan, Mohammad Y. Alshahrani, Raed Obaid Saleh, Bahira Abdulrazzaq Mohammed, Abhinav Kumar, Sami G. Almalki, Adnan Taan Alkhafaji, Pallavi Ghildiyal, Ahmed Read Al-Tameemi, Ahmed Elawady

Role of the STING pathway in myeloid neoplasms: a prospero-registered systematic review of principal hurdles of STING on the road to the clinical practice

Leticia Rodrigues Sampaio, Ricardo Dyllan Barbosa Dias, João Vitor Caetano Goes, Renata Pinheiro Martins de Melo, Daniela de Paula Borges, Mayara Magna de Lima Melo, Roberta Taiane Germano de Oliveira, Howard Lopes Ribeiro-Júnior, Silvia Maria Meira Magalhães, Ronald Feitosa Pinheiro

Retraction Note

Retraction Note: Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway

Shengyou Ge, Kexin Wang, Yuxiang Meng, Zongxuan He, Xiaochen Yang, Wei Shang, Lin Wang

In silico and network pharmacology analysis of fucosterol: a potent anticancer bioactive compound against HCC

Kajal Singh, Pradeep Kumar, Amit Kumar Singh, Nancy Singh, Sakshi Singh, Kavindra Nath Tiwari, Shreni Agrawal, Richa Das, Anuradha Singh, Bhuwal Ram, Amit Kumar Tripathi, Sunil Kumar Mishra

Colorectal Cancer Original Paper

NLRX1: a key regulator in mitochondrial respiration and colorectal cancer progression

Yaxin Ding, Wenjie Sun, Mingwei Han, Ziyu Liu, Huarui Kang, Xiaohan Ma, Jiayu Wang, Hongrui Mu, Yuxiao Huang, Shiyuan Hou, Danni Sun, Xing Shen, Xingan Wu, Rongrong Liu

Lung Cancer Original Paper

Drug-loaded polymer-coated silver nanoparticles for lung cancer theranostics

Ranjita Misra, Subhenjit Hazra, Suraiya Saleem, Sushmitha Nehru

Head and Neck Cancer Review Article

Research progress of immunotherapy for advanced head and neck cancer

Anchi Sun, Zhiwei Xing, Rongrong Lv, Pengyuan Niu, Bao Zhao, Shiyin Ma, Hui Li

A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways

Md. Rezaul Islam, Abdur Rauf, Shopnil Alash, Md Naeem Hossain Fakir, Gazi Kaifeara Thufa, Mahbuba Sharmin Sowa, Dattatreya Mukherjee, Harendra Kumar, Md Sadique Hussain, Abdullah S. M. Aljohani, Muhammad Imran, Waleed Al Abdulmonem, Rekha Thiruvengadam, Muthu Thiruvengadam

Open Access Epigenetics Original Paper

Lung adenocarcinomas without driver genes converge to common adaptive strategies through diverse genetic, epigenetic, and niche construction evolutionary pathways

Robert A. Gatenby, Kimberly A. Luddy, Jamie K. Teer, Anders Berglund, Audrey R. Freischel, Ryan M. Carr, Amanda E. Lam, Kenneth J. Pienta, Sarah R. Amend, Robert H. Austin, Emma U. Hammarlund, John L. Cleveland, Kenneth Y. Tsai, Joel S. Brown

Metastasis Original Paper

CLIP170 inhibits the metastasis and EMT of papillary thyroid cancer through the TGF-β pathway

Binyuan Ma, Yaxin Xu, Hongwei Gao, Yinggui Yang, Yunyan Pan, Chongge You

Breast Cancer Original Paper

Glucagon-like peptide-1 analogs activate AMP kinase leading to reversal of the Warburg metabolic switch in breast cancer cells

Hagai Ligumsky, Sharon Amir, Tamar Arbel Rubinstein, Kate Guion, Tali Scherf, Avraham Karasik, Ido Wolf, Tami Rubinek

Sarcopenia Original Paper

Standardized phase angle: relationship with functionality, muscle mass and postoperative outcomes in surgical cancer patients

Jéssica Härter, Silvana Paiva Orlandi, Renata Moraes Bielemann, Leonardo Pozza dos Santos, Maria Cristina Gonzalez

Glioblastoma Original Paper

Altering biomolecular condensates as a potential mechanism that mediates cannabidiol effect on glioblastoma

Lei P. Wang, Pablo Shimaoka Chagas, Évila Lopes Salles, Sahar Emami Naeini, Jules Gouron, Hannah M. Rogers, Hesam Khodadadi, Bidhan Bhandari, Ahmet Alptekin, Xu Qin, Kumar Vaibhav, Vincenzo Costigliola, David C. Hess, Krishnan M. Dhandapani, Ali S. Arbab, Martin J. Rutkowski, Jack C. Yu, Babak Baban

Review Article

The role of IGFBP-3 in tumor development and progression: enlightenment for diagnosis and treatment

Yudi Wang, He Zhang, Xuehua Zhang, Peizheng Mu, Leilei Zhao, Ruomei Qi, Yurui Zhang, Xiao Zhu, Yucui Dong

Original Paper

Phytochemical profiling, cytotoxic, anti-migration, and anti-angiogenic potential of phenolic-rich fraction from Peganum harmala: in vitro and in ovo studies

Hadjer Kemel, Lamia Benguedouar, Djamel Boudjerda, Soumaya Menadi, Ercan Cacan, Mohamed Sifour

Cancer Therapy Review Article

Harnessing polyelectrolyte complexes for precision cancer targeting: a comprehensive review

Bhupendra G. Prajapati, Jai Bharti Sharma, Swapnil Sharma, Naitik D. Trivedi, Mansi Gaur, Devesh U. Kapoor

Lung Cancer Original Paper

A small molecule compound 759 inhibits the wnt/beta-catenin signaling pathway via increasing the Axin protein stability

Seunghan Sun, Young-Dae Gong, Jong Soon Kang, Mi-Sook Dong, Yongseok Choi

Gastric Cancer Original Article

Evaluation of the cytotoxic activities of the essential oil from Pistacia atlantica Desf. oleoresin on human gastric cancer cell lines

Fatemeh Saeedi, Mohammad Salehi, Mohammad Javad Kamali, Mahsa Aghajani Mir, Sohrab Kazemi, Fatemeh Shirafkan, Ebrahim Zabihi Neyshaburi, Reihaneh Moeeni, Narjes Gorji, Zahra Memariani

Effective delivery of anti-PD-L1 siRNA with human heavy chain ferritin (HFn) in acute myeloid leukemia cell lines

Misagh Rajabinejad, Reza Valadan, Mohsen Tehrani, Ahmad Najafi, Reza Negarandeh, Majid Saeedi, Hossein Asgarian-Omran

Open Access Kidney Cancer Original Paper

Tumor microenvironment and clinical efficacy of first line immunotherapy-based combinations in metastatic renal cell carcinoma

Enrico Sammarco, Martina Rossetti, Alessia Salfi, Adele Bonato, Paolo Viacava, Gianluca Masi, Luca Galli, Pinuccia Faviana

Prostate Cancer Original Paper

WDR1 promotes prostate cancer progression through Wnt/β-catenin signaling

Jinfeng Cheng, Dan Huo, Zhonghua Zhang, Jianqing Zhang, Bizhen Dong, Zhen Liu, Zhi Zhou, Yanjun Lu

Breast Cancer Original Paper

Ethanolic extract of Euphorbia royleana Boiss. reduces metastasis of breast cancer cells and inhibits tumor progression in vivo

Sheereen Gull, Fareeda Tasneem, Ishtiaq Ahmed, Muhammad Aamir Aslam, Asima Tayyeb, Luqman Abid, Muhammad Imran Arshad, Naveed Shahzad

Esophageal Cancer Original Paper

Rhein suppresses esophageal cancer development by regulating cell cycle through DNMT3B gene

Cheng Li, Jingjing Yu, Ying Feng, Xiaoxue Sun, Mingming Sun, Weihui Ni, Jun Shao, Baoxin Wang

Ovarian Cancer Original Paper

IL-6 regulates epithelial ovarian cancer EMT, invasion, and metastasis by modulating Let-7c and miR-200c through the STAT3/HIF-1α pathway

Qiao Yun Guo, Jiang Nan Song, Yu Meng Chen, Hai Ning Yuan, Wen Shu Xue, Yang Sun, Xiu long Niu, Yue Wang, Xiao Chen

Review Article

Insights into Nimbolide molecular crosstalk and its anticancer properties

Shabnum Shaheen, Sana Khalid, Khadija Aaliya, Ambreen Gul, Amna Hafeez, Muhammad Armaghan, Zainab M. Almarhoon, Daniela Calina, Khushbukhat Khan, Javad Sharifi-Rad

Review Article

Role of m6A modifications in immune evasion and immunotherapy

Chunyu Wu, Lvyuan Li, Qiling Tang, Qianjin Liao, Pan Chen, Can Guo, Zhaoyang Zeng, Wei Xiong

Original Paper

Therapeutic targeting of TNIK in papillary thyroid carcinoma: a novel approach for tumor growth suppression

Ruqian Zhang, Yongbo Yu, Yeran Yang, Meng Zhang, Xuan Zhang, Yan Chang, Shengcai Wang, Linfei Hu, Jiali Li, Xiangqian Zheng, Ruili Zhao, Yongli Guo, Xin Ni

NSCLC Review Article

PAQR4 oncogene: a novel target for cancer therapy

Dipti Patil, Swapnil Raut, Mitesh Joshi, Purvi Bhatt, Lokesh Kumar Bhatt

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine