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Journal of Medical Case Reports
Published in: Journal of Medical Case Reports 1/2021

Open Access 01-12-2021 | Cancer Biomarker | Case report

Ovarian mature cystic teratoma with malignant transformation: two case reports

Authors: Afsaneh Tehranian, Akram Ghahghaei-Nezamabadi, Akram Seifollahi, Sara Kasraei, Hamideh Dehghani-Nejad, Arezoo Maleki-Hajiagha

Published in: Journal of Medical Case Reports | Issue 1/2021

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Abstract

Background

Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols.

Case presentation

We reported two Iranian cases of MT of MCT with two different stages and prognosis. Our both cases presented the same symptoms, including chronic abdominal pain and distention, loss of appetite, and weight loss. In case number 1, despite the large size of the tumor, the disease was at stage Ia and had a good prognosis; while, case number 2 was at stage IIIc of the disease with a poor prognosis.

Conclusion

The stage of the disease is the most important prognostic factor, and early diagnosis and treatment are very critical for better survival.
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Metadata
Title
Ovarian mature cystic teratoma with malignant transformation: two case reports
Authors
Afsaneh Tehranian
Akram Ghahghaei-Nezamabadi
Akram Seifollahi
Sara Kasraei
Hamideh Dehghani-Nejad
Arezoo Maleki-Hajiagha
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2021
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-020-02594-4

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