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01-02-2017 | Editorial

What do we know? What do we need to know?

Authors: Milena J. Henzlova, MD, W. Lane Duvall, MD

Published in: Journal of Nuclear Cardiology | Issue 1/2017

Excerpt

Nuclear cardiology experienced unprecedented growth in the 1980-1990’s after the introduction of SPECT technology, development of Tc-99m-based tracers,1 and utilization of coronary vasodilators for pharmacologic stress.2-4 During the late part of the last century, nuclear cardiology became a dominant physiologic and noninvasive method for the diagnosis, risk stratification, and prognostication of epicardial coronary artery disease (CAD). However, the arrival of competing diagnostic modalities used for similar indications, such as coronary CT angiography and stress echocardiography, unmasked weaknesses of the radionuclide methods, particularly the length of the procedure, relatively high radiation doses for a diagnostic test,5,6 and possible underestimation of the extent of the disease.7 …

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Lima R, Peclat T, Soares T, Ferreira C, Souza, AC, Camargo G. Comparison of the prognostic value of myocardial perfusion imaging using a CZT-SPECT camera with a conventional anger camera. J Nucl Cardiol 2016. doi:10.1007/s12350-016-0618-9.PubMed

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Duvall WL, Croft LB, Ginsberg ES, Einstein AJ, Guma KA, George T, et al. Reduced isotope dose and imaging time with a high-efficiency CZT SPECT camera. J Nucl Cardiol 2011;18:847-57.CrossRefPubMed

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Chowdhury FU, Vaidyanathan S, Bould M, Marsh J, Trickett C, Dodds K, et al. Rapid-acquisition myocardial perfusion scintigraphy (MPS) on a novel gamma camera using multipinhole collimation and miniaturized cadmium-zinc-telluride (CZT) detectors: Prognostic value and diagnostic accuracy in a ‘real-world’ nuclear cardiology service. Eur Heart J Cardiovasc Imaging 2014;15:275-83.CrossRefPubMed

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Oldan JD, Shaw LK, Hofmann P, Phelan M, Nelson J, Pagnanelli R, et al. Prognostic value of the cadmium-zinc-telluride camera: A comparison with a conventional (Anger) camera. J Nucl Cardiol 2015. doi:10.1007/s12350-015-0181-9.PubMedCentral

18.

Einstein AJ, Johnson LL, DeLuca AJ, Kontak AC, Groves DW, Stant J, et al. Radiation dose and prognosis of ultra-low-dose stress-first myocardial perfusion SPECT in patients with chest pain using a high-efficiency camera. J Nucl Med 2015;56:545-51.CrossRefPubMed

19.

Yokota S, Mouden M, Ottervanger JP, Engbers E, Knollema S, Timmer JR, et al. Prognostic value of normal stress-only myocardial perfusion imaging: a comparison between conventional and CZT-based SPECT. Eur J Nucl Med Mol Imaging 2016;43:296-301.CrossRefPubMed

20.

Gimelli A, Bottai M, Giorgetti A, Genovesi D, Filidei E, Marzullo P. Evaluation of ischaemia in obese patients: feasibility and accuracy of a low-dose protocol with a cadmium-zinc telluride camera. Eur J Nucl Med Mol Imaging 2012;39:1254-61.CrossRefPubMed

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De Lorenzo A, Peclat T, Amaral AC, Lima RS. Prognostic evaluation in obese patients using a dedicated multipinhole cadmium-zinc telluride SPECT camera. Int J Cardiovasc Imaging 2016;32:355-61.CrossRefPubMed

22.

Nakazato R, Slomka PJ, Fish M, Schwartz RG, Hayes SW, Thomson LE, et al. Quantitative high-efficiency cadmium-zinc-telluride SPECT with dedicated parallel-hole collimation system in obese patients: results of a multi-center study. J Nucl Cardiol 2015;22:266-75.CrossRefPubMed

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Kobayashi M, Matsunari I, Nishi K, Mizutani A, Miyazaki Y, Ogai K, et al. Simultaneous acquisition of (99m)Tc- and (123)I-labeled radiotracers using a preclinical SPECT scanner with CZT detectors. Ann Nucl Med 2016;30:263-71.CrossRefPubMed

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Nkoulou R, Fuchs TA, Pazhenkottil AP, Kuest SM, Ghadri JR, Stehli J, et al. Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium-Zinc-Telluride Detectors Using 99mTc-Tetrofosmin: Head to Head Comparison with 13N-Ammonia PET. J Nucl Med 2016. doi:10.2967/jnumed.115.165498.PubMed

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Title: What do we know? What do we need to know?
Authors: Milena J. Henzlova, MD
W. Lane Duvall, MD
Publication date: 01-02-2017
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 1/2017
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-016-0640-y

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