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Journal of Cancer Research and Clinical Oncology

Issue 1/2020

Content (24 Articles)

Review – Cancer Research

Herbal nutraceuticals: safe and potent therapeutics to battle tumor hypoxia

Devarajan Nalini, Jayaraman Selvaraj, Ganesan Senthil Kumar

Review – Cancer Research

Hypoxia in solid tumors: a key promoter of cancer stem cell (CSC) resistance

Masoud Najafi, Bagher Farhood, Keywan Mortezaee, Ebrahim Kharazinejad, Jamal Majidpoor, Reza Ahadi

Cancer Fatigue Original Article – Cancer Research

Incorporation of Astragalus polysaccharides injection during concurrent chemoradiotherapy in advanced pharyngeal or laryngeal squamous cell carcinoma: preliminary experience of a phase II double-blind, randomized trial

Chia-Hsun Hsieh, Chien-Yu Lin, Cheng-Lung Hsu, Kang-Hsing Fan, Shiang-Fu Huang, Chun-Ta Liao, Li-Yu Lee, Shu-Kung Ng, Tzu-Chen Yen, Joseph Tung-Chieh Chang, Jr-Rung Lin, Hung-Ming Wang

NSCLC Original Article – Cancer Research

The comparison between adenocarcinoma and squamous cell carcinoma in lung cancer patients

Bing-Yen Wang, Jing-Yang Huang, Heng-Chung Chen, Ching-Hsiung Lin, Sheng-Hao Lin, Wei-Heng Hung, Ya-Fu Cheng

Open Access Gastric Cancer Original Article – Cancer Research

Sexual dimorphism in gastric cancer: tumor-associated neutrophils predict patient outcome only for women

Franziska Clausen, Hans-Michael Behrens, Sandra Krüger, Christoph Röcken

NSCLC Original Article – Cancer Research

Marital status independently predicts non-small cell lung cancer survival: a propensity-adjusted SEER database analysis

Zongwei Chen, Kanhua Yin, Difan Zheng, Jie Gu, Jizhuang Luo, Shuai Wang, Haiquan Chen

Open Access Gastric Cancer Original Article – Cancer Research

High gamma-glutamyl hydrolase and low folylpolyglutamate synthetase expression as prognostic biomarkers in patients with locally advanced gastric cancer who were administrated postoperative adjuvant chemotherapy with S-1

Yukio Maezawa, Kentaro Sakamaki, Naohide Oue, Yayoi Kimura, Itaru Hashimoto, Kentaro Hara, Kazuki Kano, Toru Aoyama, Yukihiko Hiroshima, Takanobu Yamada, Naoto Yamamoto, Takashi Ogata, Hiroyuki Ito, Haruhiko Cho, Manabu Shiozawa, Takaki Yoshikawa, Soichiro Morinaga, Yasushi Rino, Wataru Yasui, Munetaka Masuda, Yohei Miyagi, Takashi Oshima

Hepatocellular Carcinoma Original Article – Cancer Research

Candidate lncRNA–miRNA–mRNA network in predicting hepatocarcinogenesis with cirrhosis: an integrated bioinformatics analysis

Rui Zhang, Ying-yi Jiang, Kun Xiao, Xiao-quan Huang, Jian Wang, Shi-yao Chen

Uterine Sarcoma Original Article – Cancer Research

DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics

Felix K. F. Kommoss, Damian Stichel, Daniel Schrimpf, Mark Kriegsmann, Basile Tessier-Cloutier, Aline Talhouk, Jessica N. McAlpine, Kenneth T. E. Chang, Dominik Sturm, Stefan M. Pfister, Laura Romero-Pérez, Thomas Kirchner, Thomas G. P. Grünewald, Rolf Buslei, Hans-Peter Sinn, Gunhild Mechtersheimer, Peter Schirmacher, Dietmar Schmidt, Hans-Anton Lehr, Felix Sahm, David G. Huntsman, C. Blake Gilks, Friedrich Kommoss, Andreas von Deimling, Christian Koelsche

Rectal Cancer Original Article – Cancer Research

High expression of microRNA-199a-5p is associated with superior clinical outcomes in patients with locally advanced rectal cancer

Dong Won Baek, Gyeonghwa Kim, Byung Woog Kang, Hye Jin Kim, Su Yeon Park, Jun Seok Park, Gyu-Seog Choi, Min Kyu Kang, Keun Hur, Jong Gwang Kim

Glioblastoma Original Article – Cancer Research

Combined treatment of AT101 and demethoxycurcumin yields an enhanced anti-proliferative effect in human primary glioblastoma cells

Moiken Mehner, Carolin Kubelt, Vivian Adamski, Christina Schmitt, Michael Synowitz, Janka Held-Feindt

Ovarian Cancer Original Article – Cancer Research

High density of CD66b in primary high-grade ovarian cancer independently predicts response to chemotherapy

Alberto Posabella, Philipp Köhn, Alexandros Lalos, Alexander Wilhelm, Robert Mechera, Savas Soysal, Simone Muenst, Uwe Güth, Sylvia Stadlmann, Luigi Terracciano, Raoul A. Droeser, Jasmin Zeindler, Gad Singer

Lung Cancer Review – Clinical Oncology

Evolving the pulmonary nodules diagnosis from classical approaches to deep learning-aided decision support: three decades’ development course and future prospect

Bo Liu, Wenhao Chi, Xinran Li, Peng Li, Wenhua Liang, Haiping Liu, Wei Wang, Jianxing He

Nephrectomy Original Article – Clinical Oncology

The age-adjusted Charlson comorbidity index as a predictor of overall survival of surgically treated non-metastatic clear cell renal cell carcinoma

Ho Won Kang, Sung Min Kim, Won Tae Kim, Seok Joong Yun, Sang-Cheol Lee, Wun-Jae Kim, Eu Chang Hwang, Seok Ho Kang, Sung-Hoo Hong, Jinsoo Chung, Tae Gyun Kwon, Hyeon Hoe Kim, Cheol Kwak, Seok-Soo Byun, Yong-June Kim

NSCLC Original Article – Clinical Oncology

Microwave ablation as local consolidative therapy for patients with extracranial oligometastatic EGFR-mutant non-small cell lung cancer without progression after first-line EGFR-TKIs treatment

Yang Ni, Xin Ye, Xia Yang, Guanghui Huang, Wenhong Li, Jiao Wang, Xiaoying Han, Zhigang Wei, Min Meng

Open Access Rectal Cancer Original Article – Clinical Oncology

Precision oncotherapy based on liquid biopsies in multidisciplinary treatment of unresectable recurrent rectal cancer: a retrospective cohort study

Stefano Guadagni, Giammaria Fiorentini, Michele De Simone, Francesco Masedu, Odisseas Zoras, Andrew Reay Mackay, Donatella Sarti, Ioannis Papasotiriou, Panagiotis Apostolou, Marco Catarci, Marco Clementi, Enrico Ricevuto, Gemma Bruera

Prostate Cancer Original Article – Clinical Oncology

Postoperative biochemical recurrence of pathologically localized high-grade prostate cancer in adjuvant treatment-naïve patients

Ji Eun Heo, Jee Soo Park, Jong Soo Lee, Jongchan Kim, Won Sik Jang, Nam Hoon Cho, Koon Ho Rha, Young Deuk Choi, Sung Joon Hong, Won Sik Ham

Brachytherapy Original Article – Clinical Oncology

Safety and efficacy of CT-guided radioactive iodine-125 seed implantation assisted by a 3D printing template for the treatment of thoracic malignancies

Zhe Ji, Yuliang Jiang, Fuxin Guo, Ran Peng, Haitao Sun, Jinghong Fan, Fei Xu, Junjie Wang

Computed Tomography Original Article – Clinical Oncology

18F-FDG PET/CT versus CT/MR imaging for detection of neck lymph node metastasis in palpably node-negative oral cavity cancer

Mi Rye Bae, Jong-Lyel Roh, Jae Seung Kim, Jeong Hyun Lee, Kyung-Ja Cho, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim

Metastasis Original Article – Clinical Oncology

Clinical significance of a pvrl 4 encoded gene Nectin-4 in metastasis and angiogenesis for tumor relapse

Chinmayee Sethy, Kunal Goutam, Deepika Nayak, Rajalaxmi Pradhan, Sefinew Molla, Subhajit Chatterjee, Niranjan Rout, Michael D. Wyatt, Satya Narayan, Chanakya Nath Kundu

Open Access NSCLC Original Article – Clinical Oncology

Effects of single-nucleotide polymorphisms in the mTORC1 pathway on the risk of brain metastasis in patients with non-small cell lung cancer

Yiquan Xu, Yina Huang, Lihong Weng, Jiankun Zheng, Yi Huang, Ying Lin, Yunan Zhao, Hongru Li, Yusheng Chen

Metastasis Original Article – Clinical Oncology

A prospective observational study on the optimal maintenance strategy in HER2-positive advanced gastric cancer treated with trastuzumab-based therapy

Qian Li, Minzhi Lv, Huiqin Jiang, Yan Wang, Shan Yu, Wei Li, Yiyi Yu, Tianshu Liu

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.