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Diabetology

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Suboptimal CKD screening in people with type 2 diabetes

08-07-2024 Diabetic Nephropathy News

As many as three-quarters of US adults with type 2 diabetes are not being routinely screened for indicators of chronic kidney disease.

Fixed-ratio combinations for glycemic control

Open Access Diabetes Therapy Expert Opinion

How might fixed-ratio combinations of basal insulins and GLP-1 receptor agonists be used to optimize treatment of type 2 diabetes? Find out more in this expert opinion paper.

Routine stress testing provides no protection in ACS after PCI

Routine cardiac stress testing is no better than standard care in patients with acute coronary syndrome following successful PCI.

Cardiometabolic risks in cancer survivorship

Open Access Circulatory Disease Review

Patients can face many cardiometabolic challenges after cancer. Understand the impact of demographic variables, specific cancer types, and treatment modalities on cardiometabolic health in cancer survivors.

Managing type 2 diabetes and lower extremity PAD

Open Access Type 2 Diabetes Review

GLP-1 receptor agonists and SGLT2 inhibitors have demonstrated cardiovascular benefits, but where do they fit in the management of individuals who have type 2 diabetes and peripheral artery disease?

Survodutide shows promise for treating MASH

Survodutide beats placebo at improving metabolic dysfunction–associated steatohepatitis without worsening fibrosis.

Tirzepatide shows promise for obstructive sleep apnea

Tirzepatide may reduce sleep apnea severity in people with moderate-to-severe obstructive sleep apnea and obesity, show data from the SURMOUNT-OSA phase 3 trials.

Abnormal glycated hemoglobin level in a patient with diabetes

Open Access Type 2 Diabetes Case Study

HbA1c levels that don’t match the clinical picture need further investigation. Other factors, such as Hb variants, can interfere with the HbA1c measurement and make glycemic control difficult to achieve.

Hyperglycemic crises in adults with diabetes: a consensus report

Open Access Hyperglycemia Review

Update on the epidemiology, pathophysiology, and clinical presentation of DKA and HHS in adults with diabetes, with recommendations for diagnosis, treatment, and prevention.

Diabetes technology in the hospital

Diabetes Review

The use of diabetes technology in the inpatient setting is still limited, but integrating smarter glucose monitoring and insulin delivery devices into this environment could reduce diabetes-related morbidity and mortality.

Tirzepatide shows promise for MASH

Tirzepatide may be a suitable treatment for metabolic dysfunction-associated steatohepatitis with moderate or severe fibrosis, show data from the phase 2 SYNERGY-NASH trial.

Metformin not linked to poor pregnancy outcomes

19-06-2024 Diabetes and Pregnancy News

Adding insulin to metformin in early pregnancy does not increase the risk for stillbirth or congenital malformities versus switching to insulin monotherapy in women with type 2 diabetes.

EASL–EASD–EASO CPGs on the management of MASLD: executive summary

Discover the recommendations and statements in the new multi-society clinical practice guidelines on the diagnosis, treatment, and follow-up of individuals with metabolic dysfunction-associated steatotic liver disease.

A challenging case of CAP

Open Access Community-Acquired Pneumonia Case Study

A woman presenting with community-acquired pneumonia developed several serious complications, likely due to co-existence of poorly controlled diabetes and a late diagnosis of thyroid cancer.

Diabesity, stress, and cancer risk

Open Access Diabetes Review

Explore the relationship between emotional wellbeing, metabolic health, and the risk of developing cancer. Learn how stress may worsen the increased cancer risk in people with diabetes, obesity, or both.

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

Cardiorenal benefits of semaglutide in type 2 diabetes with CKD

05-06-2024 Type 2 Diabetes News

Semaglutide has renal and cardioprotective effects in people with type 2 diabetes and chronic kidney disease who are at high risk for complications. 

Measuring ketone bodies

Measurement of ketones is encouraged to aid the diagnosis and assessment of diabetic ketoacidosis, but which method should be used: urine analysis, blood testing, or measurement of breath acetone?

Near-lifelong benefits of early intensive glycemic control

30-05-2024 Type 2 Diabetes News

The benefits of early intensive glycemic control in people with newly diagnosed type 2 diabetes have persisted for up to 24 years since the UKPDS trial ended.

DPP4 inhibitors a cause of IgG4-related kidney disease?

A man with type 2 diabetes and IgG4-related kidney disease developed bullous pemphigoid. DPP4 inhibitor treatment, which also correlated with changes in renal function, was discontinued.