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Breast Cancer

Reassuring results for ART use in BRCA breast cancer survivors

The use of assisted reproductive technology to conceive after breast cancer in young BRCA1/2 carriers does not appear to worsen disease-free survival or pregnancy outcomes.

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Editor's Choice

Do PARP inhibitors have a role in the neoadjuvant setting?

Learn about the rationale for using PARP inhibitors in the neoadjuvant treatment of various cancers with homologous recombination repair deficiency, as well as the ongoing clinical trials and future directions.

Half-dose apixaban for cancer patients at risk for recurrent VTE

Patients requiring extended thromboprophylaxis after a first episode of cancer-related venous thromboembolism can be given a low dose of the factor X inhibitor apixaban.

Acromegaly and cancer

The incidence of secondary neoplasia in patients with acromegaly has increased in recent years. What are the risk factors for cancer in these patients, which cancers are most common, and how should screening be approached?

Hand cooling or compression nearly halves CIPN risk

Hand cooling and compression each significantly reduce the risk for high-grade chemotherapy-induced peripheral neuropathy in patients receiving treatment for breast cancer.

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Women’s health knowledge hub

Elevate your patient care with our comprehensive, evidence-based medical education on women's health. Designed to help you provide exceptional care for your female patients at every stage of life, we provide expert insights into topics such as reproductive health, menopause, breast cancer and sex-specific health risks and precision medicine.

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SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
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Video

Case Studies

Synchronous breast cancer and pleural mesothelioma

A woman who underwent mastectomy and chemotherapy for breast cancer subsequently developed chest pain and dyspnea. Would you have considered pleural mesothelioma as the cause?

A rare, late side effect of radiotherapy

A woman developed sudden painless ecchymosis (bruising) of her breast, which was thought to be related to the radiotherapy she received for early-stage breast cancer a year and a half earlier.

Breast metastases in a male patient with nasopharyngeal carcinoma

Nasopharyngeal carcinoma is known for its high potential to metastasize, but breast metastasis is rare. The authors describe the first case of synchronous breast metastases in a male patient.

At a glance: The DESTINY-Breast trials

The antibody–drug conjugate trastuzumab deruxtecan is being investigated in the DESTINY-Breast trials for the treatment of breast cancer.

Developed by: Springer Medicine
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Current Reviews

Male Breast Cancer: Clinicopathological Characteristics of the Patients Treated in a Tertiary Care Centre in Northeast India

Male breast cancer is a rare disease and accounts for ∼1% of all cancers in men. Men often present in an advanced stage of the disease. This is a case series analysis. The objective was to look for tumor characteristics, histological subtypes, and …

Therapy of early breast cancer: current status and perspectives

Medical advancements in breast cancer are truly remarkable. Especially in recent years, numerous new therapeutics have been approved and surgical strategies have been de-escalated for specific patient groups. In the therapeutic setting, CDK4/6 …

Cardio-Oncology and Breast Cancer Therapies

Assessing cardiac risk prior to initiating breast cancer treatment, monitoring cardiac function during treatment, and implementing appropriate follow-up strategies are essential components of managing cardiotoxicity in breast cancer patients. A …

Oncological needs in transgender patients

Transgender people encounter unique health disparities in oncology. They face substantial barriers in accessing healthcare that are exaggerated by bias/discrimination from healthcare professionals and systems, and socio-economic marginalisation.

Episode 15: Breastfeeding after breast cancer

POSITIVEly reassuring results from a clinical trial

The POSITIVE trial previously showed that women with breast cancer can safely interrupt endocrine therapy in order to become pregnant. But what about breastfeeding - is that possible and safe for the mother and baby?

Women can take heart from the latest findings, says Dr. Cristina Saura, as she takes us through these important clinical updates.

Dr. Cristina Saura
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Podcast

Further Reading

Association of statin use on survival outcomes of patients with early-stage HER2-positive breast cancer in the APHINITY trial

About 15%−20% of all breast cancers (BC) show overexpression/amplification of the human epidermal growth factor receptor 2 (HER2). In the absence of specific anti-HER2 treatments, HER2-positive (HER2+) BC is an aggressive BC subtype with worse …

Impact of Immediate Unilateral Breast Reconstruction with Abdominal Flaps on Quality of Life: A Single-Center Prospective Interventional Study in Egypt

A woman’s breasts are an essential part of her body image, and a breast cancer diagnosis can significantly impact that image, potentially leading to lifelong struggles [ 1 , 2 ]. Breast cancer constitutes a significant global health challenge, with …

Differential Effects of Endocrine Therapy Type on Quality of Life in Older (≥70 Years) Women with Early-Stage Breast Cancer

The REQUITE group study ( www.requite.eu ) is a multicenter prospective study conducted across 26 countries in Europe and North America. 23 The study was designed to identify and validate predictive genetic markers that predict risk of late …

Male Breast Cancer: Clinicopathological Characteristics of the Patients Treated in a Tertiary Care Centre in Northeast India

Male breast cancer is a rare disease and accounts for ∼1% of all cancers in men. Men often present in an advanced stage of the disease. This is a case series analysis. The objective was to look for tumor characteristics, histological subtypes, and …