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3456 search results for:

Raloxifene 

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  1. Open Access 06-09-2023 | Raloxifene | OriginalPaper

    Advantage of ostarine over raloxifene and their combined treatments for muscle of estrogen-deficient rats

    The aging of the world's population poses serious medical, social, and economic challenges. In postmenopausal women, hormonal changes such as estrogen decline contribute to the development of sarcopenia and osteoporosis [ 1 , 2 ]. Sarcopenia …

  2. 09-11-2023 | Denosumab | Erratum

    Correction to: The comparison of alendronate and raloxifene after denosumab (CARD) study: A comparative efficacy trial

  3. 06-10-2023 | Denosumab | OriginalPaper

    The comparison of alendronate and raloxifene after denosumab (CARD) study: A comparative efficacy trial

    Denosumab, a fully human monoclonal antibody that binds to and inhibits the receptor activator of nuclear factor kappa-B ligand (RANKL), is a widely used osteoporosis medication that increases bone mineral density (BMD), improves bone …

  4. 01-06-2023 | Breast Cancer | News

    Raloxifene

    Lack of efficacy: case report
  5. 01-08-2022 | Osteoporosis | News

    Raloxifene

    Corneal verticillate: case report
  6. 01-01-2023 | Breast Cancer | OriginalPaper

    Raloxifene potentiates the effect of gefitinib in triple-negative breast cancer cell lines

    Triple-negative breast cancers (TNBCs) are characterized by a lack of approved targeted therapies and remain a challenge in the clinic. Several overexpressed proteins, including epidermal growth factor receptor (EGFR), have been associated with …

  7. 13-11-2022 | Raloxifene | OriginalPaper

    Combined Thermoneutral Housing and Raloxifene Treatment Improves Trabecular Bone Microarchitecture and Strength in Growing Female Mice

    Thermoneutral housing and Raloxifene (RAL) treatment both have potential for improving mechanical and architectural properties of bone. Housing mice within a 30 to 32 °C range improves bone quality by reducing the consequences of cold stress, such …

  8. Open Access 28-01-2023 | Bisphosphonate | OriginalPaper

    Effect of Bone Resorption Inhibitors on Serum Cholesterol Level and Fracture Risk in Osteoporosis: Randomized Comparative Study Between Minodronic Acid and Raloxifene

    The positive link between osteoporosis and hypercholesterolemia has been documented, and bone resorption inhibitors, such as nitrogen-containing bisphosphonates (N-BP) and selective estrogen receptor modulators (SERMs), are known to reduce serum …

  9. 01-11-2021 | Erythema Exsudativum Multiforme | News

    Raloxifene

    Erythema multiforme minor: case report
  10. 04-04-2022 | Bisphosphonate | OriginalPaper

    Effect of follow-up raloxifene therapy after denosumab discontinuation in postmenopausal women

    Denosumab is an osteoporosis treatment with a potent antiresorptive effect [ 1 ]. It has been widely prescribed in Korea for the treatment of various osteoporotic diseases, including postmenopausal osteoporosis, male osteoporosis …

  11. 28-02-2022 | Bisphosphonate | OriginalPaper

    Raloxifene Use After Denosumab Discontinuation Partially Attenuates Bone Loss in the Lumbar Spine in Postmenopausal Osteoporosis

    Discontinuation of denosumab (DMab) is associated with decline in bone density. Whether raloxifene can be effective to attenuate bone loss after DMab discontinuation in certain conditions when other antiresorptives cannot be used remains unclear.

  12. 01-12-2021 | Osteoporosis

    A pilot study comparing daily teriparatide with monthly cycles of teriparatide and raloxifene

    Current osteoporosis medications increase BMD and reduce fracture risk. However, as bone mass and structure are not normalized and not all fractures prevented, improved medications or treatment strategies using currently available therapies are …

  13. 01-02-2021 | Osteonecrosis | News

    Raloxifene

    Medication-related osteonecrosis of the jaw: case report
  14. Open Access 01-12-2021 | Raloxifene | OriginalPaper

    Immersion in Raloxifene does not significantly improve bone toughness or screw pull-out strength in multiple in vitro models

    Osteoporotic fractures accounted for an estimated 9 million new fractures worldwide in the year 2000 and more than 2 million fractures in the United States in 2005 [ 1 , 2 ]. Globally, it is estimated frailty has a 10.7% prevalence in populations …

  15. Open Access 01-12-2021 | Ovariectomy | OriginalPaper

    Raloxifene retards the progression of adjacent segmental intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus in ovariectomized rats

    Lumbar spinal fusion is an effective surgery to treat spinal diseases as it can remove certain lumbar motions [ 1 ]. However, it is associated with caudad and cephalad motions near the fusion site, resulting in a high incidence of adjacent …

  16. 01-05-2021 | Tooth Extraction | OriginalPaper

    Morphological and immunohistochemical features of tooth extraction sites in rats treated with alendronate, raloxifene, or strontium ranelate

    Medication-related osteonecrosis of the jaw (MRONJ) is an important side effect of antiresorptive drugs, whose poor response to treatment can lead to lesion persistence for months or years [ 1 ]. When this condition is associated with oral …

  17. Open Access 01-02-2021 | Raloxifene | OriginalPaper

    Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ERβ and IL-6/gp130/STAT3 signaling

    Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with a dismal prognosis and a mortality rate closely paralleling its incidence [ 1 ]. The total number of deaths from pancreatic cancer is currently increasing and has been …

  18. 01-09-2020 | Schizophrenia | OriginalPaper

    Effects of raloxifene on cognition in postmenopausal women with schizophrenia: a 24-week double-blind, randomized, parallel, placebo-controlled trial

    We assessed the utility of raloxifene (60 mg/day) as an adjuvant treatment for cognitive symptoms in postmenopausal women with schizophrenia in a 24-week, double-blind, randomized, placebo-controlled study. Patients were recruited from the …

  19. 01-03-2020 | Osteoporosis | OriginalPaper

    Sequential Treatment of Estrogen Deficient, Osteopenic Rats with Alendronate, Parathyroid Hormone (1–34), or Raloxifene Alters Cortical Bone Mineral and Matrix Composition

    Anti-resorptive and anabolic treatments can be used sequentially to treat osteoporosis, but their effects on bone composition are incompletely understood. Osteocytes may influence bone tissue composition with sequential therapies because …

  20. 01-04-2024 | Raloxifene | News

    Alendronic-acid/raloxifene

    Lack of efficacy

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