Issue 1/2023
Content (27 Articles)
Arginase-1 inhibition reduces migration ability and metastatic colonization of colon cancer cells
Xiangdong Wang, Huihui Xiang, Yujiro Toyoshima, Weidong Shen, Shunsuke Shichi, Hiroki Nakamoto, Saori Kimura, Ko Sugiyama, Shigenori Homma, Yohei Miyagi, Akinobu Taketomi, Hidemitsu Kitamura
Metabolic profiling reveals metabolic features of consolidation therapy in pediatric acute lymphoblastic leukemia
Jinqiu Fu, Aijun Zhang, Qinqin Liu, Dong Li, Xiaoming Wang, Libo Si
Tamoxifen induces radioresistance through NRF2-mediated metabolic reprogramming in breast cancer
F. V. Naumann, F. C. G. J. Sweep, G. J. Adema, W. J. M. Peeters, J. W. M. Martens, J. Bussink, P. N. Span
Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells
Mika B. Jekabsons, Mollie Merrell, Anna G. Skubiz, Noah Thornton, Sandra Milasta, Douglas Green, Taosheng Chen, Yan-Hong Wang, Bharathi Avula, Ikhlas A. Khan, Yu-Dong Zhou
Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia
Martijn G. S. Rutten, Yu Lei, Joanne H. Hoogerland, Vincent W. Bloks, Hong Yang, Trijnie Bos, Kishore A. Krishnamurthy, Aycha Bleeker, Mirjam H. Koster, Rachel E. Thomas, Justina C. Wolters, Hilda van den Bos, Gilles Mithieux, Fabienne Rajas, Adil Mardinoglu, Diana C. J. Spierings, Alain de Bruin, Bart van de Sluis, Maaike H. Oosterveer
Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with advanced, inoperable pancreatic adenocarcinoma: a phase 1b observational study
Lauren K. Park, Kian-Huat Lim, Jonas Volkman, Mina Abdiannia, Hannah Johnston, Zack Nigogosyan, Marilyn J. Siegel, Janet B. McGill, Alexis M. McKee, Maamoun Salam, Rong M. Zhang, Da Ma, Karteek Popuri, Vincent Tze Yang Chow, Mirza Faisal Beg, William G. Hawkins, Linda R. Peterson, Joseph E. Ippolito
Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer
Chunjing Wu, Sydney A. Spector, George Theodoropoulos, Dan J. M. Nguyen, Emily Y. Kim, Ashley Garcia, Niramol Savaraj, Diane C. Lim, Ankita Paul, Lynn G. Feun, Michael Bickerdike, Medhi Wangpaichitr
Obesity and breast cancer prognosis: pre-diagnostic anthropometric measures in relation to patient, tumor, and treatment characteristics
Sixten Harborg, Maria Feldt, Deirdre Cronin-Fenton, Marie Klintman, Susanne O. Dalton, Ann H. Rosendahl, Signe Borgquist
BMP4 upregulates glycogen synthesis through the SMAD/SLC2A1 (GLUT1) signaling axis in hepatocellular carcinoma (HCC) cells
Jiamin Zhong, Luyao Tian, Yannian Gou, Piao Zhao, Xiangyu Dong, Meichun Guo, Guozhi Zhao, Aohua Li, Ailing Hao, Tong-Chuan He, Jiaming Fan
Long non-coding RNA CCHE1 modulates LDHA-mediated glycolysis and confers chemoresistance to melanoma cells
Zhi Ding, Junyi Yang, Baojin Wu, Yingzhi Wu, Fanli Guo
Restoring gluconeogenesis by TEF inhibited proliferation and promoted apoptosis and immune surveillance in kidney renal clear cell carcinoma
Wenyuan Zhuang, Xiaokai Shi, Shenglin Gao, Xihu Qin
Magnetospirillum magneticum triggers apoptotic pathways in human breast cancer cells
Stefano Menghini, Matej Vizovisek, Jonathas Enders, Simone Schuerle
Comparative polar and lipid plasma metabolomics differentiate KSHV infection and disease states
Sara R. Privatt, Camila Pereira Braga, Alicia Johnson, Salum J. Lidenge, Luke Berry, John R. Ngowi, Owen Ngalamika, Andrew G. Chapple, Julius Mwaiselage, Charles Wood, John T. West, Jiri Adamec
Positron emission tomography imaging of the sodium iodide symporter senses real-time energy stress in vivo
Piotr Dzien, Agata Mackintosh, Gaurav Malviya, Emma Johnson, Dmitry Soloviev, Gavin Brown, Alejandro Huerta Uribe, Colin Nixon, Scott K. Lyons, Oliver Maddocks, Karen Blyth, David Y. Lewis
Cholesterol reprograms glucose and lipid metabolism to promote proliferation in colon cancer cells
Shyamananda Singh Mayengbam, Abhijeet Singh, Himanshi Yaduvanshi, Firoz Khan Bhati, Bhavana Deshmukh, Dipti Athavale, Pranay L. Ramteke, Manoj Kumar Bhat
Identification of predictive biomarkers for endometrial cancer diagnosis and treatment response monitoring using plasma metabolome profiling
Eiji Hishinuma, Muneaki Shimada, Naomi Matsukawa, Yoshiko Shima, Bin Li, Ikuko N. Motoike, Yusuke Shibuya, Tatsuya Hagihara, Shogo Shigeta, Hideki Tokunaga, Daisuke Saigusa, Kengo Kinoshita, Seizo Koshiba, Nobuo Yaegashi
Untargeted plasma metabolomics and risk of colorectal cancer—an analysis nested within a large-scale prospective cohort
Linda Vidman, Rui Zheng, Stina Bodén, Anton Ribbenstedt, Marc J. Gunter, Richard Palmqvist, Sophia Harlid, Carl Brunius, Bethany Van Guelpen
Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition
Amy K. Holt, Arafath K. Najumudeen, Tracey J. Collard, Hao Li, Laura M. Millett, Ashley J. Hoskin, Danny N. Legge, Eleanor M. H. Mortensson, Dustin J. Flanagan, Nicholas Jones, Madhu Kollareddy, Penny Timms, Matthew D. Hitchings, James Cronin, Owen J. Sansom, Ann C. Williams, Emma E. Vincent
Correction: Cholesterol reprograms glucose and lipid metabolism to promote proliferation in colon cancer cells
Shyamananda Singh Mayengbam, Abhijeet Singh, Himanshi Yaduvanshi, Firoz Khan Bhati, Bhavana Deshmukh, Dipti Athavale, Pranay L. Ramteke, Manoj Kumar Bhat
ATM inhibition blocks glucose metabolism and amplifies the sensitivity of resistant lung cancer cell lines to oncogene driver inhibitors
Cristina Terlizzi, Viviana De Rosa, Francesca Iommelli, Antonio Pezone, Giovanna G. Altobelli, Maurizio Maddalena, Jelena Dimitrov, Caterina De Rosa, Carminia Maria Della Corte, Vittorio Enrico Avvedimento, Silvana Del Vecchio
The effects of chemotherapy on resting energy expenditure, body composition, and cancer-related fatigue in women with breast cancer: a prospective cohort study
Timia Van Soom, Wiebren Tjalma, Konstantinos Papadimitriou, Nick Gebruers, Eric van Breda
Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages
Shelby N. Bess, Matthew J. Igoe, Abby C. Denison, Timothy J. Muldoon
Metabolic changes preceding bladder cancer occurrence among Korean men: a nested case-control study from the KCPS-II cohort
Youngmin Han, Unchong Kim, Keum Ji Jung, Ji-Young Lee, Kwangbae Lee, Sang Yop Shin, Heejin Kimm, Sun Ha Jee
The classification of obesity based on metabolic status redefines the readmission of non-Hodgkin’s lymphoma—an observational study
Hang Dong, Honglin Guo, Jing Du, Yiping Cheng, Dawei Wang, Junming Han, Zinuo Yuan, Zhenyu Yao, Ran An, Xiaoqin Wu, Kyle L. Poulsen, Zhixiang Wang, Shanshan Shao, Xiude Fan, Zhen Wang, Jiajun Zhao
A HIF-1α inhibitor combined with palmitic acid and L-carnitine treatment can prevent the fat metabolic reprogramming under hypoxia and induce apoptosis in hepatocellular carcinoma cells
Shohei Matsufuji, Yoshihiko Kitajima, Kazuki Higure, Naoya Kimura, Sachiko Maeda, Kohei Yamada, Kotaro Ito, Tomokazu Tanaka, Keita Kai, Hirokazu Noshiro
STEAP4 inhibits cisplatin-induced chemotherapy resistance through suppressing PI3K/AKT in hepatocellular carcinoma
Binhui Xie, Baiyin Zhong, Zhenxian Zhao, Jie Hu, Jianqiong Yang, Yuankang Xie, Jianhong Zhang, Jianting Long, Xuewei Yang, Heping Li
A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC
Huihua Yang, Dahong Chen, Yafei Wu, Heming Zhou, Wenjing Diao, Gaolin Liu, Qin Li