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Spinal Tumor 

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  1. Open Access 01-12-2024 | Spinal Tumor | OriginalPaper

    Perioperative complications of en bloc resection and anterior column reconstruction for thoracic and lumbar spinal tumors

    En bloc resection in the spine is a procedure of surgical oncology aimed at completely removing a tumoral mass, making it thoroughly surrounded by a continuous layer of healthy tissue, which is indicated for primary malignant tumors, aggressive …

  2. 07-05-2024 | Cancer Biomarker | Online First

    A case of a pineal parenchymal tumor of intermediate differentiation with bifocal lesions differentiated by negative placental alkaline phosphatase in the spinal fluid

    Placental alkaline phosphatase (PLAP) in the spinal fluid is helpful for the diagnosis of intracranial germinomas. Bifocal lesions involving the pineal and pituitary regions have also been reported as characteristic findings of intracranial …

  3. Open Access 01-12-2024 | Spinal Tumor | ReviewPaper

    Neurosurgical emergencies in spinal tumors: pathophysiology and clinical management

    Whether they are spinal metastases or primary spinal neoplasms, spinal tumors cause a myriad of complications given their critical location. Spinal tumors can be extradural, intradural extramedullary, or intramedullary, with extradural metastatic …

  4. Open Access 01-12-2024 | Spinal Tumor | OriginalPaper

    Nomogram for predicting postoperative pulmonary complications in spinal tumor patients

    Postoperative pulmonary complications (PPCs) have a significant impact on postoperative outcomes, and even mild PPCs are associated with a significant increase in early postoperative mortality, complications, intensive care unit (ICU) admissions …

  5. 07-02-2024 | Magnetic Resonance Imaging | OriginalPaper

    Development of a whole spinal MRI-based tumor burden scoring method in participants with multiple myeloma: a pilot study of prognostic significance

    The aim of the study was to develop a new whole spinal MRI-based tumor burden scoring method in participants with newly diagnosed multiple myeloma (MM) and to explore its prognostic significance. We prospectively recruited participants with newly …

  6. 07-02-2024 | Intramedullary Space-Occupying Lesion | OriginalPaper

    Intramedullary spinal cord tumors in pediatric patients presenting later with brain lesions: case series and systematic review of the literature

    Intramedullary spinal cord tumors (IMSCT) are an uncommon pathology in adults and children. While intramedullary tumors are more common in children than adults, they account for less than 30% of all spinal cord tumor cases in the pediatric …

  7. 19-08-2023 | Magnetic Resonance Imaging | OriginalPaper

    Comparison of machine learning algorithms for the classification of spinal cord tumor

    Spinal cord Tumor has been characterized as a heterogeneous disease consisting of many different subtypes. The early diagnosis and prognosis of a cancer type have become a necessity in cancer research, as it can facilitate the subsequent clinical …

  8. Open Access 01-06-2024 | Ependymoma | OriginalPaper

    Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation

    Ependymomas encompass multiple clinically relevant tumor types based on localization and molecular profiles. Tumors of the methylation class “spinal ependymoma” (SP-EPN) represent the most common intramedullary neoplasms in children and adults.

  9. 01-12-2024 | Spinal Tumor | ReviewPaper

    Fluorescence-guided resection of intradural spinal tumors: a systematic review and meta-analysis

    Intradural spinal tumors present significant challenges due to involvement of critical motor and sensory tracts. Achieving maximal resection while preserving functional tissue is therefore crucial. Fluorescence-guided surgery aims to improve …

  10. 06-12-2023 | Ependymoma | OriginalPaper

    RFX2 promotes tumor cell stemness through epigenetic regulation of PAF1 in spinal ependymoma

    Ependymal tumors are neuroepithelial neoplasms that frequently grow attached to ventricles or to the central canal of the spinal cord which principally occur in children, but may also disturb adults [ 1 ]. Patients with spinal ependymoma (SE) …

  11. Open Access 01-12-2023 | Intramedullary Space-Occupying Lesion | ReviewPaper

    The role of intraoperative neurophysiological monitoring in intramedullary spinal cord tumor surgery

    Intramedullary tumors are a class of central nervous system tumors with an incidence of 2 to 4%. As they are located very deep and frequently cause postoperative neurological complications, surgical resection is difficult. In recent years, many …

  12. 14-07-2023 | Spinal Tumor | OriginalPaper

    Postoperative survival after lumbar instrumented surgery for metastatic spinal tumors: a nationwide population-based cohort analysis

    Cancer is a devastating disease that can cause considerable morbidity to patients and is associated with the essential need for hospital resources. Vertebral column metastases are the most common sites of skeletal system metastasis [ 1 ]. As it …

  13. 14-11-2023 | Osteomalacia | Online First

    Spinal phosphaturic mesenchymal tumors: a rare etiology causing tumor-induced osteomalacia—a review of experience at a UK tertiary referral center and literature review

    Phosphaturic mesenchymal tumor (PMT) was initially described by Weidner and Santa Cruz in 1987 [ 1 ]. Spinal mesenchymal phosphaturic tumors, an extremely rare occurrence, have been the focus of limited clinical reports. While approximately 300 …

  14. Open Access 01-12-2023 | Ependymoma | OriginalPaper

    The frequency of various spinal cord tumors (SCTs) in surgically treated patients at Shiraz Shahid Chamran Hospital from 2012 to 2022

    Spinal cord tumors are relatively uncommon, accounting for 4–16% of all central nervous system (CNS) tumors [ 1 , 2 ]. In addition, the spine is one of the most frequent sites for bone metastases [ 3 ], which means around 70% of cancer patients …

  15. Open Access 01-12-2023 | Laminectomy | OriginalPaper

    Replantation of lamina spinous process ligament complex and miniature titanium plate shaping internal fixation in the treatment of tumors in the spinal canal

    Primary intraspinal tumors account for 2–15% of all central nervous system (CNS) tumors [ 1 ]. Most intraspinal tumors are benign, and about 40% of them are intradural [ 2 ], and early surgery is the treatment of choice [ 3 ]. Surgical methods …

  16. Open Access 07-10-2023 | Intramedullary Space-Occupying Lesion | OriginalPaper

    Predictors for spinal deformity following resection of intramedullary tumor via posterior approach: a systematic review and meta-analysis

    Intramedullary spinal cord tumors (IMSCTs) are rare forms of central nervous system (CNS) neoplasms with a prevalence as low as 2–10% of all CNS neoplasms and an incidence of less than 1/100,000 people per year [ 1 – 4 ]. It most commonly presents …

  17. Open Access 01-12-2023 | Glioma | OriginalPaper

    Tumor microenvironment in a minipig model of spinal cord glioma

    Spinal Cord Gliomas (SCGs) account for 4–8% of central nervous system (CNS) tumors, where high-grade lesions have a poor prognosis [ 1 ]. Most commonly, gross total resection is not an option in such lesions due to a lack of resectable margins and …

  18. 12-09-2023 | Spinal Metastasis | OriginalPaper

    The prognostic nutritional index (PNI) is independently associated with 90-day and 12-month mortality after metastatic spinal tumor surgery

    Malnutrition is common in cancer patients, with an estimated prevalence of 40% [ 1 ]. It is associated with prolonged hospitalizations and increased morbidity and mortality after oncologic surgery [ 2 ]. The prevalence of malnutrition in patients …

  19. 02-08-2023 | Motor Evoked Potential | OriginalPaper

    The efficacy of preoperative diffusion tensor tractography on surgical planning and outcomes in patients with intramedullary spinal tumor

    Diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) are currently among the leading techniques in advanced magnetic resonance imaging (MRI) of central nervous system (CNS) tumors. This is mainly due to their ability in …

  20. 09-05-2023 | Radiotherapy | ReviewPaper

    Spinal atypical teratoid rhabdoid tumor-narrative review and report of a rare case managed with multimodality approach

    Atypical teratoid/rhabdoid tumor (AT/RT) is a rare embryonal central nervous system (CNS) tumor commonly affecting children < 3 years of age [ 1 ]. It represents approximately 1–2% of all pediatric CNS tumors [ 1 ]. Recent data implies that it is …

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