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01-08-2015 | Review Article

Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction

Authors: Ulrike Attenberger, Ciprian Catana, Hersh Chandarana, Onofrio A Catalano, Kent Friedman, Stefan A Schonberg, James Thrall, Marco Salvatore, Bruce R. Rosen, Alexander R. Guimaraes

Published in: Abdominal Radiology | Issue 6/2015

Abstract

Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.

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Title: Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction
Authors: Ulrike Attenberger
Ciprian Catana
Hersh Chandarana
Onofrio A Catalano
Kent Friedman
Stefan A Schonberg
James Thrall
Marco Salvatore
Bruce R. Rosen
Alexander R. Guimaraes
Publication date: 01-08-2015
Publisher: Springer US
Published in: Abdominal Radiology / Issue 6/2015
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-015-0455-3

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Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction

Abstract

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