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Published in: BMC Medical Imaging 1/2020

Open Access 01-12-2020 | Tuberculosis | Case report

False positive finding from malignancy-like lesions on FDG PET/CT: case report of tuberculosis patients

Authors: Febby Hutomo, Ryan Yudistiro, Ivana Dewi Mulyanto, Hendra Budiawan

Published in: BMC Medical Imaging | Issue 1/2020

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Abstract

Background

The F-18 fluorodeoxyglucose positron emission/computed tomography (FDG PET/CT) has become an established diagnostic imaging for malignancy. However, there are other diseases that can also be identified with FDG, some of them are infections such as tuberculosis.

Case presentation

In this case report, two patients showed multiple hypermetabolic tuberculosis lesions on FDG PET/CT, with one of the patients having history of malignancy. The objective of the present case report is to emphasize the need to use other differential diagnosis techniques for tuberculosis especially in tuberculosis-endemic countries when interpreting FDG PET/CT.

Conclusion

By analyzing diagnostic imaging alone, there is a high chance of misinterpreting asymptomatic tuberculosis patient as having malignancy. Therefore, there is need for correlation with clinical data as well as other imaging modalities and PET/CT with more specific tracer in order to differentiate malignancy from benign disease such as tuberculosis.
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Metadata
Title
False positive finding from malignancy-like lesions on FDG PET/CT: case report of tuberculosis patients
Authors
Febby Hutomo
Ryan Yudistiro
Ivana Dewi Mulyanto
Hendra Budiawan
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Medical Imaging / Issue 1/2020
Electronic ISSN: 1471-2342
DOI
https://doi.org/10.1186/s12880-020-00427-w

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