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Diabetologia

Issue 3/2020

Content (21 Articles)

In Memoriam

Lelio Orci 1937–2019

Roberto Montesano, Alain Perrelet

Open Access Insulins Review

Sex differences in metabolic regulation and diabetes susceptibility

Blandine Tramunt, Sarra Smati, Naia Grandgeorge, Françoise Lenfant, Jean-François Arnal, Alexandra Montagner, Pierre Gourdy

Insulins Review

Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes

Ivy C. Mason, Jingyi Qian, Gail K. Adler, Frank A. J. L. Scheer

Open Access Semaglutide Article

Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trial

Rory J. McCrimmon, Andrei-Mircea Catarig, Juan P. Frias, Nanna L. Lausvig, Carel W. le Roux, Desirée Thielke, Ildiko Lingvay

Open Access Prediabetes Article

A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to prevent type 2 diabetes in India and the UK: a randomised controlled trial

Arun Nanditha, Hazel Thomson, Priscilla Susairaj, Weerachai Srivanichakorn, Nick Oliver, Ian F. Godsland, Azeem Majeed, Ara Darzi, Krishnamoorthy Satheesh, Mary Simon, Arun Raghavan, Ramachandran Vinitha, Chamukuttan Snehalatha, Kate Westgate, Soren Brage, Stephen J. Sharp, Nicholas J. Wareham, Desmond G. Johnston, Ambady Ramachandran

Obesity Article

Cord blood metabolic markers are strong mediators of the effect of maternal adiposity on fetal growth in pregnancies across the glucose tolerance spectrum: the PANDORA study

I-Lynn Lee, Elizabeth L. M. Barr, Danielle Longmore, Federica Barzi, Alex D. H. Brown, Christine Connors, Jacqueline A. Boyle, Marie Kirkwood, Vanya Hampton, Michael Lynch, Zhong X. Lu, Kerin O’Dea, Jeremy Oats, H. David McIntyre, Paul Zimmet, Jonathan E. Shaw, Louise J. Maple-Brown

Open Access Premature Birth Article

Preterm birth and risk of type 1 and type 2 diabetes: a national cohort study

Casey Crump, Jan Sundquist, Kristina Sundquist

Obesity Article

A comparison of obesity indices in relation to mortality in type 2 diabetes: the Fremantle Diabetes Study

Joel Tate, Matthew Knuiman, Wendy A. Davis, Timothy M. E. Davis, David G. Bruce

Open Access Type 2 Diabetes Article

Association of moderate and vigorous physical activity with incidence of type 2 diabetes and subsequent mortality: 27 year follow-up of the Whitehall II study

Manasa S. Yerramalla, Aurore Fayosse, Aline Dugravot, Adam G. Tabak, Mika Kivimäki, Archana Singh-Manoux, Séverine Sabia

Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates

Marika Bogdani, Cate Speake, Mathew J. Dufort, Pamela Y. Johnson, Megan J. Larmore, Anthony J. Day, Thomas N. Wight, Åke Lernmark, Carla J. Greenbaum

Insulins Article

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice

Yi-Chun Chen, Richard E. Mains, Betty A. Eipper, Brad G. Hoffman, Traci A. Czyzyk, John E. Pintar, C. Bruce Verchere

Insulins Article

Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway

Jun Shirakawa, Kazuki Tajima, Tomoko Okuyama, Mayu Kyohara, Yu Togashi, Dario F. De Jesus, Giorgio Basile, Tatsuya Kin, A. M. James Shapiro, Rohit N. Kulkarni, Yasuo Terauchi

The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening

Laura M. Jacobsen, Laura Bocchino, Carmella Evans-Molina, Linda DiMeglio, Robin Goland, Darrell M. Wilson, Mark A. Atkinson, Tandy Aye, William E. Russell, John M. Wentworth, David Boulware, Susan Geyer, Jay M. Sosenko

Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial

Pieter F. de Groot, Tatjana Nikolic, Sultan Imangaliyev, Siroon Bekkering, Gaby Duinkerken, Fleur M. Keij, Hilde Herrema, Maaike Winkelmeijer, Jeffrey Kroon, Evgeni Levin, Barbara Hutten, Elles M. Kemper, Suat Simsek, Johannes H. M. Levels, Flora A. van Hoorn, Renuka Bindraban, Alicia Berkvens, Geesje M. Dallinga-Thie, Mark Davids, Frits Holleman, Joost B. L. Hoekstra, Erik S. G. Stroes, Mihai Netea, Daniël H. van Raalte, Bart O. Roep, Max Nieuwdorp

A single bout of resistance exercise improves postprandial lipid metabolism in overweight/obese men with prediabetes

Adam J. Bittel, Daniel C. Bittel, Bettina Mittendorfer, Bruce W. Patterson, Adewole L. Okunade, Jun Yoshino, Lane C. Porter, Nada A. Abumrad, Dominic N. Reeds, W. Todd Cade

Open Access Type 2 Diabetes Article

Type 2 diabetes does not account for ethnic differences in exercise capacity or skeletal muscle function in older adults

Siana Jones, Therese Tillin, Suzanne Williams, Sophie V. Eastwood, Alun D. Hughes, Nishi Chaturvedi

Open Access Albuminuria Article

Predicting renal disease progression in a large contemporary cohort with type 1 diabetes mellitus

Marco Colombo, Stuart J. McGurnaghan, Samira Bell, Finlay MacKenzie, Alan W. Patrick, John R. Petrie, John A. McKnight, Sandra MacRury, Jamie Traynor, Wendy Metcalfe, Paul M. McKeigue, Helen M. Colhoun

Incidence and relative risk of renal replacement therapy in people with and without diabetes between 2002 and 2016 in a German region

Maria Narres, Heiner Claessen, Tatjana Kvitkina, Michael Koch, Lars Christian Rump, Thomas Weinreich, Andrea Icks

Open Access Article

Geospatial mapping and data linkage uncovers variability in outcomes of foot disease according to multiple deprivation: a population cohort study of people with diabetes

Joanne E. Hurst, Ruth Barn, Lesley Gibson, Hamish Innes, Sicco A. Bus, Brian Kennon, David Wylie, James Woodburn

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.