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Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 1/2007

01-01-2007 | Original Article

Preoperative diagnosis of mature cystic teratoma with malignant transformation: analysis of imaging findings and clinical and laboratory data

Authors: Sung Bin Park, Jeong Kon Kim, Kyu-Rae Kim, Kyoung-Sik Cho

Published in: Archives of Gynecology and Obstetrics | Issue 1/2007

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Abstract

Purpose

To evaluate the factors including the imaging findings and clinical and laboratory data that were useful for diagnosing mature cystic teratomas with malignant transformation.

Materials and methods

In 11 patients, we analyzed the imaging findings by the CT and MR focused on the soft tissue components for the following characteristics: size; the angle between the soft tissue components and the inner wall of the cyst (acute or obtuse); the configuration of the inner border (regular or irregular); and enhancement as well as tumor size. Clinical and laboratory data such as age, serum SCC, CA-125, CA 19-9, and AFP, were also determined.

Results

In the analysis of the imaging findings, nine (82%) of all tumors had soft tissue components and eight (89%) of nine soft-tissue-containing tumors showed an obtuse angle between the soft tissue components and the inner wall of the cyst as well as enhancement. In nine (82%) of the study patients it was shown that the largest diameter of the tumor was larger than 9.9 cm and the patients were older than 45 years. In the results of the laboratory data, six (67%) of performed nine patients had a CA-125 elevation greater than 35 U/ml and three (75%) of performed four patients had a CA 19-9 elevation greater than 37 U/ml.

Conclusion

We suggest that preoperative diagnosis may be improved and available in cases of synthesized imaging findings with clinical and laboratory data.
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Metadata
Title
Preoperative diagnosis of mature cystic teratoma with malignant transformation: analysis of imaging findings and clinical and laboratory data
Authors
Sung Bin Park
Jeong Kon Kim
Kyu-Rae Kim
Kyoung-Sik Cho
Publication date
01-01-2007
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 1/2007
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-006-0213-4

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