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Editor's Choice

Neuropsychiatric involvement in pediatric SLE

Signs of neuropsychiatric systemic lupus erythematosus vary widely, from mild headache or anxiety to severe and life-threatening complications. Explore how to diagnose and tailor treatment.

Misdiagnosis of pulmonary artery sarcoma

Open Access Sarcoma Case Study

A pulmonary arterial sarcoma was mistaken as pulmonary vasculitis due to similarities between the diagnoses. This case highlights some cardinal features of the malignancy that are not seen in vasculitis.

Understanding bone metabolism in diabetes

Open Access Diabetes Review

Skeletal fragility in diabetes is associated with a significant clinical burden. Using diabetes-specific parameters may help address gaps in the assessment and management of diabetic bone disease.

Temporal artery ultrasound for diagnosis of giant cell arteritis

20-05-2024 Giant Cell Arteritis News

An ultrasound-first strategy can diagnose giant cell arteritis rapidly and effectively, and avoid the need for temporal artery biopsy in around two-fifths of cases.

Inflammatory rheumatic diseases and male reproductive health

Explore how chronic inflammation, physical restrictions, stress, and antirheumatic drugs may contribute to infertility and sexual dysfunction in men with IRDs.

Tapering synthetic DMARDs increases flare risk for some patients with RA

14-05-2024 Rheumatoid Arthritis News

Tapering conventional synthetic DMARD drugs to half dose or withdrawal in patients with sustained remission is associated with an increased risk for flare compared with stable treatment.

A challenging diagnosis of lung cancer

Open Access Lung Cancer Case Study

Although uncommon, lung cancer in patients with granulomatosis with polyangiitis can be difficult to diagnose due to similarities in imaging findings.

Pain catastrophizing in rheumatic diseases

Open Access Rheumatology Review

Pain is a fundamental aspect of rheumatic diseases and its reduction a key treatment target, but what’s known about pain catastrophizing in this setting and how does it impact overall health?

SGLT2 inhibitors show gout prevention benefit over sulfonylureas

30-04-2024 Gout News

SGLT2 inhibitors reduce the risk of incident gout and gout flares in patients with type 2 diabetes and offer cardiovascular benefits, compared with sulfonylureas.

Managing the VTE risk in patients with CTD-ILD

People with connective tissue disease-related interstitial lung disease have an increased risk for developing venous thromboembolisms. What risk factors do clinicians need to be aware of?

Delayed diagnosis of APAP in patient with dermatomyositis

Open Access Respiratory Medicine Case Study

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

Decoding statin-associated muscle symptoms

SAMS are the main reason statins are discontinued, but they range in severity and persistence. Learn about self-limited and autoimmune statin myopathy, the factors that impact them, and available treatment strategies.

Approaching bone health in patients with hypopituitarism

Hypopituitarism has a negative impact on bone health throughout life. Patients should be assessed for the presence of bone disorders as early treatment may prevent bone complications from developing.

Treating multisystem inflammatory syndrome in children

MIS-C is a relatively uncommon but severe pediatric complication associated with COVID-19, requiring rapid and intensive treatment. What are the most effective treatment strategies?

Abatacept shows promise for arthritis prevention

06-03-2024 Rheumatoid Arthritis News

APIPPRA trial suggests abatacept may reduce the risk of developing rheumatoid arthritis in high-risk individuals.

Can osteoporosis medications also treat osteoarthritis?

Open Access Osteoarthrosis Review

Some commonly used osteoporosis medications show promise as a treatment for osteoarthritis as they can reduce symptoms and disease progression in postmenopausal women.

Corticosteroids for hydrocephalus in neurosarcoidosis

Open Access Hydrocephalus Case Study

Hydrocephalus is a rare complication of neurosarcoidosis, usually requiring prompt high-dose IV corticosteroids and neurosurgical treatment. Neurosurgery can have severe complications, but select cases may be eligible for drug treatment only.

Denosumab associated with lower risk for incident diabetes

28-02-2024 Type 2 Diabetes News

People with osteoporosis who continue with denosumab after their first dose are less likely to develop diabetes than those who discontinue therapy.

Accelerating treatment of IL-1-mediated autoinflammatory diseases

Practical guidance on diagnosing and managing four systemic autoinflammatory diseases caused by increased IL-1 production – CAPS, TRAPS, MKD, and DIRA – based on recent European and American recommendations.

How to recognise rare Kawasaki disease in neonates

Open Access Kawasaki Disease Case Study

When newborns present with clinical signs such as rash, distal extremity desquamation, and cervical lymph adenitis, and simultaneous increases in peripheral blood leukocyte count and platelets, clinicians should be highly alert to KD even without fever.