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Acta Diabetologica
Published in: Acta Diabetologica 6/2019

01-06-2019 | Type 1 Diabetes | Short Communication

A marker of type VI collagen formation (PRO-C6) is associated with higher arterial stiffness in type 1 diabetes

Authors: Marie Frimodt-Møller, Tine W. Hansen, Daniel G. K. Rasmussen, Simone Theilade, Signe H. Nielsen, Morten A. Karsdal, Federica Genovese, Peter Rossing

Published in: Acta Diabetologica | Issue 6/2019

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Excerpt

Persons with type 1 diabetes (T1D) have increased risk of cardiovascular disease. Large artery stiffness is an important determinant of cardiovascular risk. Carotid–femoral pulse wave velocity (cfPWV) is considered the gold standard measure of arterial stiffness, and has been shown to be a strong predictor of mortality and cardiovascular outcome [1]. …
Literature
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Vlachopoulos C, Aznaouridis K, Stefanadis C (2010) Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 55(13):1318–1327CrossRef
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Lacolley P, Regnault V, Segers P, Laurent S (2017) Vascular smooth muscle cells and arterial stiffening: relevance in development, aging, and disease. Physiol Rev 97(4):1555–1617CrossRefPubMed
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4.
Rasmussen DGK, Hansen TW, von Scholten BJ et al (2018) Higher collagen VI formation is associated with all-cause mortality in patients with type 2 diabetes and microalbuminuria. Diabetes Care
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Theilade S, Lajer M, Persson F, Joergensen C, Rossing P (2013) Arterial stiffness is associated with cardiovascular, renal, retinal, and autonomic disease in type 1 diabetes. Diabetes Care 36(3):715–721CrossRefPubMedPubMedCentral
Metadata
Title
A marker of type VI collagen formation (PRO-C6) is associated with higher arterial stiffness in type 1 diabetes
Authors
Marie Frimodt-Møller
Tine W. Hansen
Daniel G. K. Rasmussen
Simone Theilade
Signe H. Nielsen
Morten A. Karsdal
Federica Genovese
Peter Rossing
Publication date
01-06-2019
Publisher
Springer Milan
Published in
Acta Diabetologica / Issue 6/2019
Print ISSN: 0940-5429
Electronic ISSN: 1432-5233
DOI
https://doi.org/10.1007/s00592-019-01306-9

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