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Current Neurology and Neuroscience Reports

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01-03-2022 | Central Nervous System Trauma | Neurotrauma (D. Sandsmark, Section Editor)

Neuromodulation Treatments for Mild Traumatic Brain Injury and Post-concussive Symptoms

Authors: Adriano Mollica, Rachel Greben, Chika Oriuwa, Shan H. Siddiqi, Matthew J. Burke

Published in: Current Neurology and Neuroscience Reports | Issue 3/2022

Abstract

Purpose of Review

Mild traumatic brain injury (mTBI) can result in prolonged post-concussive symptoms (e.g., depression, headaches, cognitive impairment) that are debilitating and difficult to treat. This article reviews recent research on neuromodulation for mTBI.

Recent Findings

Transcranial magnetic stimulation (TMS) is the most studied neuromodulation approach for mTBI (four studies for depression, four for headache, one for cognitive impairment, and two for global post-concussive symptoms) with promising results for post-concussive depression and headache. Transcranial direct current stimulation (tDCS) has also been evaluated (one study for post-traumatic headache, and three for cognitive impairment), with more mixed results overall.

Summary

TMS appears to be a potentially promising neuromodulation treatment strategy for post-concussive symptoms; however, integration into clinical practice will require larger sham-controlled randomized trials with longer and more consistent follow-up periods. Future studies should also explore new stimulation protocols, personalized approaches, and the role of placebo effects.

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Title: Neuromodulation Treatments for Mild Traumatic Brain Injury and Post-concussive Symptoms
Authors: Adriano Mollica
Rachel Greben
Chika Oriuwa
Shan H. Siddiqi
Matthew J. Burke
Publication date: 01-03-2022
Publisher: Springer US
Keywords: Central Nervous System Trauma
Mood Disorders
Transcranial Magnetic Stimulation
Affective Disorder
Traumatic Brain Injuries
Nerve Stimulation
Headache
Transcranial Magnetic Stimulation
Published in: Current Neurology and Neuroscience Reports / Issue 3/2022
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI: https://doi.org/10.1007/s11910-022-01183-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Neuromodulation Treatments for Mild Traumatic Brain Injury and Post-concussive Symptoms

Abstract

Purpose of Review

Recent Findings

Summary

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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