01-04-2021 | Giant Cell Arteritis | Review Article
Cognitive impairment in elderly patients with rheumatic disease and the effect of disease-modifying anti-rheumatic drugs
Published in: Clinical Rheumatology | Issue 4/2021
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Key points • Patients with chronic rheumatic conditions are beginning to live longer, adding to the elderly population. • Patients with chronic rheumatologic disease are at increased risk of cognitive impairment compared to the general population. • Recent development of biologic (i.e., TNF, IL-1, IL-6) and targeted drugs (i.e., Janus kinase inhibitors) have led to better control of disease activity. • Current evidence suggests that TNF inhibitors may have beneficial effects on cognitive function. However, evidence on newer biologic and targeted therapies is limited. |