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Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
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Neurology Peripheral Nervous System Disease

Peripheral Nervous System Disease
Type 2 Diabetes Review

The gut microbiota, gut–brain axis, and type 2 diabetes

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The gut microbiota and host communicate bidirectionally along the gut–brain axis to regulate glucose homeostasis, and evidence supports a role for dysbiosis of the gut microbiota in the development of type 2 diabetes.

Editor's Choice

Orthopnea secondary to brachial plexitis with bilateral diaphragmatic paralysis

Open Access Neuralgic Shoulder Amyotrophy Case Study

A unique and subtle presentation of brachial plexopathy highlights the need to explore the possibility of diaphragmatic paralysis in cases of new-onset orthopnea.

Vasculitic neuropathies

Peripheral Nervous System Disease Review

Nerve involvement in vasculitis can be part of a systemic syndrome affecting multiple organs, or be confined to the peripheral nerves making diagnosis more challenging. This review describes the clinical presentation, diagnosis, and options for treatment.

Chronic cough as a genetic neurological disorder? Insights from CANVAS

Open Access Cough Review

Current thinking on the mechanisms underlying chronic cough, and how this might fit with the existence of cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS), a genetically driven disorder that has cough as a frequent feature.

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Live Webinar | 02-05-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on sleep in brain health

Reserve your place

Live: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Sven Rupprecht
Dr. Renata Riha
Developed by: Springer Medicine

Case Studies

Orthopnea secondary to brachial plexitis with bilateral diaphragmatic paralysis

Open Access Neuralgic Shoulder Amyotrophy Case Study

A unique and subtle presentation of brachial plexopathy highlights the need to explore the possibility of diaphragmatic paralysis in cases of new-onset orthopnea.

Neurosyphilis presenting with Guillain–Barre syndrome

Open Access Neurosyphilis Case Study

The first electrodiagnostically confirmed case of syphilitic GBS without coexisting confounding infections. It highlights the importance of including syphilis in the differential diagnosis of any patient presenting with ascending polyradiculopathy.

Distinguishing Hoffman’s syndrome from other myopathies

Open Access Myopathy Case Study

Hoffmann’s syndrome is a rare form of hypothyroid myopathy in adults. Clinical hallmarks are pseudohypertrophy and weakness of the calf muscles in combination with elevated creatine kinase and thyroid stimulating hormone.

Current Reviews

Prevalence of lingual sensory impairment following bilateral sagittal split osteotomy: a systematic review and meta-analysis

Open Access Nerve Injury Review

Orthognathic surgery is a surgical procedure aimed at rectifying facial skeletal components and restoring the normal anatomical and functional connections in individuals with dentofacial skeletal abnormalities. These abnormalities derive from …

Clinical insights into traumatic injury of the inferior alveolar and lingual nerves: a comprehensive approach from diagnosis to therapeutic interventions

Open Access Neuropathic Pain Review

The osteotomy procedure for impacted wisdom teeth ranks among the most commonly executed dental surgical interventions on a global scale. The intricate anatomical proximity during wisdom tooth removal gives rise to reported injury rates of …

Infrapatellar branch of the saphenous nerve lesion following tibial nailing: it is possible to avoid it?

Incision Review

Intramedullary nailing is often the treatment of choice in case of closed tibial shaft fractures, as it allows an early rehabilitation and satisfactory functional outcomes along with a low complication rate [ 1 , 2 ]. Nevertheless, iatrogenic …

Diabetic Neuropathy: Pathophysiology Review

Diabetic Neuropathy Neuropathic Pain (A Abd-Elsayed, Section Editor)

Diabetic neuropathy is a complication of diabetes mellitus that results from the metabolic and vascular disturbances associated with diabetes. It has been shown that up to 50–66% of all diabetic patients develop some sort of diabetic neuropathy …
Alzheimer's Disease Independent Medical Education

Neuroimaging for Alzheimer’s disease: eLearning (Link opens in a new window)

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Neuroimaging plays an increasingly critical role in clinical practice. PET Pearls is an interactive activity designed to improve your confidence and accuracy when interpreting imaging for early signs of cognitive impairment.

Supported by: Lilly

Developed by: Springer Healthcare IME
Basal Ganglia Disorder Podcast

Episode 4: Stem cell therapy for PD

Listen now

A new era for managing Parkinson’s disease?

STEM-PD, the first in-human safety trial of stem cell therapy for Parkinson’s disease, began this year and marks a huge step forward for this type of treatment.

We talk to Prof. Malin Parmar about why stem cell therapy is such a good option for patients with Parkinson’s disease and get an update on the current status of the trial.

Dr. Malin Parmar

Further Reading

Rituximab in non-systemic vasculitic neuropathy: a single-center experience

Open Access Rituximab Original Research

Several new treatment options with improved side effect profiles compared to conventional chemotherapeutics for neurological autoimmune disorders, such as multiple sclerosis, but also for rare neuromuscular disorders, such as myasthenia gravis …

An in vitro model for postoperative cranial nerve dysfunction and a proposed method of rehabilitation with N-acetylcysteine microparticles

Open Access Acetylcysteine Miscellaneous

Surgical procedures conducted in the vicinity of peripheral nerves pose risks of injury to those nerves through iatrogenic factors such as compression or manipulation. While typically transient in nature, postoperative nerve dysfunction of cranial …

Prevalence of lingual sensory impairment following bilateral sagittal split osteotomy: a systematic review and meta-analysis

Open Access Nerve Injury Review

Orthognathic surgery is a surgical procedure aimed at rectifying facial skeletal components and restoring the normal anatomical and functional connections in individuals with dentofacial skeletal abnormalities. These abnormalities derive from …

A prospective case series to evaluate subcostal nerve injury with high-resolution ultrasound in posterior retroperitoneoscopic adrenalectomy

Open Access Adrenalectomy

A prospective single-center case series at the Radboud University Medical Center in Nijmegen was performed between April 2021 and November 2022. An a priori study protocol was written (See Appendix 1 ) and subsequently approved by the Medical …

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