Skip to main content
Top
Published in: Indian Journal of Pediatrics 5/2019

01-05-2019 | Tuberculosis | Review Article

Chest Tuberculosis in Children

Authors: Priyanka Naranje, Ashu Seith Bhalla, Poonam Sherwani

Published in: Indian Journal of Pediatrics | Issue 5/2019

Login to get access

Abstract

Chest is the commonest site of involvement by tuberculosis (TB) in children; lungs being the most frequently affected region, followed by nodes, pleura and chest wall. It is difficult to diagnose TB in children due to lack of overt symptoms and difficulty in obtaining samples for microbiological confirmation. Hence various imaging modalities play an important role in diagnostic algorithm as well as in follow-up after treatment. Standardization of chest radiograph reporting in context of clinically suspected TB is the need of the hour so as to suggest a proper diagnosis and avoid over-diagnosis. This article aims to discuss the imaging features of chest tuberculosis according to the site of involvement on various imaging modalities in the pediatric population.
Literature
1.
go back to reference Abel L, El-Baghdadi J, Bousfiha AA, Casanova JL, Schurr E. Human genetics of tuberculosis: a long and winding road. Philos Trans R Soc Lond Ser B Biol Sci. 2014;369:20130428.CrossRef Abel L, El-Baghdadi J, Bousfiha AA, Casanova JL, Schurr E. Human genetics of tuberculosis: a long and winding road. Philos Trans R Soc Lond Ser B Biol Sci. 2014;369:20130428.CrossRef
2.
go back to reference Swingler GH, du Toit G, Andronikou S, van der Merwe L, Zar HJ. Diagnostic accuracy of chest radiography in detecting mediastinal lymphadenopathy in suspected pulmonary tuberculosis. Arch Dis Child. 2005;90:1153–6.CrossRefPubMedPubMedCentral Swingler GH, du Toit G, Andronikou S, van der Merwe L, Zar HJ. Diagnostic accuracy of chest radiography in detecting mediastinal lymphadenopathy in suspected pulmonary tuberculosis. Arch Dis Child. 2005;90:1153–6.CrossRefPubMedPubMedCentral
3.
go back to reference Du Toit G, Swingler G, Iloni K. Observer variation in detecting lymphadenopathy on chest radiography. Int J Tuberc Lung Dis. 2002;6:814–7.PubMed Du Toit G, Swingler G, Iloni K. Observer variation in detecting lymphadenopathy on chest radiography. Int J Tuberc Lung Dis. 2002;6:814–7.PubMed
4.
go back to reference Kumar A, Gupta D, Nagaraja SB, et al. Updated national guidelines for pediatric tuberculosis in India, 2012. Indian Pediatr. 2013;50:301–6. Kumar A, Gupta D, Nagaraja SB, et al. Updated national guidelines for pediatric tuberculosis in India, 2012. Indian Pediatr. 2013;50:301–6.
5.
go back to reference Graham SM, Ahmed T, Amanullah F, et al. Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel. J Infect Dis. 2012;205:S199–208. Graham SM, Ahmed T, Amanullah F, et al. Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel. J Infect Dis. 2012;205:S199–208.
6.
go back to reference Bhalla AS, Goyal A, Guleria R, Gupta AK. Chest tuberculosis: Radiological review and imaging recommendations. Indian J Radiol Imaging. 2015;25:213–25. Bhalla AS, Goyal A, Guleria R, Gupta AK. Chest tuberculosis: Radiological review and imaging recommendations. Indian J Radiol Imaging. 2015;25:213–25.
7.
go back to reference Concepcion NDP, Laya BF, Andronikou S, et al. Standardized radiographic interpretation of thoracic tuberculosis in children. Pediatr Radiol. 2017;47:1237–48. Concepcion NDP, Laya BF, Andronikou S, et al. Standardized radiographic interpretation of thoracic tuberculosis in children. Pediatr Radiol. 2017;47:1237–48.
8.
go back to reference Sodhi KS, Bhalla AS, Mahomed N, Laya BF. Imaging of thoracic tuberculosis in children: current and future directions. Pediatr Radiol. 2017;47:1260–8.CrossRefPubMed Sodhi KS, Bhalla AS, Mahomed N, Laya BF. Imaging of thoracic tuberculosis in children: current and future directions. Pediatr Radiol. 2017;47:1260–8.CrossRefPubMed
9.
go back to reference Bosch-Marcet J, Serres-Créixams X, Zuasnabar-Cotro A, Codina-Puig X, Català-Puigbó M, Simon-Riazuelo JL. Comparison of ultrasound with plain radiography and CT for the detection of mediastinal lymphadenopathy in children with tuberculosis. Pediatr Radiol. 2004;34:895–900.CrossRefPubMed Bosch-Marcet J, Serres-Créixams X, Zuasnabar-Cotro A, Codina-Puig X, Català-Puigbó M, Simon-Riazuelo JL. Comparison of ultrasound with plain radiography and CT for the detection of mediastinal lymphadenopathy in children with tuberculosis. Pediatr Radiol. 2004;34:895–900.CrossRefPubMed
10.
go back to reference Lew WJ, Jung YJ, Song JW, et al. Combined use of QuantiFERON-TB gold assay and chest computed tomography in a tuberculosis outbreak. Int J Tuberc Lung Dis. 2009;13:633–9. Lew WJ, Jung YJ, Song JW, et al. Combined use of QuantiFERON-TB gold assay and chest computed tomography in a tuberculosis outbreak. Int J Tuberc Lung Dis. 2009;13:633–9.
11.
go back to reference Veedu PT, Bhalla AS, Vishnubhatla S, et al. Pediatric vs adult pulmonary tuberculosis: a retrospective computed tomography study. World J Clin Pediatr. 2013;2:70–6. Veedu PT, Bhalla AS, Vishnubhatla S, et al. Pediatric vs adult pulmonary tuberculosis: a retrospective computed tomography study. World J Clin Pediatr. 2013;2:70–6.
12.
go back to reference Mukund A, Khurana R, Bhalla AS, Gupta AK, Kabra SK. CT patterns of nodal disease in pediatric chest tuberculosis. World J Radiol. 2011;3:17–23. Mukund A, Khurana R, Bhalla AS, Gupta AK, Kabra SK. CT patterns of nodal disease in pediatric chest tuberculosis. World J Radiol. 2011;3:17–23.
13.
go back to reference Kaur R, Jana M. Imaging in chest tuberculosis. In: Bhalla AS, Jana M, editors. Clinico-Radiological Series: Imaging of Chest Infections, 1st ed. New Delhi: Jaypee Brothers Medical Publishers; 2018. p. 124–45. Kaur R, Jana M. Imaging in chest tuberculosis. In: Bhalla AS, Jana M, editors. Clinico-Radiological Series: Imaging of Chest Infections, 1st ed. New Delhi: Jaypee Brothers Medical Publishers; 2018. p. 124–45.
15.
go back to reference Naranje P, Guleria R. Imaging of infections of pleura and chest wall. In: Bhalla AS, Jana M, editors. Clinico Radiological Series: Imaging of Chest Infections, 1st ed. New Delhi: Jaypee Brothers Medical Publishers; 2018. p. 385–403. Naranje P, Guleria R. Imaging of infections of pleura and chest wall. In: Bhalla AS, Jana M, editors. Clinico Radiological Series: Imaging of Chest Infections, 1st ed. New Delhi: Jaypee Brothers Medical Publishers; 2018. p. 385–403.
16.
go back to reference Arora A, Bhalla AS, Jana M, Sharma R. Overview of airway involvement in tuberculosis. J Med Imaging Radiat Oncol. 2013;57:576–81.CrossRefPubMed Arora A, Bhalla AS, Jana M, Sharma R. Overview of airway involvement in tuberculosis. J Med Imaging Radiat Oncol. 2013;57:576–81.CrossRefPubMed
17.
go back to reference Rizzi EB, Schinina' V, Cristofaro M, et al. Detection of pulmonary tuberculosis: comparing MR imaging with HRCT. BMC Infect Dis. 2011;11:243.CrossRef Rizzi EB, Schinina' V, Cristofaro M, et al. Detection of pulmonary tuberculosis: comparing MR imaging with HRCT. BMC Infect Dis. 2011;11:243.CrossRef
19.
go back to reference Baez JC, Ciet P, Mulkern R, Seethamraju RT, Lee EY. Pediatric chest MR imaging: lung and airways. Magn Reson Imaging Clin N Am. 2015;23:337–49.CrossRefPubMed Baez JC, Ciet P, Mulkern R, Seethamraju RT, Lee EY. Pediatric chest MR imaging: lung and airways. Magn Reson Imaging Clin N Am. 2015;23:337–49.CrossRefPubMed
20.
go back to reference Sodhi KS, Khandelwal N, Saxena AK, et al. Rapid lung MRI in children with pulmonary infections: time to change our diagnostic algorithms. J Magn Reson Imaging. 2016;43:1196–206. Sodhi KS, Khandelwal N, Saxena AK, et al. Rapid lung MRI in children with pulmonary infections: time to change our diagnostic algorithms. J Magn Reson Imaging. 2016;43:1196–206.
21.
go back to reference Vorster M, Sathekge MM, Bomanji J. Advances in imaging of tuberculosis: the role of 18F-FDG PET and PET/CT. Curr Opin Pulm Med. 2014;20:287–93.CrossRefPubMed Vorster M, Sathekge MM, Bomanji J. Advances in imaging of tuberculosis: the role of 18F-FDG PET and PET/CT. Curr Opin Pulm Med. 2014;20:287–93.CrossRefPubMed
22.
go back to reference Pelletier-Galarneau M, Martineau P, Zuckier LS, Pham X, Lambert R, Turpin S. 18F-FDG-PET/CT imaging of thoracic and extrathoracic tuberculosis in children. Semin Nucl Med. 2017;47:304–18.CrossRefPubMed Pelletier-Galarneau M, Martineau P, Zuckier LS, Pham X, Lambert R, Turpin S. 18F-FDG-PET/CT imaging of thoracic and extrathoracic tuberculosis in children. Semin Nucl Med. 2017;47:304–18.CrossRefPubMed
23.
go back to reference Willowson KP, Bailey EA, Bailey DL. A retrospective evaluation of radiation dose associated with low dose FDG protocols in whole-body PET/CT. Australas Phys Eng Sci Med. 2012;35:49–53.CrossRefPubMed Willowson KP, Bailey EA, Bailey DL. A retrospective evaluation of radiation dose associated with low dose FDG protocols in whole-body PET/CT. Australas Phys Eng Sci Med. 2012;35:49–53.CrossRefPubMed
Metadata
Title
Chest Tuberculosis in Children
Authors
Priyanka Naranje
Ashu Seith Bhalla
Poonam Sherwani
Publication date
01-05-2019
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 5/2019
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-018-02847-7

Other articles of this Issue 5/2019

Indian Journal of Pediatrics 5/2019 Go to the issue