Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
European Radiology
Published in: European Radiology 6/2013

01-06-2013 | Computed Tomography

Iterative reconstruction techniques for computed tomography part 2: initial results in dose reduction and image quality

Authors: Martin J. Willemink, Tim Leiner, Pim A. de Jong, Linda M. de Heer, Rutger A. J. Nievelstein, Arnold M. R. Schilham, Ricardo P. J. Budde

Published in: European Radiology | Issue 6/2013

Login to get access

Abstract

Objectives

To present the results of a systematic literature search aimed at determining to what extent the radiation dose can be reduced with iterative reconstruction (IR) for cardiopulmonary and body imaging with computed tomography (CT) in the clinical setting and what the effects on image quality are with IR versus filtered back-projection (FBP) and to provide recommendations for future research on IR.

Methods

We searched Medline and Embase from January 2006 to January 2012 and included original research papers concerning IR for CT.

Results

The systematic search yielded 380 articles. Forty-nine relevant studies were included. These studies concerned: the chest(n = 26), abdomen(n = 16), both chest and abdomen(n = 1), head(n = 4), spine(n = 1), and no specific area (n = 1). IR reduced noise and artefacts, and it improved subjective and objective image quality compared to FBP at the same dose. Conversely, low-dose IR and normal-dose FBP showed similar noise, artefacts, and subjective and objective image quality. Reported dose reductions ranged from 23 to 76 % compared to locally used default FBP settings. However, IR has not yet been investigated for ultra-low-dose acquisitions with clinical diagnosis and accuracy as endpoints.

Conclusion

Benefits of IR include improved subjective and objective image quality as well as radiation dose reduction while preserving image quality. Future studies need to address the value of IR in ultra-low-dose CT with clinically relevant endpoints.

Key Points

• Iterative reconstruction improves image quality of CT images at equal acquisition parameters.
• IR preserves image quality compared to normal-dose filtered back-projection.
• The reduced radiation dose made possible by IR is advantageous for patients.
• IR has not yet been investigated with clinical diagnosis and accuracy as endpoints.
Appendix
Available only for authorised users
Literature
1.
Fleischmann D, Boas FE (2011) Computed tomography—old ideas and new technology. Eur Radiol 21:510–517PubMedCrossRef
2.
Pan X, Sidky EY, Vannier M (2009) Why do commercial CT scanners still employ traditional, filtered back-projection for image reconstruction? Inverse Probl 25:1230009PubMedCrossRef
3.
Nelson RC, Feuerlein S, Boll DT (2011) New iterative reconstruction techniques for cardiovascular computed tomography: how do they work, and what are the advantages and disadvantages? J Cardiovasc Comput Tomogr 5:286–292PubMedCrossRef
4.
Bittencourt MS, Schmidt B, Seltmann M et al (2011) Iterative reconstruction in image space (IRIS) in cardiac computed tomography: initial experience. Int J Cardiovasc Imaging 27:1081–1087PubMedCrossRef
5.
Leipsic J, Labounty TM, Heilbron B et al (2010) Adaptive statistical iterative reconstruction: assessment of image noise and image quality in coronary CT angiography. AJR Am J Roentgenol 195:649–654PubMedCrossRef
6.
Renker M, Nance JW Jr, Schoepf UJ et al (2011) Evaluation of heavily calcified vessels with coronary CT angiography: comparison of iterative and filtered back projection image reconstruction. Radiology 260:390–399PubMedCrossRef
7.
Utsunomiya D, Weigold WG, Weissman G, Taylor AJ (2011) Effect of hybrid iterative reconstruction technique on quantitative and qualitative image analysis at 256-slice prospective gating cardiac CT. Eur Radiol 22:1287–1294PubMedCrossRef
8.
Leipsic J, Heilbron BG, Hague C (2012) Iterative reconstruction for coronary CT angiography: finding its way. Int J Cardiovasc Imaging 28:613–620PubMedCrossRef
9.
Liberati A, Altman DG, Tetzlaff J et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med 151:W65–W94PubMedCrossRef
10.
Månsson LG (2000) Methods for the evaluation of image quality: a review. Radiat Prot Dosim 90:89–99CrossRef
11.
Mieville FA, Gudinchet F, Rizzo E et al (2011) Paediatric cardiac CT examinations: impact of the iterative reconstruction method ASIR on image quality—preliminary findings. Pediatr Radiol 41:1154–1164PubMedCrossRef
12.
Sund P, Bath M, Kheddache S, Mansson LG (2004) Comparison of visual grading analysis and determination of detective quantum efficiency for evaluating system performance in digital chest radiography. Eur Radiol 14:48–58PubMedCrossRef
13.
Habets J, Symersky P, de Mol BA, Mali WP, Leiner T, Budde RP (2012) A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves. Int J Cardiovasc Imaging 28:1567–1575PubMedCrossRef
14.
Mueck FG, Korner M, Scherr MK et al (2011) Upgrade to Iterative Image Reconstruction (IR) in Abdominal MDCT Imaging: a clinical study for detailed parameter optimization beyond vendor recommendations using the Adaptive Statistical Iterative Reconstruction Environment (ASIR). Rofo 184:229–238PubMed
15.
Funama Y, Taguchi K, Utsunomiya D et al (2011) Combination of a low-tube-voltage technique with hybrid iterative reconstruction (iDose) algorithm at coronary computed tomographic angiography. J Comput Assist Tomogr 35:480–485PubMedCrossRef
16.
Kambadakone AR, Chaudhary NA, Desai GS, Nguyen DD, Kulkarni NM, Sahani DV (2011) Low-dose MDCT and CT enterography of patients with Crohn disease: feasibility of adaptive statistical iterative reconstruction. AJR Am J Roentgenol 196:W743–W752PubMedCrossRef
17.
Hara AK, Paden RG, Silva AC, Kujak JL, Lawder HJ, Pavlicek W (2009) Iterative reconstruction technique for reducing body radiation dose at CT: feasibility study. AJR Am J Roentgenol 193:764–771PubMedCrossRef
18.
Schindera ST, Diedrichsen L, Muller HC et al (2011) Iterative reconstruction algorithm for abdominal multidetector CT at different tube voltages: assessment of diagnostic accuracy, image quality, and radiation dose in a phantom study. Radiology 260:454–462PubMedCrossRef
19.
Bulla S, Blanke P, Hassepass F et al (2012) Reducing the radiation dose for low-dose CT of the paranasal sinuses using iterative reconstruction: feasibility and image quality. Eur J Radiol 81:2246–2250PubMedCrossRef
20.
Leipsic J, Labounty TM, Heilbron B et al (2010) Estimated radiation dose reduction using adaptive statistical iterative reconstruction in coronary CT angiography: the ERASIR study. AJR Am J Roentgenol 195:655–660PubMedCrossRef
21.
Prakash P, Kalra MK, Digumarthy SR et al (2010) Radiation dose reduction with chest computed tomography using adaptive statistical iterative reconstruction technique: initial experience. J Comput Assist Tomogr 34:40–45PubMedCrossRef
22.
Renker M, Ramachandra A, Schoepf UJ et al (2011) Iterative image reconstruction techniques: applications for cardiac CT. J Cardiovasc Comput Tomogr 5:225–230PubMedCrossRef
23.
Marin D, Nelson RC, Schindera ST et al (2010) Low-tube-voltage, high-tube-current multidetector abdominal CT: improved image quality and decreased radiation dose with adaptive statistical iterative reconstruction algorithm—initial clinical experience. Radiology 254:145–153PubMedCrossRef
24.
Kilic K, Erbas G, Guryildirim M, Arac M, Ilgit E, Coskun B (2011) Lowering the dose in head CT using adaptive statistical iterative reconstruction. AJNR Am J Neuroradiol 32:1578–1582PubMedCrossRef
25.
Mitsumori LM, Shuman WP, Busey JM, Kolokythas O, Koprowicz KM (2012) Adaptive statistical iterative reconstruction versus filtered back projection in the same patient: 64 channel liver CT image quality and patient radiation dose. Eur Radiol 22:138–143PubMedCrossRef
26.
Park EA, Lee W, Kim KW et al (2012) Iterative reconstruction of dual-source coronary CT angiography: assessment of image quality and radiation dose. Int J Cardiovasc Imaging 28:1775–1786PubMedCrossRef
27.
Sagara Y, Hara AK, Pavlicek W, Silva AC, Paden RG, Wu Q (2010) Abdominal CT: comparison of low-dose CT with adaptive statistical iterative reconstruction and routine-dose CT with filtered back projection in 53 patients. AJR Am J Roentgenol 195:713–719PubMedCrossRef
28.
Lee SJ, Park SH, Kim AY et al (2011) A prospective comparison of standard-dose CT enterography and 50 % reduced-dose CT enterography with and without noise reduction for evaluating Crohn disease. AJR Am J Roentgenol 197:50–57PubMedCrossRef
29.
Cornfeld D, Israel G, Detroy E, Bokhari J, Mojibian H (2011) Impact of Adaptive Statistical Iterative Reconstruction (ASIR) on radiation dose and image quality in aortic dissection studies: a qualitative and quantitative analysis. AJR Am J Roentgenol 196:W336–W340PubMedCrossRef
30.
Vorona GA, Ceschin RC, Clayton BL, Sutcavage T, Tadros SS, Panigrahy A (2011) Reducing abdominal CT radiation dose with the adaptive statistical iterative reconstruction technique in children: a feasibility study. Pediatr Radiol 41:1174–1182PubMedCrossRef
31.
Prakash P, Kalra MK, Kambadakone AK et al (2010) Reducing abdominal CT radiation dose with adaptive statistical iterative reconstruction technique. Investig Radiol 45:202–210CrossRef
32.
Flicek KT, Hara AK, Silva AC, Wu Q, Peter MB, Johnson CD (2010) Reducing the radiation dose for CT colonography using adaptive statistical iterative reconstruction: a pilot study. AJR Am J Roentgenol 195:126–131PubMedCrossRef
33.
Pontana F, Duhamel A, Pagniez J et al (2011) Chest computed tomography using iterative reconstruction vs filtered back projection (Part 2): image quality of low-dose CT examinations in 80 patients. Eur Radiol 21:636–643PubMedCrossRef
34.
Korn A, Fenchel M, Bender B et al (2011) Iterative reconstruction in head CT: image quality of routine and Low-dose protocols in comparison with standard filtered back-projection. AJNR Am J Neuroradiol 33:218–224PubMedCrossRef
35.
Sato J, Akahane M, Inano S et al (2011) Effect of radiation dose and adaptive statistical iterative reconstruction on image quality of pulmonary computed tomography. Jpn J Radiol 30:146–153PubMedCrossRef
36.
May MS, Wust W, Brand M et al (2011) Dose reduction in abdominal computed tomography: intraindividual comparison of image quality of full-dose standard and half-dose iterative reconstructions with dual-source computed tomography. Investig Radiol 46:465–470CrossRef
37.
Winklehner A, Karlo C, Puippe G et al (2011) Raw data-based iterative reconstruction in body CTA: evaluation of radiation dose saving potential. Eur Radiol 21:2521–2526PubMedCrossRef
38.
Moscariello A, Takx RA, Schoepf UJ et al (2011) Coronary CT angiography: image quality, diagnostic accuracy, and potential for radiation dose reduction using a novel iterative image reconstruction technique-comparison with traditional filtered back projection. Eur Radiol 21:2130–2138PubMedCrossRef
39.
Gervaise A, Osemont B, Lecocq S et al (2012) CT image quality improvement using adaptive iterative dose reduction with wide-volume acquisition on 320-detector CT. Eur Radiol 22:295–301PubMedCrossRef
40.
41.
42.
Christner JA, Kofler JM, McCollough CH (2010) Estimating effective dose for CT using dose-length product compared with using organ doses: consequences of adopting International Commission on Radiological Protection publication 103 or dual-energy scanning. AJR Am J Roentgenol 194:881–889PubMedCrossRef
43.
Prakash P, Kalra MK, Ackman JB et al (2010) Diffuse lung disease: CT of the chest with adaptive statistical iterative reconstruction technique. Radiology 256:261–269PubMedCrossRef
44.
Hu XH, Ding XF, Wu RZ, Zhang MM (2011) Radiation dose of non-enhanced chest CT can be reduced 40 % by using iterative reconstruction in image space. Clin Radiol 66:1023–1029PubMedCrossRef
45.
Leipsic J, Nguyen G, Brown J, Sin D, Mayo JR (2010) A prospective evaluation of dose reduction and image quality in chest CT using adaptive statistical iterative reconstruction. AJR Am J Roentgenol 195:1095–1099PubMedCrossRef
46.
Pontana F, Pagniez J, Flohr T et al (2011) Chest computed tomography using iterative reconstruction vs filtered back projection (Part 1): Evaluation of image noise reduction in 32 patients. Eur Radiol 21:627–635PubMedCrossRef
47.
Yanagawa M, Honda O, Kikuyama A et al (2012) Pulmonary nodules: Effect of adaptive statistical iterative reconstruction (ASIR) technique on performance of a computer-aided detection (CAD) system-Comparison of performance between different-dose CT scans. Eur J Radiol 81:2877–2886
48.
Min JK, Swaminathan RV, Vass M, Gallagher S, Weinsaft JW (2009) High-definition multidetector computed tomography for evaluation of coronary artery stents: comparison to standard-definition 64-detector row computed tomography. J Cardiovasc Comput Tomogr 3:246–251PubMedCrossRef
49.
50.
Mayo JR, Aldrich J, Muller NL (2003) Radiation exposure at chest CT: a statement of the Fleischner Society. Radiology 228:15–21PubMedCrossRef
51.
Yanagawa M, Honda O, Yoshida S et al (2010) Adaptive statistical iterative reconstruction technique for pulmonary CT: image quality of the cadaveric lung on standard- and reduced-dose CT. Acad Radiol 17:1259–1266PubMedCrossRef
52.
Singh S, Kalra MK, Hsieh J et al (2010) Abdominal CT: comparison of adaptive statistical iterative and filtered back projection reconstruction techniques. Radiology 257:373–383PubMedCrossRef
53.
Martinsen AC, Saether HK, Hol PK, Olsen DR, Skaane P (2012) Iterative reconstruction reduces abdominal CT dose. Eur J Radiol 81:1483–1487PubMedCrossRef
54.
Matsuda I, Hanaoka S, Akahane M et al (2010) Adaptive statistical iterative reconstruction for volume-rendered computed tomography portovenography: improvement of image quality. Jpn J Radiol 28:700–706PubMedCrossRef
55.
Gosling O, Loader R, Venables P et al (2010) A comparison of radiation doses between state-of-the-art multislice CT coronary angiography with iterative reconstruction, multislice CT coronary angiography with standard filtered back-projection and invasive diagnostic coronary angiography. Heart 96:922–926PubMedCrossRef
56.
Scheffel H, Stolzmann P, Schlett CL et al (2011) Coronary artery plaques: Cardiac CT with model-based and adaptive-statistical iterative reconstruction technique. Eur J Radiol 81:e363–e369PubMedCrossRef
57.
Honda O, Yanagawa M, Inoue A et al (2011) Image quality of multiplanar reconstruction of pulmonary CT scans using adaptive statistical iterative reconstruction. Br J Radiol 84:335–341PubMedCrossRef
58.
Singh S, Kalra MK, Gilman MD et al (2011) Adaptive statistical iterative reconstruction technique for radiation dose reduction in chest CT: a pilot study. Radiology 259:565–573PubMedCrossRef
59.
Noel PB, Fingerle AA, Renger B, Munzel D, Rummeny EJ, Dobritz M (2011) Initial performance characterization of a clinical noise-suppressing reconstruction algorithm for MDCT. AJR Am J Roentgenol 197:1404–1409PubMedCrossRef
Metadata
Title
Iterative reconstruction techniques for computed tomography part 2: initial results in dose reduction and image quality
Authors
Martin J. Willemink
Tim Leiner
Pim A. de Jong
Linda M. de Heer
Rutger A. J. Nievelstein
Arnold M. R. Schilham
Ricardo P. J. Budde
Publication date
01-06-2013
Publisher
Springer-Verlag
Published in
European Radiology / Issue 6/2013
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-012-2764-z

Other articles of this Issue 6/2013

European Radiology 6/2013 Go to the issue

Musculoskeletal

Normal anatomical variants of the labrum of the hip at magnetic resonance imaging: a systematic review

Computed Tomography

Iterative reconstruction techniques for computed tomography Part 1: Technical principles

Neuro

Imaging of the entire cerebrospinal fluid volume with a multistation 3D SPACE MR sequence: feasibility study in patients with hydrocephalus

Cardiac

Precision of pulmonary vein diameter measurements assessed by CE-MRA and steady-state-free precession imaging

Neuro

Value of CT angiography for the detection of intracranial vascular lesions in patients with acute severe headache

Ultrasound

Evaluation of distal turbulence intensity for the detection of both plaque ulceration and stenosis grade in the carotid bifurcation using clinical Doppler ultrasound