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Journal of Cancer Research and Clinical Oncology

Issue 4/2019

Content (26 Articles)

Targeted Therapy Review – Cancer Research

Novel insights into the role of aptamers in the fight against cancer

Yasen Maimaitiyiming, De Fei Hong, Chang Yang, Hua Naranmandura

Metastasis Original Article – Cancer Research

A three-gene methylation marker panel for the nodal metastatic risk assessment of muscle-invasive bladder cancer

Beatrice Stubendorff, Kerstin Wilhelm, Kathleen Posselt, James Catto, Arndt Hartmann, Simone Bertz, Susanne Füssel, Vladimir Novotny, Marieta Toma, Mieczyslaw Gajda, Jan Lehmann, Heiko Wunderlich, Marc-Oliver Grimm, Michael Stöckle, Kerstin Junker

Breast Cancer Original Article – Cancer Research

Differential molecular pathways expression in HER2 positive early breast cancer according to hormone receptor status

Claudia Omarini, Stefania Bettelli, Cecilia Caprera, Samantha Manfredini, Monica Barbolini, Luca Moscetti, Chrystel Isca, Angela Toss, Elena Barbieri, Laura Cortesi, Shaniko Kaleci, Antonino Maiorana, Giovanni Tazzioli, Stefano Cascinu, Federico Piacentini

Oral Cancer Original Article – Cancer Research

Computer-assisted medical image classification for early diagnosis of oral cancer employing deep learning algorithm

Pandia Rajan Jeyaraj, Edward Rajan Samuel Nadar

Astrocytoma Original Article – Cancer Research

High frequency of H3 K27M mutations in adult midline gliomas

Azadeh Ebrahimi, Marco Skardelly, Martin U. Schuhmann, Martin Ebinger, David Reuss, Manuela Neumann, Ghazaleh Tabatabai, Patricia Kohlhof-Meinecke, Jens Schittenhelm

Original Article – Cancer Research

Pathobiological role of cleft palate transmembrane protein 1 family proteins in oral squamous cell carcinoma

Keisuke Inoue, Kiichi Hatano, Yuki Hanamatsu, Chiemi Saigo, Yusuke Kito, Katsuaki Bunai, Toshiyuki Shibata, Tamotsu Takeuchi

NSCLC Original Article – Cancer Research

GLRX inhibition enhances the effects of geftinib in EGFR-TKI-resistant NSCLC cells through FoxM1 signaling pathway

Linlin Wang, Jing Liu, Jinguo Liu, Xiaoyan Chen, Meijia Chang, Jing Li, Jian Zhou, Chunxue Bai, Yuanlin Song

NSCLC Original Article – Cancer Research

Prevalence and clinical significance of RBM3 immunostaining in non-small cell lung cancers

Nathaniel Melling, Kai Bachmann, Bianca Hofmann, Alexander Tarek El Gammal, Matthias Reeh, Oliver Mann, Christoph Moebius, Marco Blessmann, Jakob Robert Izbicki, Katharina Grupp

Rhabdomyosarcoma Original Article – Cancer Research

NRF2 orchestrates the redox regulation induced by radiation therapy, sustaining embryonal and alveolar rhabdomyosarcoma cells radioresistance

Francesco Marampon, Silvia Codenotti, Francesca Megiorni, Andrea Del Fattore, Simona Camero, Giovanni Luca Gravina, Claudio Festuccia, Daniela Musio, Francesca De Felice, Valerio Nardone, Anna Natalizia Santoro, Carlo Dominici, Alessandro Fanzani, Luigi Pirtoli, Antonella Fioravanti, Vincenzo Tombolini, Sara Cheleschi, Paolo Tini

Open Access Metastasis Original Article – Cancer Research

Insufficient radiofrequency ablation promotes the metastasis of residual hepatocellular carcinoma cells via upregulating flotillin proteins

Ning Zhang, Hui Li, Chengdong Qin, Dening Ma, Yiming Zhao, Weiping Zhu, Lu Wang

Open Access Ovarian Cancer Original Article – Cancer Research

Expression of Syk and MAP4 proteins in ovarian cancer

Siwei Zhang, Suha Deen, Sarah J. Storr, Anqi Yao, Stewart G. Martin

Circumcision Original Article – Cancer Research

Adherence to the EAU guidelines on Penile Cancer Treatment: European, multicentre, retrospective study

Maida Bada, Francesco Berardinelli, Peter Nyiràdy, Judith Varga, Pasquale Ditonno, Michele Battaglia, Paolo Chiodini, Cosimo De Nunzio, Giorgia Tema, Alessandro Veccia, Alessandro Antonelli, Luca Cindolo, Claudio Simeone, Stefano Puliatti, Salvatore Micali, Luigi Schips

Review – Clinical Oncology

Mistletoe in oncological treatment: a systematic review

M. Freuding, C. Keinki, S. Kutschan, O. Micke, J. Buentzel, Jutta Huebner

Nephrectomy Original Article – Clinical Oncology

Preoperative controlling nutritional status (CONUT) score as a novel immune-nutritional predictor of survival in non-metastatic clear cell renal cell carcinoma of ≤ 7 cm on preoperative imaging

Ahmed Elghiaty, Jongchan Kim, Won Sik Jang, Jee Soo Park, Ji Eun Heo, Koon Ho Rha, Young Deuk Choi, Won Sik Ham

Gastric Cancer Original Article – Clinical Oncology

Prognostic role of glycolysis for cancer outcome: evidence from 86 studies

Min Yu, Shengying Chen, Weifeng Hong, Yujun Gu, Bowen Huang, Ye Lin, Yu Zhou, Haosheng Jin, Yanying Deng, Lei Tu, Baohua Hou, Zhixiang Jian

Open Access Acute Lymphoblastic Leukemia Original Article – Clinical Oncology

Reduced vs. standard dose native E. coli-asparaginase therapy in childhood acute lymphoblastic leukemia: long-term results of the randomized trial Moscow–Berlin 2002

Alexander Karachunskiy, Gesche Tallen, Julia Roumiantseva, Svetlana Lagoiko, Almira Chervova, Arend von Stackelberg, Olga Aleinikova, Oleg Bydanov, Lyudmila Bajdun, Tatiana Nasedkina, Natalia Korepanova, Sergei Kuznetsov, Galina Novichkova, Marina Goroshkova, Dmitry Litvinov, Natalia Myakova, Natalia Ponomareva, Evgeniya Inyushkina, Konstantin Kondratchik, Julia Abugova, Larisa Fechina, Oleg Arakaev, Alexander Karelin, Vladimir Lebedev, Natalia Judina, Gusel Scharapova, Irina Spichak, Anastasia Shamardina, Olga Ryskal, Alexander Shapochnik, Alexander Rumjanzew, Joachim Boos, Günter Henze

NSCLC Original Article – Clinical Oncology

Does FDG PET/CT have a role in determining adjuvant chemotherapy in surgical margin-negative stage IA non-small cell lung cancer patients?

Hye Lim Park, Ie Ryung Yoo, Sun Ha Boo, Sonya Youngju Park, Jae Kil Park, Sook Whan Sung, Seok Whan Moon

NSCLC Original Article – Clinical Oncology

Aggregate analysis based on TCGA: TTN missense mutation correlates with favorable prognosis in lung squamous cell carcinoma

Xingyu Cheng, Han Yin, Juan Fu, Chunya Chen, Jianhong An, Jiexia Guan, Rong Duan, Hengming Li, Hong Shen

Glioblastoma Original Article – Clinical Oncology

Regorafenib in patients with recurrent high-grade astrocytoma

Sied Kebir, Laurel Rauschenbach, Alexander Radbruch, Lazaros Lazaridis, Teresa Schmidt, Ann-Kathrin Stoppek, Daniela Pierscianek, Martin Stuschke, Michael Forsting, Ulrich Sure, Kathy Keyvani, Christoph Kleinschnitz, Björn Scheffler, Martin Glas

Rectal Cancer Original Article – Clinical Oncology

Prognostic relevance of programmed cell death-ligand 1 expression and CD8+ TILs in rectal cancer patients before and after neoadjuvant chemoradiotherapy

Tsung-Wei Chen, Kevin Chih-Yang Huang, Shu-Fen Chiang, William Tzu-Liang Chen, Tao-Wei Ke, K. S. Clifford Chao

Metastasis Original Article – Clinical Oncology

Lymph node ratio predictive of recurrence, distant metastasis, and survival in submandibular gland carcinoma patients

Won Ki Cho, Jong-Lyel Roh, Kyung-Ja Cho, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim

Ovarian Cancer Original Article – Clinical Oncology

Vascular endothelial growth factor receptor 2 (VEGFR2) correlates with long-term survival in patients with advanced high-grade serous ovarian cancer (HGSOC): a study from the Tumor Bank Ovarian Cancer (TOC) Consortium

Jun Guan, Silvia Darb-Esfahani, Rolf Richter, Eliane T. Taube, Ilary Ruscito, Sven Mahner, Linn Woelber, Katharina Prieske, Nicole Concin, Ignace Vergote, Els Van Nieuwenhuysen, Patriciu Achimas-Cadariu, Joanna Glajzer, Hannah Woopen, Mandy Stanske, Hagen Kulbe, Carsten Denkert, Jalid Sehouli, Elena Ioana Braicu

Open Access Rectal Cancer Original Article – Clinical Oncology

Neoadjuvant chemoradiotherapy delivered with helical tomotherapy under daily image guidance for rectal cancer patients: efficacy and safety in a large, multi-institutional series

Berardino De Bari, Alessandra Franzetti-Pellanda, Asma Saidi, Maira Biggiogero, Dieter Hahnloser, Michael Montemurro, Jean Bourhis, Michele Zeverino, Mahmut Ozsahin

Gastric Cancer Retraction Note

Retraction Note to: SOX2 oncogenes amplified and operate to activate AKT signalling in gastric cancer and predict immunotherapy responsiveness

Yajun Tian, Xin Jia, Shengxiang Wang, Yongsheng Li, Peng Zhao, Da Cai, Zequan Zhou, Junmin Wang, Yi Luo, Maosheng Dong

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.