We here present a case of cardiac fibroma mimicking a malignant tumor due to the 18F-fluorodeoxyglucose (FDG) high accumulation. A 23-year-old woman was found asymptomatic bradycardia by a health checkup. Echocardiography detected the wall thickening in the basal septal portion of the left ventricle (LV) (supplementary movies). As cardiac tumor was suspected, further evaluations including FDG positron emission tomography (PET)/computed tomography (CT) and enhanced magnetic resonance imaging (MRI) were performed. To suppress physiological myocardial uptake, this patient fasted for 18 h with unfractionated heparin (50 IU·kg−1) i.v. injected 15 minutes prior to FDG administration.1 FDG PET/CT showed focal tracer accumulation in the entire mass (Figure 1A, B). Cardiac MRI showed iso-intense on T1-weighed image (T1WI) (Figure 1C), hypo-intense on T2-weighed image (T2WI) (Figure 1D), and hyper-intense on late gadolinium enhancement (LGE) (Figure 1E) in the mass.